Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults [Phase 1]
Phase 1 clinical trial evaluating immunotherapy before and after surgery for recurrent or progressive high-grade glioma in children and youn…
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: A Phase 1b / 2 Drug Resistant Immunotherapy With Activated, Gene Modified Allogeneic or Autologous γδ T Cells (DeltEx) in Combination With Maintenance Temozolomide in Subjects With Recurrent or Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
This clinical trial update covers a Phase 1b/2 study evaluating DeltEx, an activated, gene-modified γδ T cell therapy, in combination with m…
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: 5G-EMERALD: Amivantamab in Malignant Brain Tumours [Phase 1]
A Phase 1 clinical trial of amivantamab for malignant brain tumors, including glioblastoma and related gliomas, is currently recruiting in t…
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: Enhanced Adjuvant Therapy for Newly Diagnosed GBM With Partial Surgical Resection or Short-term Progression [Phase 2]
A Phase 2 clinical trial update on enhanced adjuvant therapy for newly diagnosed glioblastoma with partial surgical resection or short-term …
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: Research on the Safety and Efficacy of Intraoperative Radiation Therapy in Malignant Cerebral Tumor [NA]
This entry describes a clinical trial evaluating intraoperative radiation therapy for malignant brain tumors, including glioblastoma, which …
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: DC Migration Study to Evaluate TReg Depletion In GBM Patients With and Without Varlilumab [Phase 2]
A Phase 2 clinical trial update describes a study evaluating dendritic cell migration and regulatory T cell depletion in glioblastoma patien…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: A Study of Chlorophyllin for the Management of Brain Radio-necrosis in Patients With Diffuse Glioma [Phase 2]
Phase 2 clinical trial evaluating chlorophyllin for the management of brain radionecrosis in patients with diffuse glioma is currently recru…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: TTFields General Routine Clinical Care in ndGBM Patients: a French Prospective Non-Interventional Study (TIGER France)
A French prospective non-interventional study (TIGER France) is assessing general routine TTFields care in newly diagnosed glioblastoma pati…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Injection of Active Allogeneic Natural Killer Cells in Patients With Gliomas [Phase 2]
A Phase 2 clinical trial evaluating injections of active allogeneic natural killer cells in patients with gliomas is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
A clinical trial update describes ongoing Phase 1/2 studies evaluating super-selective intra-arterial repeated infusion of cetuximab for new…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM [Phase 1, Phase 2]
Clinical trial update announcing ongoing Phase 1/Phase 2 study of the CAPTEM regimen (capecitabine plus temozolomide) for newly diagnosed gl…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM) [Phase 1]
A Phase 1 clinical trial investigating a laparoscopically harvested omental autograft to bypass the blood-brain barrier in recurrent gliobla…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating repeated super-selective intraarterial infusion of bevacizumab (Avastin) for relapsed glioblastoma …
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: First-in-human Trial of PhOx430, a First-in-class Acetylglucosaminyltransferase V Inhibitor, in Advanced Solid Tumours [Phase 1]
First-in-human Phase 1 trial of PhOx430, a first-in-class Acetylglucosaminyltransferase V inhibitor, assessed in advanced solid tumors; the …
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Development and Implementation of an Intervention Enhancing Involvement of Relatives to Patients With Acquired Brain Injury or Malignant Brain Tumour
This clinical trial update describes the development and implementation of an intervention aimed at enhancing involvement of relatives for p…
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Immuno-Positron Emission Tomography (PET)-Glioma Study, a Proof-of-principle Imaging Study [NA]
A proof-of-principle immuno-PET imaging study in glioblastoma, currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Clinical Trial Assessing the Efficacy and Safety of Dendritic Cell-Based Immunotherapy for Glioblastoma [Phase 3]
Phase 3 clinical trial evaluating dendritic cell-based immunotherapy for glioblastoma, currently not recruiting.
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Radioimmunotherapy with Lu-177 Labeled 6A10 Fab-fragments in Patients with Glioblastoma After Standard Treatment [Phase 1]
Phase 1 clinical trial evaluating Lu-177 labeled 6A10 Fab fragments for glioblastoma after standard treatment. The study is currently recrui…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138) [NA]
This clinical trial update describes an ongoing study evaluating Laser Interstitial Thermal Therapy (LITT) followed by hypofractionated radi…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Patient's Derived Organoids for Drug Screening in Glioblastoma [NA]
The study aims to use patient-derived glioblastoma organoids to screen potential drugs, with the trial currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: A Phase I Clinical Study of Intratumoral Injection GC001 in Patient With Recurrent or Progressive Gliomas [Phase 1]
Phase I study of intratumoral GC001 in patients with recurrent or progressive high-grade gliomas is currently recruiting.
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Stem Cell Analysis, Omics (Including Immunomics) and Artificial Intelligence in Glioblastoma [NA]
This clinical trial registry entry describes a study applying stem cell analysis, multi-omics, and artificial intelligence to glioblastoma (…
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: Study to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM Subjects [Phase 1, Phase 2]
A Phase 1/2 study evaluating the GBM vaccine VBI-1901 for safety, tolerability, and dose optimization in recurrent glioblastoma is currently…
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: A Study to Evaluate Safety and Efficacy of BEY1107 in Combination with Temozolomide in Patients with Recurrent or Progressive Glioblastoma Multiforme (GBM) [Phase 1]
Phase 1 clinical trial evaluating BEY1107 in combination with temozolomide for recurrent or progressive glioblastoma multiforme; currently r…
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: Study of LP-184 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
Lantern Pharma's LP-184 is being studied in a phase 1/2 trial for advanced and metastatic solid tumors, with indications including glioblast…