Glioblastoma
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CLINICAL_TRIALS trial_result · 2023-11-14Clinical Trial Update: 18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy [Phase 2]
Phase 2 trial evaluating 18F-DOPA-PET/MRI imaging in elderly patients with newly diagnosed grade IV malignant glioma or glioblastoma during …
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: Nab-sirolimus in Recurrent High Grade Glioma and Newly Diagnosed Glioblastoma [Phase 2]
Phase 2 trial updates Nab-sirolimus for recurrent high-grade glioma and newly diagnosed glioblastoma, completion status with results posted …
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CLINICAL_TRIALS trial_result · 2023-11-01Clinical Trial Update: Imaging Perfusion Restrictions From Extracellular Solid Stress - An Open-label Losartan Study [Phase 2]
Phase 2 open-label trial assessing losartan with imaging perfusion restrictions related to extracellular solid stress in glioblastoma and br…
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CLINICAL_TRIALS trial_result · 2023-10-04Clinical Trial Update: TORC1/2 Inhibitor MLN0128 and Bevacizumab in Treating Patients With Recurrent Glioblastoma or Advanced Solid Tumors [Phase 1]
Phase 1 results for a study combining the TORC1/2 inhibitor MLN0128 (sapanisertib) with bevacizumab in adults with recurrent glioblastoma or…
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: NCT Neuro Master Match - N²M² (NOA-20) [Phase 1, Phase 2]
Clinical trial update for NCT03158389 (N²M² NOA-20) across Phase 1/Phase 2 completed, investigating glioblastoma in adults.
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CLINICAL_TRIALS trial_result · 2023-09-22Clinical Trial Update: Pilot Study of Anlotinib With STUPP Regimen for Patients With Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
A pilot study investigating anlotinib combined with the STUPP regimen in newly diagnosed glioblastoma has completed Phase 1 and Phase 2 tria…
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CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: Anti-GITR/Anti-PD1/Stereotactic Radiosurgery, in Recurrent Glioblastoma [Phase 2]
Phase 2 trial update showing results for a combination of anti-GITR and anti-PD1 therapy with stereotactic radiosurgery in recurrent gliobla…
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CLINICAL_TRIALS trial_result · 2023-09-08Clinical Trial Update: Disulfiram and Copper Gluconate With Temozolomide in Unmethylated Glioblastoma Multiforme [Phase 2]
Phase 2 trial evaluating the combination of disulfiram, copper gluconate, and temozolomide for unmethylated glioblastoma multiforme was term…
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CLINICAL_TRIALS trial_result · 2023-08-31Clinical Trial Update: The Assessment of Immune Response in Newly Diagnosed Glioblastoma Patients Treated With Pembrolizumab [Phase 4]
Phase 4 clinical trial update assessing immune response in newly diagnosed glioblastoma patients treated with pembrolizumab.
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CLINICAL_TRIALS trial_result · 2023-07-24Clinical Trial Update: A Trial of One-week on/One-week Off Temozolomide Versus Continuous Dose-Intense Temozolomide in Patients With Glioblastoma Multiforme at First Relapse [Phase 2]
Phase 2 trial comparing one-week-on/one-week-off temozolomide versus continuous dose-dense temozolomide in patients with glioblastoma at fir…
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CLINICAL_TRIALS trial_result · 2023-07-17Clinical Trial Update: Stereotactic Radiology Versus Chemotherapy for Recurrent/Progressive Glioblastoma After Second-Line Chemotherapy [Phase 3]
A Phase 3 trial comparing stereotactic radiology versus chemotherapy for recurrent or progressive glioblastoma after second-line chemotherap…
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CLINICAL_TRIALS trial_result · 2023-06-29Clinical Trial Update: Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma [Phase 2]
Phase 2 trial updating safety and efficacy of TVI-Brain-1 for recurrent grade IV glioma; results posted after completion.
