Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-07-01Clinical Trial Update: Nivolumab, Ipilimumab, and Short-course Radiotherapy in Adults With Newly Diagnosed, MGMT Unmethylated Glioblastoma [Phase 2]
Phase 2 trial assessing nivolumab, ipilimumab, and short-course radiotherapy in adults with MGMT-unmethylated glioblastoma; study completed …
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CLINICAL_TRIALS trial_result · 2022-06-29Clinical Trial Update: A Study of the Effectiveness and Safety of Nivolumab Compared to Bevacizumab and of Nivolumab With or Without Ipilimumab in Glioblastoma Patients [Phase 3]
Phase 3 trial comparing nivolumab to bevacizumab and evaluating nivolumab with or without ipilimumab in recurrent glioblastoma, with results…
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CLINICAL_TRIALS trial_result · 2022-06-29Clinical Trial Update: Avelumab With Hypofractionated Radiation Therapy in Adults With Isocitrate Dehydrogenase (IDH) Mutant Glioblastoma [Phase 2]
Phase 2 trial evaluating avelumab with hypofractionated radiation therapy in IDH-mutant glioblastoma completed with posted results.
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CLINICAL_TRIALS trial_result · 2022-06-23Clinical Trial Update: TTFields and Pulsed Bevacizumab for Recurrent Glioblastoma [Phase 2]
Phase 2 trial update on TTFields combined with pulsed bevacizumab for recurrent glioblastoma has been terminated.
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CLINICAL_TRIALS trial_result · 2022-06-08Clinical Trial Update: Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and Bevacizumab [Phase 1, Phase 2]
Phase 1/2 trial evaluating marizomib with bevacizumab, then marizomib alone, then marizomib with bevacizumab in malignant glioma/glioblastom…
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CLINICAL_TRIALS trial_result · 2022-05-31Clinical Trial Update: A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma [Phase 1, Phase 2]
Phase 1/2 study evaluating pamiparib with radiation and/or temozolomide for newly diagnosed or recurrent glioblastoma; status completed with…
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CLINICAL_TRIALS trial_result · 2022-05-18Clinical Trial Update: Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer [Phase 3]
A Phase 3 clinical trial update for DCVax-L in newly diagnosed glioblastoma multiforme is reported with unknown current status.
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CLINICAL_TRIALS trial_result · 2022-04-18Clinical Trial Update: Tremelimumab and Durvalumab in Combination or Alone in Treating Patients With Recurrent Malignant Glioma [Phase 2]
Phase 2 trial evaluating tremelimumab and durvalumab, alone or in combination, for recurrent malignant glioma including recurrent glioblasto…
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CLINICAL_TRIALS trial_result · 2022-04-12Clinical Trial Update: A Study of DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade Gliomas [Phase 1, Phase 2]
Phase 1/2 trial of DSP-7888 in pediatric patients with relapsed or refractory high-grade gliomas has completed.
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CLINICAL_TRIALS trial_result · 2022-03-29Clinical Trial Update: Innovative SonoCloud-9 Device for Blood Brain Barrier Opening in First Line Temozolomide Glioblastoma Patients. [Phase 2]
Phase 2 trial evaluating SonoCloud-9 device for transient opening of the blood-brain barrier in first-line temozolomide-treated glioblastoma…
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CLINICAL_TRIALS trial_result · 2022-02-24Clinical Trial Update: BrUOG 329 Onivyde & Metronomic Temozolomide in Recurrent Glioblastoma [Phase 1, Phase 2]
Phase 1/2 trial of Onivyde with metronomic temozolomide in recurrent glioblastoma has been terminated; results posted prior to termination.
