Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-03-18Clinical Trial Update: Celecoxib in Patients With Newly Diagnosed GBM Who Are Receiving Anticonvulsant Drugs and Undergoing RT [Phase 2]
A Phase 2 trial of celecoxib in newly diagnosed glioblastoma patients receiving anticonvulsants and radiotherapy was terminated, with result…
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Safety Study of Replication-competent Adenovirus (Delta-24-rgd) in Patients With Recurrent Glioblastoma [Phase 1, Phase 2]
This is a completed Phase 1/2 safety study of replication-competent adenovirus Delta-24-RGD (DNX-2401) in patients with recurrent glioblasto…
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CLINICAL_TRIALS trial_result · 2015-01-07Clinical Trial Update: A Phase I Trial of Nanoliposomal CPT-11 (NL CPT-11) in Patients With Recurrent High-Grade Gliomas [Phase 1]
This report covers a Phase I trial of nanoliposomal irinotecan (NL-CPT-11) in patients with recurrent high-grade gliomas, completed to evalu…
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CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: Dasatinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma [Phase 2]
Phase 2 trial update evaluating dasatinib in patients with recurrent glioblastoma multiforme or gliosarcoma has completed.
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CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: CAR T Cells in Treating Patients With Malignant Gliomas Overexpressing EGFR [Phase 1]
A Phase 1 clinical trial is evaluating CAR T cells targeting EGFR in patients with malignant gliomas, including advanced glioma.
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors [Phase 1]
This Phase 1 trial evaluated the combination of RO4929097, a gamma-secretase inhibitor, with Cediranib maleate in adults with advanced solid…
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma [Phase 1]
Phase 1 trial evaluating high-dose vorinostat with fractionated SBRT in patients with recurrent glioma; the study has been terminated.
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CLINICAL_TRIALS trial_result · 2014-12-08Clinical Trial Update: Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Unmethylated Gene Promoter Status [Phase 2]
A Phase 2 clinical trial evaluated cilengitide in combination with temozolomide and radiation therapy for newly diagnosed glioblastoma with …
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CLINICAL_TRIALS trial_result · 2014-12-08Clinical Trial Update: A Study of Bevacizumab and Extended Treatment of Temozolomide in Patients With Recurrent Glioblastoma Multiforme [Phase 2]
Phase 2 trial update assessing bevacizumab with extended temozolomide in patients with recurrent glioblastoma; the study has completed and r…
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CLINICAL_TRIALS trial_result · 2014-11-14Clinical Trial Update: Study of Bevacizumab Plus Temodar and Tarceva in Patients With Glioblastoma or Gliosarcoma [Phase 2]
Phase 2 trial evaluating bevacizumab plus temozolomide (Temodar) and erlotinib (Tarceva) in glioblastoma and gliosarcoma; the study is compl…
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CLINICAL_TRIALS trial_result · 2014-11-14Clinical Trial Update: Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma [Phase 1, Phase 2]
The clinical trial evaluating interstitial infusion of IL13-PE38QQR cytotoxin in recurrent malignant glioma has completed Phase 1 and Phase …
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CLINICAL_TRIALS trial_result · 2014-11-04Clinical Trial Update: Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Methylated Gene Promoter Status [Phase 3]
Phase 3 trial evaluating cilengitide in combination with temozolomide and radiotherapy for newly diagnosed glioblastoma with MGMT promoter m…
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CLINICAL_TRIALS trial_result · 2014-11-04Clinical Trial Update: Sorafenib in Newly Diagnosed High Grade Glioma [Phase 1]
Phase 1 trial update evaluating sorafenib in newly diagnosed high-grade glioma, including glioblastoma, gliosarcoma, and various anaplastic …
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CLINICAL_TRIALS trial_result · 2014-10-30Clinical Trial Update: Immunotherapy for Patients With Brain Stem Glioma and Glioblastoma [Phase 1]
Phase 1 clinical trial investigating an immunotherapy approach for brainstem glioma and glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2014-10-13Clinical Trial Update: The Safety and Efficacy of DCA for the Treatment of Brain Cancer [Phase 2]
This Phase 2 trial update reports safety and efficacy data for dichloroacetate (DCA) in treating malignant gliomas, including glioblastoma m…
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CLINICAL_TRIALS trial_result · 2014-09-22Clinical Trial Update: Safety Study of XL184 (Cabozantinib) in Combination With Temozolomide and Radiation Therapy in the Initial Treatment of Adults With Glioblastoma [Phase 1]
A Phase 1 safety study evaluating cabozantinib (XL184) in combination with temozolomide and radiation for newly diagnosed glioblastoma has c…
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CLINICAL_TRIALS trial_result · 2014-09-15Clinical Trial Update: Imaging Study of Glioblastomas Treated With Avastin [NA]
This terminated imaging study evaluated glioblastoma patients treated with Avastin (bevacizumab); results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-08-22Clinical Trial Update: Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma [Phase 3]
A Phase 3 study of AP-12009 in recurrent or refractory anaplastic astrocytoma or secondary glioblastoma was terminated, and results have bee…
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CLINICAL_TRIALS trial_result · 2014-08-18Clinical Trial Update: BIBF 1120 for Recurrent High-Grade Gliomas [Phase 2]
Phase 2 trial update on BIBF 1120 (nintedanib) for recurrent high-grade gliomas, with the study status now completed and results posted in 2…
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CLINICAL_TRIALS trial_result · 2014-08-18Clinical Trial Update: Ph. II Treatment of Adults w Primary Malignant Glioma w Irinotecan + Temozolomide [Phase 2]
Phase II study of irinotecan plus temozolomide in adults with primary malignant glioma, including glioblastoma, has completed.
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CLINICAL_TRIALS trial_result · 2014-08-15Clinical Trial Update: Comparison of Two Dosing Regimens of Temozolomide in Patients With Progressive or Recurrent Glioblastoma [Phase 2]
Phase 2 trial comparing two dosing regimens of temozolomide in patients with progressive or recurrent glioblastoma.
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CLINICAL_TRIALS trial_result · 2014-07-21Clinical Trial Update: Ph I SU011248 + Irinotecan in Treatment of Pts w MG [Phase 1]
A Phase I trial evaluating SU011248 in combination with irinotecan for glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2014-07-16Clinical Trial Update: Ph I 5-day Temozolomide + O6-BG in Treatment of Pts w Recurrent / Progressive GBM [Phase 1]
A Phase I trial evaluating a 5-day regimen of temozolomide plus O6-benzylguanine in patients with recurrent or progressive glioblastoma and …
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CLINICAL_TRIALS trial_result · 2014-07-16Clinical Trial Update: Ph I Dasatinib + Erlotinib in Recurrent MG [Phase 1]
Duke University conducted a Phase 1 trial evaluating the combination of dasatinib and erlotinib in recurrent malignant glioma, including gli…
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CLINICAL_TRIALS trial_result · 2014-07-02Clinical Trial Update: Early Detection of Glioblastoma Multiforme (GBM) Treatment Responses Using Multiple Magnetic Resonance Modalities
This terminated clinical trial evaluated using multiple magnetic resonance imaging modalities to detect early treatment responses in gliobla…