Glioblastoma
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Comprehensive Evaluation of Tumor Oxygenation, Metabolism and Blood Supply of High Grade Glioma and Cervical Cancers Using Dynamic FAZA PET and Multiparametric MR [EARLY_Phase 1]
This early-phase study is evaluating tumor oxygenation, metabolism, and blood supply in high-grade glioma and cervical cancer using Dynamic …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Couples-Based Yoga Program in Improving Quality of Life in Patients With High-Grade Glioma Undergoing Radiation Therapy and Their Partners [NA]
This clinical trial at MD Anderson Cancer Center is evaluating a couples-based yoga program to improve quality of life for patients with hig…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Lutathera (177Lu-DOTATATE) in combination with Olaparib for somatostatin receptor–expressing recurrent…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Phase 1/2 Study of the Safety and Tolerability of MT-125 in GBM Patients [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the safety and tolerability of MT-125 in patients with glioblastoma. The study is currently recruiting…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Personalized Targeted Glioblastoma Therapies by ex Vivo Drug Screening [NA]
A clinical trial update describes a study on personalized targeted therapies for glioblastoma using ex vivo drug screening, conducted by the…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the addition of selinexor to temozolomide for recurrent glioblastoma, including MGMT-methylated and…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastoma [Phase 1, Phase 2]
An update on a Phase 1/2 clinical trial evaluating ultrasound-induced opening of the blood-brain barrier in combination with albumin-bound p…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss [Phase 1, Phase 2]
The document provides an update on a Phase 1/2 clinical trial assessing the safety and tolerability of TNG456 alone and with abemaciclib in …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma [Phase 2]
A Phase 2 clinical trial update examining the combination of dabrafenib and trametinib after radiation therapy for newly diagnosed high-grad…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Evaluate the Safety and Preliminary Efficacy of the Combination of NaviFUS System With Re-irradiation for rGBM Patients [NA]
Clinical trial update on combining the NaviFUS System with re-irradiation for recurrent glioblastoma and high-grade glioma (WHO III–IV); the…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Efficacy of Mirdametinib Alone or Combination With Radiotherapy for Germline and Sporadic NF1-Altered High-Grade Glioma [Phase 2]
Phase 2 trial evaluating Mirdametinib alone or with radiotherapy for germline and sporadic NF1-altered high-grade glioma; status is not yet …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA [Phase 2]
Phase 2 clinical trial investigating super selective intra-arterial cetuximab with reirradiation for relapsed or refractory glioblastoma, an…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: CART-EGFR-IL13Ra2 in EGFR Amplified Recurrent GBM [Phase 1]
Trial update for a Phase 1 CART-T therapy called CART-EGFR-IL13Ra2 in EGFR-amplified recurrent glioblastoma; the study is currently active b…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: NBM-BMX Administered Orally to Patients With Solid Tumors or Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating oral NBM-BMX in patients with solid tumors or newly diagnosed glioblastoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients [Phase 3]
A Phase 3 prospective study evaluating bevacizumab with or without microbubble-mediated focused ultrasound (NaviFUS) in recurrent glioblasto…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Study Assessing if it is Safe and Possible to Treat Brain Cancer Patients With Immunotherapy Before They Receive the Standard Treatment. [Phase 1]
A Phase 1 trial is evaluating whether immunotherapy can be safely given to adults with glioblastoma or gliosarcoma before their standard tre…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM) [Phase 1, Phase 2]
A clinical trial update on safety and efficacy of combining bevacizumab with the NaviFUS system for recurrent glioblastoma multiforme, curre…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma [Phase 1]
This Clinical Trial Update describes a Phase 1 study of hypofractionated re-irradiation for good-prognosis recurrent glioblastoma, sponsored…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating laser interstitial thermotherapy (LITT) combined with a checkpoint inhibitor for recurrent glioblastoma;…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Glioblastoma Remote Monitoring and Care - Research Protocol [NA]
This document outlines a remote monitoring and care research protocol for patients with glioblastoma, including considerations for venous th…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Oral Gallium Maltolate for Recurrent Glioblastoma [EARLY_Phase 1]
This document reports an early-phase clinical trial evaluating oral gallium maltolate for recurrent Glioblastoma; the study is not yet recru…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma [Phase 1]
A Phase 1 pediatric trial of SurVaxM for progressive or relapsed medulloblastoma, high-grade glioma, ependymoma, and newly diagnosed diffuse…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Prophylactic Regimen With Intrathecal Thiotepa in SVZ-positive or Meningeal-risk Glioblastoma [Phase 2]
A Phase 2 clinical trial is evaluating prophylactic intrathecal thiotepa for SVZ-positive or meninges-risk glioblastoma, currently recruitin…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Alpha Radiation Emitters Device (DaRT) for the Treatment of Recurrent Glioblastoma [NA]
A clinical trial update indicates Alpha Tau Medical's DaRT alpha radiation emitter device is being studied for recurrent glioblastoma and re…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Mental Health and Suicidality in Glioblastoma Patients in Germany
This clinical trial update indicates that recruitment is ongoing for a study examining mental health and suicidality among glioblastoma pati…