Glioblastoma Multiforme
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-10-27Clinical Trial Update: Gliadel Wafers and Temodar in the Treatment of Glioblastoma Multiforme [Phase 2]
A Phase 2 trial evaluating Gliadel wafers in combination with temozolomide (Temodar) for primary glioblastoma multiforme has been terminated…
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CLINICAL_TRIALS trial_result · 2016-10-21Clinical Trial Update: Evaluation of FDOPA-PET/MRI in Pediatric Patients With CNS Tumors [Phase 1]
Phase 1 trial evaluating FDOPA-PET/MRI imaging in pediatric CNS tumors has completed the Phase 1 portion.
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CLINICAL_TRIALS trial_result · 2016-10-19Clinical Trial Update: Pilot Study of Autologous Chimeric Switch Receptor Modified T Cells in Recurrent Glioblastoma Multiforme [Phase 1]
Phase 1 pilot trial evaluating autologous chimeric switch receptor-modified T cells for recurrent glioblastoma multiforme.
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CLINICAL_TRIALS trial_result · 2016-10-17Clinical Trial Update: Vaccine Therapy in Treating Patients Undergoing Surgery for Recurrent Glioblastoma Multiforme [Phase 1]
Phase 1 trial of a vaccine therapy for patients undergoing surgery for recurrent glioblastoma multiforme has completed.
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CLINICAL_TRIALS trial_result · 2016-10-17Clinical Trial Update: INTRAGO-Intraoperative Radiotherapy for Glioblastoma - a Phase I/II Study [Phase 1, Phase 2]
The INTRAGO trial investigates intraoperative radiotherapy for glioblastoma in a Phase I/II study. The study status is completed.
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CLINICAL_TRIALS trial_result · 2016-06-06Clinical Trial Update: A Phase I Study to Investigate Tolerability and Efficacy of ALECSAT Administered to Glioblastoma Multiforme Patients [Phase 1]
Phase I trial of ALECSAT in glioblastoma multiforme patients has completed, assessing tolerability and preliminary efficacy.
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CLINICAL_TRIALS trial_result · 2016-06-06Clinical Trial Update: Randomized Phase 2 Study to Investigate Efficacy of ALECSAT in Patients With GBM Measured Compared to Avastin/Irinotecan [Phase 2]
A randomized Phase 2 study evaluating ALECSAT in glioblastoma multiforme compared to Avastin/irinotecan has been terminated.
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CLINICAL_TRIALS trial_result · 2016-06-03Clinical Trial Update: Dose Evaluation Safety STudy IN Individuals With Astrocytoma Taking PolyMVA [Phase 1]
Phase 1 dose-evaluation safety study of PolyMVA in individuals with glioblastoma multiforme (grade IV astrocytoma) has completed.
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FDA approval · 2016-04-28FDA Approved: CARMUSTINE — Supplemental Application (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.)
The FDA approved a supplemental application for Carmustine submitted by Heritage Pharmaceuticals Inc. (doing business as Avet Pharmaceutical…
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: Trial of Temozolomide, Bevacizumab Plus Bortezomib for Recurrent Glioblastoma Multiforme [Phase 1]
Phase 1 trial evaluating a combination of temozolomide, bevacizumab, and bortezomib in recurrent glioblastoma multiforme has completed enrol…
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FDA approval · 2016-04-27FDA Approved: TEMOZOLOMIDE — Original Application (Rising Pharma Holdings, Inc.)
FDA approved the original application for temozolomide in a generic form, enabling Rising Pharma Holdings, Inc. to market temozolomide.
