Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: Bendamustine Hydrochloride in Treating Patients With Recurrent or Progressive Anaplastic Glioma [Phase 2]
Phase 2 trial of bendamustine hydrochloride in adults with recurrent or progressive anaplastic glioma has completed and results have been po…
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CLINICAL_TRIALS trial_result · 2017-05-16Clinical Trial Update: A Study to Evaluate Bevacizumab Alone or in Combination With Irinotecan for Treatment of Glioblastoma Multiforme (BRAIN) [Phase 2]
Phase 2 trial evaluating bevacizumab alone or in combination with irinotecan for glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Efficacy and Safety of Temodal vs Semustine in Subjects With Recurrent Glioblastoma or Anaplastic Astrocytoma (Study P03644) [Phase 3]
Phase 3 trial results update comparing Temodal (temozolomide) with semustine in recurrent glioblastoma and anaplastic astrocytoma has been c…
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Recurrent or Progressive Glioblastoma [Phase 2]
Phase 2 trial of RO4929097, a gamma-secretase/Notch pathway inhibitor, in recurrent or progressive glioblastoma was terminated. Results were…
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: 3T MRI Biomarkers of Glioma Treatment Response [EARLY_Phase 1]
An early-phase 1 trial evaluating 3T MRI biomarkers for glioma treatment response, sponsored by Vanderbilt-Ingram Cancer Center, has been te…
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Neoadjuvant Nivolumab in Glioblastoma [Phase 2]
A Phase 2 trial of neoadjuvant nivolumab for glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2017-04-10Clinical Trial Update: Effect of NovoTTF-100A Together With Temozolomide in Newly Diagnosed Glioblastoma Multiforme (GBM) [Phase 3]
Phase 3 trial evaluating NovoTTF-100A tumor treating fields in combination with temozolomide for newly diagnosed glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: Tandutinib in Treating Patients With Recurrent or Progressive Glioblastoma [Phase 1, Phase 2]
Clinical trial update for tandutinib in recurrent or progressive glioblastoma (Phase 1/2) reports completion with results posted in 2017. Th…
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma [EARLY_Phase 1]
An early Phase 1 trial of topotecan delivered via convection-enhanced delivery for high-grade glioma (WHO Grade III or IV) has completed.
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CLINICAL_TRIALS trial_result · 2017-03-28Clinical Trial Update: O(6)-Benzylguanine and Temozolomide in Treating Patients With Glioblastoma Multiforme That Did Not Respond to Previous Temozolomide and Radiation Therapy [Phase 2]
A Phase 2 trial of O6-benzylguanine in combination with temozolomide for glioblastoma that did not respond to prior temozolomide and radiati…
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CLINICAL_TRIALS trial_result · 2017-03-27Clinical Trial Update: Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases [NA]
A clinical trial comparing gadobutrol to gadopentetate dimeglumine or gadobenate dimeglumine before DCE-MRI in patients with multiple sclero…
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CLINICAL_TRIALS trial_result · 2017-03-21Clinical Trial Update: Treatment of High-grade Gliomas Using Hypofractionated Radiation Therapy -a Phase I Clinical Trial [NA]
A completed Phase I trial evaluating hypofractionated radiation therapy for high-grade gliomas to determine safety and the maximum tolerated…
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CLINICAL_TRIALS trial_result · 2017-03-20Clinical Trial Update: 18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas [NA]
Terminated trial evaluating 18F-FDOPA PET/CT or PET/MRI for measuring tumors in patients with newly diagnosed or recurrent gliomas; results …
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CLINICAL_TRIALS trial_result · 2017-03-15Clinical Trial Update: Pazopanib in Treating Patients With Recurrent Glioblastoma [Phase 2]
Phase 2 trial update of pazopanib for recurrent glioblastoma; results have been posted following study completion.
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors [Phase 1]
Phase 1 study of dendritic cell vaccine therapy with in situ maturation for pediatric brain tumors was terminated.
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CLINICAL_TRIALS trial_result · 2017-03-01Clinical Trial Update: Search for a Link Between Response to Treatment and Circulating Leucocytes in High Grade Glioma Patients [NA]
A completed clinical trial evaluating whether treatment response correlates with circulating leukocytes in high-grade glioma patients (gliob…
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: Vaccine Therapy and Sargramostim in Treating Patients With Malignant Glioma [Phase 1]
Phase 1 clinical trial evaluating a vaccine therapy in combination with sargramostim (GM-CSF) for malignant glioma, including several glioma…
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: Bevacizumab With or Without Trebananib in Treating Patients With Recurrent Brain Tumors [Phase 2]
Phase 2 trial evaluating bevacizumab with or without trebananib for recurrent brain tumors has completed enrollment with results posted.
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: Open-label Trial of Imatinib Mesylate in Patients With Unresectable Recurrent Glioblastoma Multiforme Expressing PDGFR (Platelet Derived Growth Factor Receptors) [Phase 2]
Open-label Phase 2 trial of imatinib mesylate in unresectable recurrent glioblastoma expressing PDGFR was terminated; the study status is TE…
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CLINICAL_TRIALS trial_result · 2017-02-15Clinical Trial Update: Aminolevulinic Acid During Surgery in Treating Patients With Malignant Brain Tumors [Phase 1]
Phase 1 clinical trial evaluating aminolevulinic acid during surgery for malignant brain tumors; the study was terminated.
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CLINICAL_TRIALS trial_result · 2017-02-08Clinical Trial Update: Image Guided Reirradiation of High-grade Glioma [Phase 1, Phase 2]
A phase 1/2 clinical trial of image-guided reirradiation for high-grade glioma has been terminated.
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Super-Selective Intraarterial Cerebral Infusion of Cetuximab (Erbitux) for Treatment of Relapsed/Refractory GBM and AA [Phase 1]
A Phase 1 clinical trial evaluating super-selective intraarterial infusion of cetuximab (Erbitux) for relapsed/refractory glioblastoma and a…
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CLINICAL_TRIALS trial_result · 2017-01-27Clinical Trial Update: Cediranib Maleate With or Without Gefitinib in Treating Patients With Recurrent or Progressive Glioblastoma [Phase 2]
A Phase 2 trial evaluating cediranib alone or with gefitinib in recurrent or progressive glioblastoma was terminated; results were posted in…
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CLINICAL_TRIALS trial_result · 2017-01-13Clinical Trial Update: Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas [Phase 2]
Phase 2 clinical trial evaluating radiation therapy with temozolomide and lomustine in young patients with newly diagnosed gliomas; complete…
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CLINICAL_TRIALS trial_result · 2017-01-05Clinical Trial Update: Dose Escalated MRSI Guided Radiation Therapy in Glioblastoma [Phase 2]
A Phase 2 trial evaluating dose-escalated MR spectroscopy imaging-guided radiation therapy for glioblastoma has been terminated, with result…