Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: A Phase II Clinical Study to Evaluate the Efficacy and Safety of Flazoparib Combined With Temozolomide After the Completion of Standard Concurrent Chemoradiotherapy (CCRT) in Newly Diagnosed Glioblastoma [Phase 2]
Phase II clinical study assessing the efficacy and safety of combining flazoparib with temozolomide after standard chemoradiotherapy in newl…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM) [Phase 2, Phase 3]
A Phase 2/3 clinical trial of a neoantigen-specific adoptive T cell therapy for newly diagnosed MGMT-negative glioblastoma multiforme, spons…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Study Using Genomic, Histologic and Radiomic Analysis to Evaluate Regional Tumor Heterogeneity in Patients Undergoing Surgery for Newly Diagnosed Glioblastoma
This clinical trial update indicates that the study evaluating genomic, histologic, and radiomic analysis of regional tumor heterogeneity in…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors [Phase 2]
Phase 2 study evaluating APL-101 in non-small cell lung cancer with MET exon 14 skipping mutations and MET dysregulation, as well as other M…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma [Phase 1]
This is a Phase 1 clinical trial evaluating intracranial TGFβR2KO/IL13Rα2 CAR T-cells for recurrent glioblastoma and IDH-mutant astrocytoma …
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma [Phase 1]
Phase 1 clinical trial update evaluating intrathecal azacitidine in combination with nivolumab for recurrent high-grade glioma. The study is…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Glioblastoma Treatment With Irradiation and Olaptesed Pegol (NOX-A12) in MGMT Unmethylated Patients [Phase 1, Phase 2]
Phase 1/Phase 2 trial evaluating irradiation with olaptesed pegol (NOX-A12) in MGMT unmethylated glioblastoma; the study is currently active…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma [Phase 1]
Phase 1 trial evaluating the combination of eflornithine and temozolomide in newly diagnosed glioblastoma or astrocytoma; recruitment is ong…
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: Feasibility of ORGAnoids in Routine Clinical Practice for Molecular Analysis of the GLIOvascular Niche in Patients With Primary Brain Tumors. [NA]
This clinical trial update assesses the feasibility of using patient-derived organoids for routine molecular analysis of the gliovascular ni…
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: Clinical Trial of BMS-986504 in Recurrent GBM Patients [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating BMS-986504 in patients with recurrent glioblastoma (WHO Grade IV) is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Short Course Chemo-Radiation Therapy for Patients With Newly Diagnosed Glioblastoma [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial is evaluating a short-course chemo-radiation regimen for newly diagnosed glioblastoma; the study is current…
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Personalized Radiation Therapy for GBM [NA]
Ongoing trial update for personalized radiation therapy in glioblastoma, with the study currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Anterior Temporal Lobectomy in Temporal Glioblastoma [Phase 3]
A Phase 3 clinical trial is evaluating anterior temporal lobectomy as a surgical treatment for newly diagnosed glioblastoma of the temporal …
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Hitting the Mark: Introducing State-of-the-art MRI for Precision Radiotherapy of Glioblastoma [NA]
A clinical trial at Erasmus Medical Center is recruiting to evaluate a state-of-the-art MRI-guided precision radiotherapy approach for gliob…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Glutamate Excitotoxicity and Its Role in Glioblastoma Biology
A clinical trial investigating the role of glutamate excitotoxicity in glioblastoma biology is currently recruiting, sponsored by IRCCS San …
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma [Phase 1]
Phase 1 study evaluating the safety and tolerability of Fb-PMT in patients with recurrent glioblastoma, with recruitment ongoing.
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) in Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma [Phase 2]
This entry describes a Phase 2 trial evaluating DB107-Retroviral Replicating Vector (RRV) in combination with DB107-Flucytosine for recurren…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Safety, Pharmacokinetics and Preliminary Efficacy of CS231295 in Advanced Solid Tumors [Phase 1]
A Phase 1 trial from Chipscreen Biosciences assesses safety, pharmacokinetics, and preliminary efficacy of CS231295 in adults with advanced …
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Disulfiram/Copper Combination In The Treatment of Newly Diagnosed Glioblastoma Multiform [Phase 2]
This update describes a Phase 2 clinical trial evaluating a disulfiram/copper combination for newly diagnosed glioblastoma.
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CLINICAL_TRIALS research · 2025-05-21Clinical Trial Update: Conventional Versus Hypofractionated Radiotherapy With Temozolomide in Elderly Glioblastoma [Phase 3]
A Phase 3 trial comparing conventional versus hypofractionated radiotherapy with temozolomide in elderly glioblastoma patients is currently …
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Phase I/II Study of Pazopanib+ Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme [Phase 1, Phase 2]
Phase I/II trial updating the combination of pazopanib and temozolomide for newly diagnosed glioblastoma multiforme, currently recruiting.
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Personalized Cancer Stem Cell High-Throughput Drug Screening for Glioblastoma [EARLY_Phase 1]
An early-phase 1 clinical trial at Swedish Medical Center is exploring personalized cancer stem cell high-throughput drug screening for newl…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) in Glioma (WHO G3-G4) Progression [NA]
This entry notes that recruitment is ongoing for a local alpha-emitter therapy, [225Ac]Ac-DOTA-SP (TAT), being studied for glioblastoma and …
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Temozolomide, Radiation Therapy, and Tumor Treating Fields Therapy in Treating Participants With Glioblastoma [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating Temozolomide in combination with radiation therapy and Tumor Treating Fields Therapy for glioblas…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: A Study of BL-B01D1 in Patients With Recurrent Glioblastoma [Phase 2]
Phase 2 clinical trial update for BL-B01D1 in recurrent glioblastoma; the study is currently recruiting.