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CLINICAL_TRIALS trial_result · 2016-04-15Clinical Trial Update: AMG 595 First-in-Human in Recurrent Gliomas [Phase 1]
Amgen completed a first-in-human Phase 1 trial of AMG 595 in recurrent gliomas to assess safety and early signals of activity. The study inc…
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme [Phase 1, Phase 2]
ClinicalTrials.gov indicates a completed Phase 1/2 study evaluating cilengitide with temozolomide and radiation for newly diagnosed glioblas…
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CLINICAL_TRIALS trial_result · 2016-02-19Clinical Trial Update: Iodine I 131 Monoclonal Antibody TNT-1/B in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme [Phase 1]
This ClinicalTrials.gov entry reports the completion of a Phase 1 study evaluating the iodine-131 labeled monoclonal antibody TNT-1/B for pr…
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CLINICAL_TRIALS trial_result · 2016-02-10Clinical Trial Update: Oral Tarceva Study for Recurrent/Residual Glioblastoma Multiforme and Anaplastic Astrocytoma [Phase 1, Phase 2]
This update reports results from a Phase 1/2 trial of Tarceva (erlotinib) for recurrent/residual glioblastoma multiforme and anaplastic astr…
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CLINICAL_TRIALS trial_result · 2016-01-21Clinical Trial Update: Chemotherapy, Radiation Therapy, and Vaccine Therapy With Basiliximab in Treating Patients With Glioblastoma Multiforme That Has Been Removed by Surgery [Phase 1]
Phase 1 trial evaluating chemotherapy, radiation therapy, and basiliximab-based vaccine therapy for glioblastoma multiforme after surgical d…
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CLINICAL_TRIALS trial_result · 2015-11-10Clinical Trial Update: Study of AEE788 in Patients With Recurrent/Relapse Glioblastoma Multiforme (GBM) [Phase 1, Phase 2]
This clinical trial update reports the completed Phase 1/Phase 2 study of AEE788 in patients with recurrent or relapsed glioblastoma multifo…
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CLINICAL_TRIALS trial_result · 2015-10-05Clinical Trial Update: Radiosurgery for Glioblastoma Multiforme [Phase 1, Phase 2]
Phase 1/2 trial evaluating radiosurgery for glioblastoma multiforme was terminated; results were posted in 2015.
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FDA approval · 2015-09-18FDA Approved: TEMODAR — Supplemental Application (Merck Sharp & Dohme LLC)
FDA approved a supplemental application for TEMODAR (temozolomide) submitted by Merck Sharp & Dohme LLC. The action updates the drug's label…
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CLINICAL_TRIALS trial_result · 2015-06-18Clinical Trial Update: Effect of Deep TMS on the Permeability of the BBB in Patients With Glioblastoma Multiforme: a Pilot Study [Phase 2]
A Phase 2 pilot trial evaluated whether deep repetitive transcranial magnetic stimulation (Deep TMS) can affect blood-brain barrier permeabi…
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CLINICAL_TRIALS trial_result · 2015-06-17Clinical Trial Update: BrUOG 263: Prostate Specific Membrane Antigen (PSMA) Glioblastoma Multiforme (GBM) [Phase 2]
Phase 2 trial update for PSMA-targeted approach in glioblastoma multiforme (GBM) showing completed results as of 2015.
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CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: PPX and Concurrent Radiation for Newly Diagnosed Glioblastoma Without MGMT Methylation [Phase 2]
Phase 2 trial updating outcomes for PPX with concurrent radiation in newly diagnosed glioblastoma patients without MGMT methylation.
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: Vorinostat, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme [Phase 1, Phase 2]
Clinical trial evaluating vorinostat with temozolomide and radiation for newly diagnosed glioblastoma multiforme has completed (Phase 1/2).
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FDA approval · 2015-05-08FDA Approved: TEMOZOLOMIDE — Original Application (Amneal Pharmaceuticals LLC)
FDA approved Amneal Pharmaceuticals LLC's Original Application for temozolomide (generic temozolomide), authorizing its marketed generic pro…
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CLINICAL_TRIALS trial_result · 2015-04-28Clinical Trial Update: Cilengitide and Sunitinib Malate in Treating Patients With Advanced Solid Tumors or Glioblastoma Multiforme [Phase 1]
A Phase 1 study evaluating cilengitide in combination with sunitinib malate in adults with advanced solid tumors or glioblastoma multiforme …