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CLINICAL_TRIALS trial_result · 2022-02-03Clinical Trial Update: An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer) [Phase 3]
Phase 3 trial evaluating temozolomide plus radiation therapy with nivolumab or placebo for newly diagnosed glioblastoma has completed, with …
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CLINICAL_TRIALS trial_result · 2022-02-03Clinical Trial Update: Optune(NOVOTTF-100A)+ Bevacizumab+ Hypofractionated Stereotactic Irradiation Bevacizumab-Naive Recurrent Glioblastoma (GCC 1344) [NA]
Clinical trial update for Optune (NOVOTTF-100A) + Bevacizumab + Hypofractionated Stereotactic Irradiation in bevacizumab-naive recurrent gli…
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CLINICAL_TRIALS trial_result · 2022-02-01Clinical Trial Update: DC Migration Study for Newly-Diagnosed GBM [Phase 2]
Phase 2 clinical trial update on dendritic cell migration for newly diagnosed glioblastoma; study completed with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-02-01Clinical Trial Update: Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas [Phase 1, Phase 2]
Phase I/II trial evaluating everolimus and sorafenib in recurrent high-grade gliomas has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-12-16Clinical Trial Update: Autologous Dendritic Cells Loaded With Autologous Tumor Associated Antigens for Treatment of Newly Diagnosed Glioblastoma [Phase 2]
Phase 2 trial investigating autologous dendritic cells loaded with autologous tumor associated antigens for newly diagnosed glioblastoma.
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CLINICAL_TRIALS trial_result · 2021-11-30Clinical Trial Update: Neoadjuvant PD-1 Antibody Alone or Combined With DC Vaccines for Recurrent Glioblastoma [Phase 2]
Phase 2 trial evaluating neoadjuvant PD-1 antibody alone or with dendritic cell vaccines for recurrent glioblastoma is in progress with unkn…
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CLINICAL_TRIALS trial_result · 2021-11-23Clinical Trial Update: Combination of Stereotactic Radiosurgery and Enhanced Immunotherapy for Recurrent Glioblastomas(inSituVac2)(CSREIG) [Phase 1, Phase 2]
A clinical trial evaluating combination of stereotactic radiosurgery with enhanced immunotherapy for recurrent glioblastoma is in Phase 1/Ph…
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CLINICAL_TRIALS trial_result · 2021-11-09Clinical Trial Update: Peptide Targets for Glioblastoma Against Novel Cytomegalovirus Antigens [Phase 1]
Phase 1 trial evaluating peptide targets for glioblastoma against novel cytomegalovirus antigens; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2021-10-28Clinical Trial Update: Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Glioma [Phase 2]
A Phase 2 trial evaluating a combination of sorafenib, valproic acid, and sildenafil in patients with recurrent high-grade glioma has comple…
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CLINICAL_TRIALS trial_result · 2021-10-05Clinical Trial Update: A Proof-of-concept Clinical Trial Assessing the Safety of the Coordinated Undermining of Survival Paths by 9 Repurposed Drugs Combined With Metronomic Temozolomide (CUSP9v3 Treatment Protocol) for Recurrent Glioblastoma [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating CUSP9v3, a combination of 9 repurposed drugs with metronomic temozolomide, in recurrent glioblastoma; …
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CLINICAL_TRIALS trial_result · 2021-09-29Clinical Trial Update: Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas [Phase 1]
Phase 1 trial evaluating genetically modified neural stem cells with flucytosine and leucovorin for recurrent high-grade gliomas; results co…
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CLINICAL_TRIALS trial_result · 2021-09-28Clinical Trial Update: Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma [Phase 1, Phase 2]
This ClinicalTrials.gov update reports a terminated Phase 1/2 study evaluating Zotiraciclib (TG02) in combination with dose-dense or metrono…
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CLINICAL_TRIALS trial_result · 2021-09-24Clinical Trial Update: A Study of BBI608 in Combination With Temozolomide in Adult Patients With Recurrent or Progressed Glioblastoma [Phase 1, Phase 2]
Clinical trial update for BBI608 in combination with temozolomide in adults with recurrent or progressed glioblastoma (Phase 1/Phase 2) comp…
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CLINICAL_TRIALS trial_result · 2021-09-22Clinical Trial Update: Study of Tesevatinib Monotherapy in Patients With Recurrent Glioblastoma [Phase 2]
Phase 2 trial of tesevatinib monotherapy in recurrent glioblastoma has completed with posted results.