Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-07-26Clinical Trial Update: A Study of Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Subjects With Recurrent GBM [Phase 1, Phase 2]
This terminated Phase 1/2 trial evaluated sonodynamic therapy using SONALA-001 in combination with the Exablate 4000 Type 2.0 device for rec…
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade [Phase 1]
This Phase 1 trial investigates cytokine microdialysis for real-time immune monitoring in glioblastoma patients undergoing checkpoint blocka…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: Evaluating Therapeutic Response to Novo-TTF [NA]
This clinical trial update reports the completion of a trial evaluating therapeutic response to Novo-TTF therapy in glioblastoma.
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas [Phase 1, Phase 2]
A Phase I/Phase II study evaluating mebendazole for pediatric gliomas has completed. It enrolled children with various glial tumors, includi…
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma [Phase 1]
Phase 1 study of CC-90010 assesses CNS penetration, pharmacokinetics, and pharmacodynamics in progressive/recurrent diffuse astrocytoma, ana…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Tumor Treating Fields for Newly Diagnosed Glioblastoma: Two Emulated Trials With Chinese Multi-Hospital Based Real-World Data
Two emulated real-world trials using multi-hospital Chinese data evaluated Tumor Treating Fields for newly diagnosed glioblastoma; the study…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Multimodal MR Imaging in Patients With Glioblastoma Treated With Dendritic Cell Therapy
This clinical trial update reports on multimodal MRI imaging findings in glioblastoma patients treated with dendritic cell therapy.
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors [Phase 1]
A Phase 1 study of PRT3645 conducted by Prelude Therapeutics in patients with several advanced solid tumors has completed, including breast …
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma [Phase 2]
A Phase 2 clinical trial assessing the addition of plerixafor to standard temozolomide-based chemoradiotherapy for glioblastoma has complete…
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Phase 1/2a Study of Oral BAL101553 in Adult Patients With Solid Tumors or Glioblastoma or High-grade Glioma [Phase 1, Phase 2]
This ClinicalTrials.gov update reports that results for the Phase 1/2a trial of oral BAL101553 in adults with solid tumors, glioblastoma, an…
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluation [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating the pharmacodynamics and pharmacokinetics of evolocumab (a PCSK9 inhibitor) in patients with mali…
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CLINICAL_TRIALS trial_result · 2024-06-24Clinical Trial Update: Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma [Phase 1]
A Phase 1 trial evaluating BAL101553 in combination with radiation for newly diagnosed glioblastoma was terminated, with results posted in 2…
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CLINICAL_TRIALS trial_result · 2024-06-17Clinical Trial Update: 18F-FluorThanatrace (PET/CT) in Glioblastoma [EARLY_Phase 1]
An early-phase 1 trial evaluating 18F-FluorThanatrace PET/CT in glioblastoma has been terminated.
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CLINICAL_TRIALS trial_result · 2024-06-05Clinical Trial Update: Sintilimab in Combination With Bevacizumab and Temozolomide in Recurrent Glioblastoma (GBM) Patients [Phase 2]
Phase 2 clinical trial evaluating the combination of sintilimab, bevacizumab, and temozolomide for recurrent glioblastoma; status details ar…
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CLINICAL_TRIALS trial_result · 2024-05-31Clinical Trial Update: SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors [Phase 1]
The SJDAWN Phase 1 trial at St. Jude evaluated molecularly-driven doublet therapies for children and young adults with recurrent brain tumor…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Phase 2 Study to Investigate the Efficacy and Safety of Aldoxorubicin in Subjects With Glioblastoma [Phase 2]
Phase 2 study evaluating the efficacy and safety of Aldoxorubicin in glioblastoma has completed, with results posted in 2024-05-29.
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CLINICAL_TRIALS trial_result · 2024-05-23Clinical Trial Update: IRD at Admission Predicts Survival of GBM Patients - a Prospective Pilot Study
A completed prospective pilot study evaluating whether IRD at admission predicts survival in patients with glioblastoma.
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Evaluating the Effect of a Mobile Audio Companion (Elly) to Reduce Anxiety in Cancer Patients [NA]
This clinical trial update notes the completion of a study evaluating Elly, a mobile audio companion, intended to reduce anxiety in cancer p…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Bavituximab With Radiation and Temozolomide for Patients With Newly Diagnosed Glioblastoma [Phase 2]
Phase 2 trial evaluating bavituximab in combination with radiation and temozolomide for newly diagnosed glioblastoma has completed, with res…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Lapatinib With Temozolomide and Regional Radiation Therapy for Patients With Newly-Diagnosed Glioblastoma Multiforme [Phase 2]
This Phase 2 trial update reports on combining lapatinib with temozolomide and regional radiation therapy for patients with newly diagnosed …
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: Response Prediction for Anti-angiogenic Treatment in Recurrent Glioblastoma
Completed clinical trial evaluating biomarkers predicting response to anti-angiogenic therapy in recurrent glioblastoma.
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma [Phase 2, Phase 3]
This update reports the results of a randomized Phase 2/3 trial comparing ipilimumab and nivolumab with radiation therapy versus the standar…
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas [Phase 1]
Phase 1 clinical trial update evaluating safety and preliminary efficacy of carboxylesterase-expressing allogeneic neural stem cells in comb…
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations [Phase 2]
Phase 2 clinical trial evaluating veliparib in combination with radiation therapy and temozolomide for newly diagnosed malignant glioma; res…
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CLINICAL_TRIALS trial_result · 2024-04-22Clinical Trial Update: A Trial of Enzastaurin Plus Temozolomide During and Following Radiation Therapy in Patients With Newly Diagnosed Glioblastoma With or Without the Novel Genomic Biomarker, DGM1 [Phase 3]
Phase 3 trial evaluating enzastaurin plus temozolomide with/without a novel biomarker in newly diagnosed glioblastoma; study completed.