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CLINICAL_TRIALS trial_result · 2023-06-28Clinical Trial Update: TTFields and Radiosurgery of Recurrent Glioblastoma +/- 18F-Fluoro-Ethyl-Thyrosine [Phase 2]
Phase 2 clinical trial evaluating TTFields with radiosurgery for recurrent glioblastoma, with auxiliary imaging using 18F-Fluoro-Ethyl-Thyro…
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With Glioblastoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating autologous CMV-specific cytotoxic T cells with temozolomide in glioblastoma has completed with posted results.
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CLINICAL_TRIALS trial_result · 2023-06-12Clinical Trial Update: GX-I7 in Combination With Bevacizumab in Recurrent Glioblastoma (GBM) Patients [Phase 2]
Phase 2 trial update on GX-I7 in combination with bevacizumab for recurrent glioblastoma is reported as ongoing with unknown status.
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CLINICAL_TRIALS trial_result · 2023-06-06Clinical Trial Update: Cediranib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating cediranib with temozolomide and radiation therapy for newly diagnosed glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2023-06-06Clinical Trial Update: Improving Tumor Treating Fields Treatment for Brain Cancer Patients With Skullremodeling Surgery (Neurosurgery) [Phase 2]
Phase 2 trial update for skull remodeling surgery combined with Tumor Treating Fields in recurrent glioblastoma.
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CLINICAL_TRIALS trial_result · 2023-05-22Clinical Trial Update: Phase I/II Trial of AXL1717 in the Treatment of Recurrent Malignant Astrocytomas [Phase 1, Phase 2]
Phase I/II trial of AXL1717 in recurrent malignant astrocytomas (glioblastoma, gliosarcoma) with terminated status and results posted.
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CLINICAL_TRIALS trial_result · 2023-05-12Clinical Trial Update: GC1118 in Recurrent Glioblastoma Patients With High EGFR Amplification [Phase 2]
Phase 2 trial update for GC1118 in recurrent glioblastoma with high EGFR amplification has completed.
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CLINICAL_TRIALS trial_result · 2023-05-11Clinical Trial Update: A Study of ABT-414 in Participants With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification [Phase 3]
Phase 3 trial of ABT-414 in newly diagnosed glioblastoma with EGFR amplification completed; results were posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-05-06Clinical Trial Update: MRSI to Predict Response to RT/TMZ ± Belinostat in GBM [Phase 2]
Phase 2 trial investigating MR spectroscopy-guided response to radiotherapy and temozolomide with or without belinostat in glioblastoma mult…
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CLINICAL_TRIALS trial_result · 2023-04-26Clinical Trial Update: A Study of the Safety, Tolerability, and Efficacy of Epacadostat Administered in Combination With Nivolumab in Select Advanced Cancers (ECHO-204) [Phase 1, Phase 2]
Phase 1/2 study evaluating Epacadostat in combination with Nivolumab in select advanced cancers; results have been posted following completi…
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CLINICAL_TRIALS trial_result · 2023-04-10Clinical Trial Update: AV-GBM-1 vs Control as Adjunctive Therapy Following Surgery and RT/TMZ in Newly Diagnosed GBM [Phase 3]
Phase 3 trial update comparing AV-GBM-1 to control as adjunctive therapy after surgery and standard treatment for newly diagnosed primary gl…
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CLINICAL_TRIALS trial_result · 2023-04-07Clinical Trial Update: Pembrolizumab and Reirradiation in Bevacizumab Naïve and Bevacizumab Resistant Recurrent Glioblastoma [Phase 2]
Phase 2 trial evaluating pembrolizumab with reirradiation in bevacizumab-naïve and bevacizumab-resistant recurrent glioblastoma; results pos…
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CLINICAL_TRIALS trial_result · 2023-04-04Clinical Trial Update: Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme [Phase 2, Phase 3]
Clinical trial update reporting results from a Phase 2/3 study of temozolomide with or without veliparib in newly diagnosed glioblastoma, wi…