Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-04-15Clinical Trial Update: Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune®) Plus Pembrolizumab in Patients With Newly Diagnosed Glioblastoma (2-THE-TOP) [Phase 2]
Phase 2 trial evaluating the safety and efficacy of adjuvant temozolomide plus TTFields (Optune) and pembrolizumab in newly diagnosed gliobl…
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CLINICAL_TRIALS trial_result · 2024-04-15Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of TJ107 in Lympopenic Patients With Newly Diagnosed Glioblastoma Who Completed Standard Concurrent Chemoradiotherapy (CCRT) [Phase 2]
Phase 2 clinical trial evaluating TJ107 for efficacy and safety in lympopenic patients with newly diagnosed glioblastoma who completed stand…
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CLINICAL_TRIALS trial_result · 2024-04-10Clinical Trial Update: Effectiveness of MR-guided LITT Therapy in Irresectable Glioblastoma (EMITT) [Phase 3]
Phase 3 trial update evaluating MR-guided laser interstitial thermal therapy (LITT) for irresectable glioblastoma (EMITT).
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CLINICAL_TRIALS trial_result · 2024-04-08Clinical Trial Update: Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children [Phase 1]
Phase 1b trial update for PVSRIPO in recurrent malignant glioma in children has completed enrollment and results posted.
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CLINICAL_TRIALS trial_result · 2024-04-08Clinical Trial Update: Immunotherapy Targeted Against Cytomegalovirus in Patients With Newly-Diagnosed WHO Grade IV Unmethylated Glioma [Phase 2]
Phase 2 trial evaluating an immunotherapy targeting cytomegalovirus in newly diagnosed unmethylated glioma (glioblastoma) has been terminate…
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: Phase 3 Randomized, Double-blind, Controlled Study of ICT-107 in Glioblastoma [Phase 3]
Phase 3 randomized trial of ICT-107 in glioblastoma is suspended.
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: Dendritic Cell Immunotherapy Against Cancer Stem Cells in Glioblastoma Patients Receiving Standard Therapy [Phase 2, Phase 3]
A clinical trial update for a dendritic cell immunotherapy targeting cancer stem cells in glioblastoma patients undergoing standard therapy,…
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CLINICAL_TRIALS trial_result · 2024-03-28Clinical Trial Update: Glasdegib (PF-04449913) With Temozolomide Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
Clinical trial update involving glasdegib with temozolomide for newly diagnosed glioblastoma (Phase 1/Phase 2) completed.
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CLINICAL_TRIALS trial_result · 2024-03-27Clinical Trial Update: Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors [Phase 1, Phase 2]
Clinical trial updates the evaluation of an IDO inhibitor in combination with temozolomide for adult malignant brain tumors, including gliob…
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CLINICAL_TRIALS trial_result · 2024-03-06Clinical Trial Update: Study of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGG [Phase 2]
A Phase 2 study of the MEK inhibitor binimetinib plus the BRAF inhibitor encorafenib in adults with recurrent BRAF V600-mutant high-grade gl…
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CLINICAL_TRIALS trial_result · 2024-03-04Clinical Trial Update: Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM [Phase 1]
Phase 1 trial updating tumor treating fields in combination with chemoradiation for newly diagnosed glioblastoma (terminated; results posted…
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CLINICAL_TRIALS trial_result · 2024-02-29Clinical Trial Update: Bortezomib and Temozolomide in Recurrent Grade-4 Glioma Unmethylated MGMT Promoter (BORTEM-17) [Phase 1, Phase 2]
A clinical trial investigating bortezomib and temozolomide for recurrent Grade-4 glioma with unmethylated MGMT promoter (BORTEM-17) is in Ph…
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM) [Phase 2]
A Phase 2 trial evaluating Radiation Therapy plus Temozolomide and Pembrolizumab with and without HSPPC-96 in newly diagnosed glioblastoma w…
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Efficacy and Safety of TMZ Plus 6-MP in the Patients With Recurrent Glioblastoma [Phase 1, Phase 2]
Clinical trial investigating the safety and efficacy of temozolomide (TMZ) plus 6-mercaptopurine (6-MP) in patients with recurrent glioblast…
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CLINICAL_TRIALS trial_result · 2024-02-26Clinical Trial Update: SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma (SURVIVE) [Phase 2]
Phase 2 clinical trial update evaluating SurVaxM plus adjuvant temozolomide in newly diagnosed glioblastoma.
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: Cediranib Maleate and Olaparib Compared to Bevacizumab in Treating Patients With Recurrent Glioblastoma [Phase 2]
Phase 2 trial comparing Cediranib and Olaparib against Bevacizumab in patients with recurrent glioblastoma; results were posted in February …
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: Genetically Engineered HSV-1 Phase 1 Study for the Treatment of Recurrent Malignant Glioma [Phase 1]
This entry describes a Phase 1 clinical trial of a genetically engineered HSV-1 therapy for recurrent malignant glioma, including glioblasto…
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: A Phase III Trial of With Marizomib in Patients With Newly Diagnosed Glioblastoma [Phase 3]
A Phase III trial evaluating Marizomib in patients with newly diagnosed glioblastoma has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: Trial of Hypofractionated Radiation Therapy for Glioblastoma [Phase 2]
Phase 2 trial evaluating hypofractionated radiation therapy for glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: Biodistribution and Safety of the PET Probes [18F]FPRGD2 and [18F]FPPRGD2 [EARLY_Phase 1]
Phase 1 trial update assessing biodistribution and safety of PET probes [18F]FPRGD2 and [18F]FPPRGD2 in cancer patients; results posted afte…
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CLINICAL_TRIALS trial_result · 2024-01-03Clinical Trial Update: Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas [Phase 1]
Phase 1 trial evaluating adavosertib with local radiation in children with newly diagnosed diffuse intrinsic pontine glioma; results are pos…
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CLINICAL_TRIALS trial_result · 2024-01-02Clinical Trial Update: Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas [Phase 1]
A pediatric Phase 1 trial evaluating selinexor in children with recurrent or refractory solid tumors and high-grade gliomas has completed. R…
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CLINICAL_TRIALS trial_result · 2024-01-02Clinical Trial Update: Cisplatin Plus Temozolomide Compared With Temozolomide in Patients With MGMT Promotor Unmethylated Glioblastoma [Phase 1, Phase 2]
A clinical trial comparing cisplatin plus temozolomide to temozolomide alone in MGMT promoter unmethylated glioblastoma is in Phase 1/2 with…
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CLINICAL_TRIALS trial_result · 2023-12-06Clinical Trial Update: Safety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma Multiforme [Phase 1, Phase 2]
This update reports the results of a Phase 1/2 study evaluating SL-701, a glioma-associated antigen vaccine, in patients with recurrent glio…
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CLINICAL_TRIALS trial_result · 2023-11-30Clinical Trial Update: Standard Chemotherapy vs. Chemotherapy Guided by Cancer Stem Cell Test in Recurrent Glioblastoma [Phase 3]
A Phase 3 trial comparing standard chemotherapy versus chemotherapy guided by a cancer stem cell test in patients with recurrent glioblastom…