Glioblastoma
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CLINICAL_TRIALS research · 2025-03-03Clinical Trial Update: Response Assessment During MR-guided Radiation Therapy for Glioblastoma
Recruitment is ongoing for a study evaluating response assessment during MR-guided radiation therapy in glioblastoma.
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Study of Pamiparib in Newly Diagnosed and rGBM [EARLY_Phase 1]
An early-phase study evaluating pamiparib in newly diagnosed and recurrent glioblastoma is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG [EARLY_Phase 1]
An early-phase (Phase 1) clinical trial is evaluating superselective intra-arterial cerebral infusion of temsirolimus for high-grade glioma,…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: Verteporfin for the Treatment of Recurrent High Grade EGFR-Mutated Glioblastoma [Phase 1, Phase 2]
Clinical trial update for Verteporfin in recurrent high-grade EGFR-mutated glioblastoma (Phase 1/2) is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: CSF Proteomic Characterization of Glioblastomas
A CSF proteomic characterization study in glioblastoma is listed, with the trial currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Ex VIvo DEtermiNed Cancer Therapy
An ongoing clinical trial for an Ex Vivo Determined Cancer Therapy is currently recruiting and spans multiple cancers, including bladder and…
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: Study of Olutasidenib and Temozolomide in HGG [Phase 2]
Phase 2 study evaluating olutasidenib in combination with temozolomide for high-grade gliomas is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Insights Into the Pathophysiology of Neurovascular Uncoupling in Patients with Brain Lesions. [NA]
A ClinicalTrials.gov study is currently recruiting to investigate neurovascular uncoupling in patients with brain lesions. The study involve…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Clinical Study of Carbon Ion Radiotherapy for High-grade Glioma [NA]
The trial is currently recruiting to evaluate carbon ion radiotherapy for high-grade glioma (heavy ion radiotherapy).
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Trial of Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccine [Phase 1]
A Phase 1 trial of the Heat Shock Protein Peptide Complex-96 (HSPPC-96) vaccine for glioblastoma and related CNS tumors was terminated. The …
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: Study Evaluating the Efficacy of Radiotherapy With SIB-IMRT, Associated With Temozolomide in Glioblastomas [NA]
A clinical trial evaluating the efficacy of radiotherapy with SIB-IMRT in combination with temozolomide for adult glioblastoma, currently no…
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CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: AGuIX Nanoparticles With Radiotherapy Plus Concomitant Temozolomide in the Treatment of Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
Clinical trial update for AGuIX nanoparticles combined with radiotherapy and concomitant temozolomide in newly diagnosed glioblastoma; a Pha…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: PTCs-based Precision Treatment Strategy on Recurrent High-grade Gliomas [EARLY_Phase 1]
Update on an early-phase trial investigating a PTCs-based precision treatment strategy for recurrent high-grade glioma.
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: Safety and Efficacy Study for DC Vaccine in Recurrent or Progressive High-grade Gliomas [Phase 1]
Phase 1 safety and efficacy study of a dendritic cell (DC) vaccine for recurrent or progressive high-grade gliomas (WHO grade III and IV) in…
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CLINICAL_TRIALS research · 2025-01-31Clinical Trial Update: Imaging and Biological Markers for Prediction and Identification of Glioblastoma Pseudoprogression: a Prospective Study. [NA]
A prospective study evaluating imaging techniques and biological markers to predict and identify pseudoprogression in glioblastoma, currentl…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: Advanced Diffusion MRI to Differentiate Tumor Recurrence From Pseudoprogression in Patients With Glioblastoma and Brain Metastases [NA]
This clinical trial update describes a study using advanced diffusion MRI to differentiate tumor recurrence from pseudoprogression in gliobl…
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: Impact of Salovum® and SPC® Flakes on Brain Tumor Induced Edema [Phase 2]
A Phase 2 clinical trial update evaluating Salovum and SPC Flakes for brain tumor–induced edema in glioblastoma, cerebral metastases, and me…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Vebreltinib Combined With Temozolomide for Glioblastoma (GBM) After Surgery [Phase 2]
Phase 2 clinical trial evaluating Vebreltinib with Temozolomide for glioblastoma after surgery; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Drug Response Testing and Repurposing Using Glioblastoma Organoid
A study is recruiting to test drug responses using glioblastoma organoids. The aim is to repurpose existing drugs based on organoid response…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: A Clinical Trial on Combined (Neo-)Adjuvant Intravenous Plus Intracranial Administration of Ipilimumab and Nivolumab in Recurrent Glioblastoma [Phase 1]
A Phase 1 trial is evaluating combined intravenous plus intracranial administration of ipilimumab and nivolumab in patients with Glioblastom…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Expanded Access Program for GBM Subjects
This update notes an expanded access program for glioblastoma patients sponsored by Rznomics, Inc., and it is currently available for eligib…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Evaluation of in Vitro Antitumor Activity of GD2 CAR-T Cells in Glioblastoma [NA]
Preclinical in vitro study evaluating the antitumor activity of GD2-targeted CAR-T cells against glioblastoma.
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CLINICAL_TRIALS research · 2025-01-03Clinical Trial Update: Safety and Efficacy of NRG-103 Injection in the Treatment of Recurrent Glioblastoma Patients [EARLY_Phase 1]
This is an early Phase 1 clinical trial registry entry evaluating the safety and efficacy of NRG-103 Injection for recurrent glioblastoma, w…
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: Hypofractionated Radiotherapy [NA]
A clinical trial evaluating hypofractionated radiotherapy for glioblastoma is currently recruiting, sponsored by The First Hospital of Jilin…
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: Nivolumab and Temozolomide Versus Temozolomide Alone in Newly Diagnosed Elderly Patients With GBM [Phase 2]
Clinical trial update for a Phase 2 study comparing nivolumab plus temozolomide versus temozolomide alone in newly diagnosed elderly patient…