Glioblastoma
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CLINICAL_TRIALS research · 2024-05-31Clinical Trial Update: T Cells and Pembrolizumab for Recurrent and Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating pembrolizumab in combination with T cell therapy for recurrent and newly diagnosed glioblastoma. Th…
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Neoadjuvant Radio-chemotherapy Safety Pilot Study in Patients With Glioblastoma [Phase 1]
A Phase 1 neoadjuvant radiochemotherapy safety pilot study for glioblastoma is currently recruiting at Hospital Universitario San Carlos in …
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Advanced MR Imaging as Predictor of Treatment Response in Newly Diagnosed Glioblastomas [NA]
Clinical trial evaluating advanced MRI techniques as predictors of treatment response in newly diagnosed glioblastoma.
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CLINICAL_TRIALS research · 2024-05-10Clinical Trial Update: Glutamate Inhibitors in Glioblastoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial conducted by the University of Zurich is evaluating glutamate inhibitors in patients with glioblastoma and is cur…
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: Escalated Dose Proton Therapy Within the Multimodality Treatment of Glioblastoma Patients [NA]
Update on a clinical trial investigating escalated-dose proton therapy as part of multimodality treatment for glioblastoma.
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Pembrolizumab for Newly Diagnosed Glioblastoma [Phase 2]
An active Phase 2 clinical trial is evaluating pembrolizumab for newly diagnosed glioblastoma, currently not recruiting.
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Glioblastoma Targeted Treatment Option Maximization by WGS [NA]
A clinical trial at UMC Utrecht is exploring whole-genome sequencing–guided, targeted treatment options for glioblastoma and is currently re…
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CLINICAL_TRIALS research · 2024-05-02Clinical Trial Update: Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant Glioma [EARLY_Phase 1]
This entry describes an early-stage Phase 1 clinical study evaluating allogeneic Vγ9Vδ2 T cells for malignant gliomas, including glioblastom…
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CLINICAL_TRIALS research · 2024-05-02Clinical Trial Update: A Trial of Neoadjuvant Therapy in Patients With Newly Diagnosed Glioblastoma [Phase 2]
A Phase 2 neoadjuvant therapy trial for newly diagnosed glioblastoma has been terminated.
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CLINICAL_TRIALS research · 2024-04-26Clinical Trial Update: Recurrent GBM Treated With Neurosurgical Resection and IORT Using the Xoft Axxent eBx System and Bevacizumab [Phase 2]
A Phase 2 clinical trial evaluating neurosurgical resection followed by intraoperative radiotherapy using the Xoft Axxent eBx System in comb…
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CLINICAL_TRIALS research · 2023-08-01Clinical Trial Update: Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their Caregivers [NA]
Feasibility and preliminary efficacy study of a mindfulness-based intervention for children and young adults with high-grade or high-risk ca…
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CLINICAL_TRIALS research · 2019-10-21Clinical Trial Update: Ceritinib Rare Indications Study in ALK+ Tumors [Phase 2]
Phase 2 trial update for ceritinib in ALK-altered tumors including anaplastic large cell lymphoma and related conditions; study terminated w…
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CLINICAL_TRIALS research · 2019-01-17Clinical Trial Update: Study of Tissue and Blood Samples From Patients With High-Grade Glioma
A completed clinical trial update describing the collection of tissue and blood samples from patients with high-grade glioma to study biolog…
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CLINICAL_TRIALS research · 2018-06-07Clinical Trial Update: Early-Phase Study to Assess Inhibitor Ribociclib in Patients With Recurrent Glioblastoma or Anaplastic Glioma [Phase 1]
Phase 1 clinical trial update evaluating the CDK4/6 inhibitor ribociclib in patients with recurrent glioblastoma or anaplastic glioma.
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CLINICAL_TRIALS research · 2018-05-11Clinical Trial Update: BIRN (Biomedical Informatics Research Network) Resources Facilitate the Personalization of Malignant Brain Tumor
This clinical trial update discusses how BIRN resources support personalizing treatment for malignant brain tumors, including glioblastoma. …
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CLINICAL_TRIALS research · 2017-12-13Clinical Trial Update: FET-PET and Multiparametric MRI for High-grade Glioma Patients Undergoing Radiotherapy
A clinical trial update from University Hospital, Brest describes evaluating FET-PET imaging and multiparametric MRI to guide radiotherapy i…
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CLINICAL_TRIALS research · 2017-12-11Clinical Trial Update: PET/CT Evaluation of Primary and Metastatic Brain Tumors With a Novel Radioiodinated Phospholipid Ether Analogue I-NM404 [NA]
Clinical trial evaluating PET/CT imaging using I-NM404 for glioblastoma multiforme and brain metastases; study completed with results posted…
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CLINICAL_TRIALS research · 2017-10-25Clinical Trial Update: Retrospective Evaluation of Melanocortin Receptor 4 Polymorphisms in Patients With GBM Treated With Radiochemotherapy
This study retrospectively examined melanocortin-4 receptor polymorphisms in glioblastoma patients treated with radiochemotherapy.
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CLINICAL_TRIALS research · 2017-10-12Clinical Trial Update: Image-derived Prediction of Response to Chemo-radiation in Glioblastoma
Clinical trial update indicating termination of a study evaluating image-derived prediction of response to chemo-radiation in glioblastoma.
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CLINICAL_TRIALS research · 2017-10-12Clinical Trial Update: Proteome-based Personalized Immunotherapy of Glioblastoma [Phase 2, Phase 3]
This document notes an ongoing Phase 2/Phase 3 trial of proteome-based personalized immunotherapy for glioblastoma, with the current status …
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CLINICAL_TRIALS research · 2017-07-24Clinical Trial Update: Application of Proteome Profiler Antibody Arrays to Find Angiogenetic Predictors in Glioma Paitents.
This clinical trial update describes using Proteome Profiler Antibody Arrays to identify angiogenesis-related predictors in glioblastoma.
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CLINICAL_TRIALS research · 2017-07-21Clinical Trial Update: Simultaneous Integrated Boost in Malignant Glioma Patients Treated With Chemoradiation [NA]
This is a clinical trial update evaluating simultaneous integrated boost with chemoradiation for glioblastoma. The sponsor is Taichung Veter…
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CLINICAL_TRIALS research · 2017-06-08Clinical Trial Update: The Efficacy of APT Magnetic Resonance Imaging in Predicting the Efficacy of Bevacizumab in Recurrent Malignant Gliomas
This document reports an update on using APT MRI to predict Bevacizumab efficacy in patients with recurrent malignant gliomas; the trial sta…
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CLINICAL_TRIALS research · 2017-05-17Clinical Trial Update: Stress, Exercise Behavior and Survival in Patients With Newly Diagnosed Glioblastoma and in a Close Partner
This clinical trial update describes a study evaluating stress and exercise behavior and survival in patients with newly diagnosed glioblast…
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CLINICAL_TRIALS research · 2017-03-22Clinical Trial Update: Disease Progression and Treatment-induced Alterations in Glioblastoma
An update on a glioblastoma clinical trial sponsored by the Medical University of Vienna, focusing on disease progression and treatment-indu…