Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Magnetic Resonance Fingerprinting Guided Extended Resection in Glioblastomas [Phase 1]
Phase 1 trial using magnetic resonance fingerprinting to guide extended surgical resection in patients with glioblastoma; the study is not y…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: IA Carboplatin + Radiotherapy in Relapsing GBM [Phase 1, Phase 2]
Clinical trial evaluating intra-arterial carboplatin with radiotherapy for relapsed glioblastoma, currently recruiting for Phase 1/Phase 2.
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: PH Sensitive MRI Based Resections of Glioblastoma [Phase 1]
Phase 1 clinical trial evaluating pH-sensitive MRI-guided resections for glioblastoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: A Phase 2 and Pharmacodynamic Study of Sitagliptin in Patients With Progressive Grade 4 Gliomas [Phase 2]
A Phase 2 pharmacodynamic study of sitagliptin is planned for patients with progressive grade 4 gliomas, and the trial is currently recruiti…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Physiological MRI for Precision Radiotherapy IDH-wildtype Glioblastoma [NA]
A clinical trial at Erasmus Medical Center is active but not recruiting, evaluating physiological MRI to guide precision radiotherapy for ID…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Feasibility of ONCOhabitats for Surgical and Treatment Planning in IDH-Wildtype Glioblastoma (SINUE)
Clinical trial update showing recruitment for a study to evaluate the feasibility of ONCOhabitats to aid surgical and treatment planning in …
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Prognostic IntraOperative Biomarkers ideNtification in Tumor rElatEd suRgery [NA]
A ClinicalTrials.gov listing for a study at Erasmus Medical Center evaluating intraoperative biomarkers to predict prognosis during tumor-re…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Intraarterial Carboplatin + Caelyx vs Intraarterial Carboplatin + Etoposide Phosphate for Progressing Glioblastoma [Phase 2]
A Phase 2 clinical trial comparing intraarterial carboplatin plus Caelyx to intraarterial carboplatin plus etoposide phosphate for progressi…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant Glioma [Phase 1]
This is a Phase Ib dose-escalation trial evaluating intratumoral administration of IRS-1 HSV C134 in patients with recurrent malignant gliom…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Spectroscopic MRI, Proton Therapy, and Avastin for Recurrent Glioblastoma [NA]
This University of Miami trial is evaluating spectroscopic MRI, proton therapy, and bevacizumab (Avastin) for recurrent glioblastoma and is …
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Study of Metabolic, Transcriptomic and Proteomic Characteristics in Relapsed Glioblastoma
A recruiting study at University Hospital, Bordeaux aims to characterize metabolic, transcriptomic, and proteomic features of relapsed gliob…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Translational Study of Nivolumab in Combination With Bevacizumab for Recurrent Glioblastoma [Phase 2]
This clinical trial update reports a Phase 2 translational study of nivolumab in combination with bevacizumab for recurrent glioblastoma. Th…
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: CART-EGFR-IL13Ra2 in Newly Diagnosed GBM Following Initial Radiotherapy [Phase 1]
This entry reports a Phase 1 clinical trial at the University of Pennsylvania evaluating CART-EGFR-IL13Ra2 CAR-T cells following initial rad…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Implantable Microdevice In Primary Brain Tumors [EARLY_Phase 1]
An early Phase 1 clinical trial evaluating an implantable microdevice for primary brain tumors is currently recruiting across multiple gliom…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Vaccination With Autologous Dendritic Cells Loaded With Autologous Tumour Homogenate in Glioblastoma [Phase 2]
This clinical trial update describes a Phase 2 study evaluating vaccination with autologous dendritic cells loaded with autologous tumor hom…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Clinical Evaluation of [68Ga]Ga-XT771 PET for Diagnosis in Patients With Glioblastoma and Clear Cell Renal Cell Carcinoma [EARLY_Phase 1]
Early-phase clinical trial evaluating the diagnostic PET tracer [68Ga]Ga-XT771 for glioblastoma and clear cell renal cell carcinoma, current…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma [NA]
A clinical trial update describes using molecular profiling to tailor treatments for patients with high-grade glioma, aiming to improve indi…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Fimepinostat in Treating Brain Tumors in Children and Young Adults [EARLY_Phase 1]
This is an early-phase 1 trial update on fimepinostat for pediatric and young adult brain tumors, including DIPG, recurrent anaplastic astro…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: The Effect of Glioblastoma PSMA Expression Following Tumour VEGF Blockade From Bevacizumab
A clinical trial investigating PSMA expression in glioblastoma after VEGF blockade with bevacizumab is currently NOT_YET_RECRUITING. The stu…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: IL13Ra2-CAR T Cells With or Without Nivolumab and Ipilimumab in Treating Patients With GBM [Phase 1]
Phase 1 trial evaluating IL13Ra2-CAR T cells with or without nivolumab and ipilimumab in recurrent glioblastoma, currently recruiting.
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Loupe-Based Intraoperative Fluorescence Imaging
Clinical trial update on loupe-based intraoperative fluorescence imaging for brain tumors; recruitment is ongoing for glioblastoma and anapl…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: BC008-1A Injection for Recurrent CNS WHO G4 Glioma [Phase 1]
A Phase 1 study of BC008-1A Injection for recurrent central nervous system WHO Grade 4 glioma (including glioblastoma) is currently recruiti…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Restrictive Use of Dexamethasone in Glioblastoma [NA]
This clinical trial update notes a study evaluating the restrictive use of dexamethasone in glioblastoma patients, currently recruiting.
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Prognostic Potential of Olfactory Function in Glioblastoma: a Prospective Observational Study
This prospective observational study investigates whether olfactory function can serve as a prognostic indicator in adults with glioblastoma…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Adaptive Radiotherapy and MRIs Based on Patients With Newly Diagnosed High-Grade Glioma [NA]
This Columbia University trial assesses adaptive radiotherapy guided by MRI for adults with newly diagnosed high-grade glioma, including gli…