Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-12-20Clinical Trial Update: Multimodal Imaging Analysis During Treatment With Bevacizumab in Patients With Recurrent Glioblastoma [NA]
This clinical trial update notes the termination of a study evaluating multimodal imaging analysis during Bevacizumab treatment in patients …
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme [Phase 2]
Phase 2 clinical trial evaluating the effectiveness and safety of combining chemotherapy with radiation therapy in patients with newly diagn…
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: CAR-T Cell Immunotherapy in MUC1 Positive Solid Tumor [Phase 1, Phase 2]
A Phase 1/2 CAR-T cell therapy targeting MUC1 is being investigated for glioblastoma, colorectal cancer, and gastric cancer.
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: FR901228 in Treating Patients With Recurrent High-Grade Gliomas [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluated FR901228 in adults with recurrent high-grade gliomas; results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of GDC-0084 in Patients With Progressive or Recurrent High-Grade Glioma [Phase 1]
Phase 1 study of GDC-0084 in patients with progressive or recurrent high-grade glioma has completed. Indications studied include glioblastom…
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CLINICAL_TRIALS trial_result · 2016-11-01Clinical Trial Update: Avastin Plus Radiotherapy in Elderly Patients With Glioblastoma [Phase 2]
A Phase 2 trial evaluated bevacizumab (Avastin) in combination with radiotherapy for elderly patients with glioblastoma; the study has compl…
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CLINICAL_TRIALS trial_result · 2016-10-12Clinical Trial Update: Temozolomide and Radiation Therapy With or Without Bevacizumab in Treating Patients With Newly Diagnosed Glioblastoma [Phase 3]
Phase 3 trial evaluating temozolomide with radiation therapy with or without bevacizumab in newly diagnosed glioblastoma; study completed wi…
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CLINICAL_TRIALS trial_result · 2016-10-04Clinical Trial Update: Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating an NY-ESO-1 vaccine therapy with or without sirolimus in patients whose tumors express NY-ESO-1.
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CLINICAL_TRIALS trial_result · 2016-09-28Clinical Trial Update: Phase II Trial of Neo-adjuvant Temozolomide Prior to Combined Temozolomide and Concurrent Accelerated Hypofractionated External Beam Radiotherapy Followed by Adjuvant Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme [NA]
A Phase II trial evaluating neoadjuvant temozolomide before concurrent temozolomide with accelerated hypofractionated external beam radiothe…
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CLINICAL_TRIALS trial_result · 2016-09-23Clinical Trial Update: Phase I/II Adaptive Randomized Trial of Bevacizumab Versus Bevacizumab Plus Vorinostat in Adults With Recurrent Glioblastoma [Phase 1, Phase 2]
Completed Phase I/II adaptive randomized trial comparing bevacizumab alone versus bevacizumab plus vorinostat in adults with recurrent gliob…
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CLINICAL_TRIALS trial_result · 2016-09-22Clinical Trial Update: Comparison of TransMID vs Standard Treatment of Cancerous Brain Tumors [Phase 3]
A Phase 3 clinical trial comparing TransMID against standard treatment for Glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2016-09-19Clinical Trial Update: Temozolomide and Radiation Therapy With or Without Cediranib Maleate in Treating Patients With Newly Diagnosed Glioblastoma [Phase 2]
A phase 2 clinical trial evaluated temozolomide plus radiation with or without cediranib maleate in newly diagnosed glioblastoma and gliosar…
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CLINICAL_TRIALS trial_result · 2016-09-13Clinical Trial Update: Temozolomide Plus Bevacizumab in Supratentorial Glioblastoma in 70 Years and Older Patients With an Impaired Functional Status [Phase 2]
A Phase 2 trial evaluating temozolomide in combination with bevacizumab in elderly patients (70 years and older) with supratentorial gliobla…
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CLINICAL_TRIALS trial_result · 2016-08-04Clinical Trial Update: Ph 1/2 CTO With Lomustine for Bevacizumab-Naive Recurrent Glioma [Phase 1]
A Phase 1 study evaluating lomustine for bevacizumab-naive recurrent malignant glioma has been terminated.
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CLINICAL_TRIALS trial_result · 2016-07-26Clinical Trial Update: Pilot Study of Autologous Anti-EGFRvIII CAR T Cells in Recurrent Glioblastoma Multiforme [Phase 1]
Phase 1 pilot study evaluating autologous anti-EGFRvIII CAR T cells in recurrent glioblastoma; the document notes the trial status but provi…
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CLINICAL_TRIALS trial_result · 2016-07-07Clinical Trial Update: Sunitinib Tumor Levels in Patients Not on Enzyme-Inducing Anti-Epileptic Drugs Undergoing Debulking Surgery for Recurrent Glioblastoma [EARLY_Phase 1]
An early Phase 1 study evaluated sunitinib concentrations in recurrent glioblastoma patients not taking enzyme-inducing antiepileptic drugs …
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CLINICAL_TRIALS trial_result · 2016-06-20Clinical Trial Update: Bosutinib in Adult Patients With Recurrent Glioblastoma [Phase 2]
Phase 2 trial results for bosutinib in adults with recurrent glioblastoma have been posted.
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CLINICAL_TRIALS trial_result · 2016-05-30Clinical Trial Update: Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery [Phase 1]
This clinical trial update reports on a Phase 1 study of the oncolytic herpes simplex virus HSV-1716 in children with refractory or recurren…
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CLINICAL_TRIALS trial_result · 2016-05-27Clinical Trial Update: Cellular Immunotherapy Study for Brain Cancer [Phase 1]
Phase 1 clinical trial update describes completion of a cellular immunotherapy study for brain tumors to assess safety and initial signals o…
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CLINICAL_TRIALS trial_result · 2016-05-23Clinical Trial Update: Clinical Study on 5-aminolevulinic Acid Hydrochloride (5-ALA) for Fluorescence-guided Resection of Malignant Gliomas [Phase 1, Phase 2]
Clinical trial update on 5-ALA hydrochloride for fluorescence-guided resection of malignant gliomas (Phase 1/Phase 2), now completed.
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CLINICAL_TRIALS trial_result · 2016-05-19Clinical Trial Update: Safety and Efficacy of Talampanel in Glioblastoma Multiforme [Phase 2]
Phase 2 trial results evaluate the safety and efficacy of Talampanel in Glioblastoma. The update reports outcomes from the Phase 2 study con…
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CLINICAL_TRIALS trial_result · 2016-05-19Clinical Trial Update: Dendritic Cell Cancer Vaccine for High-grade Glioma [Phase 2]
Phase 2 trial of a dendritic cell cancer vaccine for glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2016-05-16Clinical Trial Update: MRI Study With Ferumoxytol in Assessing Early Response in Patients With Glioblastoma Multiforme Receiving Temozolomide and Radiation Therapy [NA]
A completed trial evaluated MRI using ferumoxytol to assess early response in patients with glioblastoma receiving temozolomide and radiatio…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Dendritic Cell-Based Tumor Vaccine Adjuvant Immunotherapy of Human Glioblastoma Multiforme (WHO Grade IV Gliomas) [Phase 2]
A Phase 2 clinical trial investigating a dendritic cell–based tumor vaccine as adjuvant immunotherapy for glioblastoma.
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CLINICAL_TRIALS trial_result · 2016-05-05Clinical Trial Update: Clinical Study on the Safety and Tolerability of Macitentan in Combination With Dose-dense Temozolomide in Patients With Recurrent Glioblastoma [Phase 1]
Phase 1 study evaluating the safety and tolerability of macitentan in combination with dose-dense temozolomide in recurrent glioblastoma has…