Glioblastoma Multiforme
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Immunogene-modified T (IgT) Cells Against Glioblastoma Multiforme [Phase 1]
Phase 1 clinical trial evaluating immunogene-modified T (IgT) cells for glioblastoma multiforme; currently enrolling by invitation.
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1) [Phase 1]
Phase 1 study evaluating re-administration of C134 in patients with recurrent glioblastoma and related brain gliomas has been terminated.
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme [Phase 2]
Phase 2 trial update for glioblastoma multiforme evaluating Subventricular Zone-targeted therapy in combination with temozolomide; the study…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Neuro-pharmacological Properties of Repurposed Posaconazole in Glioblastoma: A Phase 0 Clinical Trial [EARLY_Phase 1]
This document reports the termination of a Phase 0/early Phase 1 trial evaluating repurposed posaconazole for glioblastoma, with results pos…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: 11C-methionine in Diagnostics and Management of Glioblastoma Multiforme Patients (GlioMET) [Phase 2]
Phase 2 clinical trial evaluating 11C-methionine for diagnostics and management of glioblastoma multiforme has completed.
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: G-CSF After Chemo-radiation in Patients With Glioblastoma [Phase 2]
This document reports a Phase 2 clinical trial evaluating the use of granulocyte colony-stimulating factor (G-CSF) after chemotherapy and ra…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Trial of Dichloroacetate (DCA) in Glioblastoma Multiforme (GBM) [Phase 2]
Phase 2 clinical trial evaluating dichloroacetate (DCA) for glioblastoma multiforme; the study is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-05-30Clinical Trial Update: A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection [EARLY_Phase 1]
A Phase 0/I study evaluating ribociclib in combination with everolimus in preoperative recurrent high-grade glioma patients scheduled for re…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Repeated Super-selective Intraarterial Cerebral Infusion Of Bevacizumab Plus Carboplatin For Treatment Of Relapsed/Refractory GBM And Anaplastic Astrocytoma [Phase 1, Phase 2]
A Phase 1/2 trial of repeated super-selective intraarterial bevacizumab plus carboplatin for relapsed/refractory glioblastoma multiforme and…
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CLINICAL_TRIALS trial_result · 2024-11-29Clinical Trial Update: UNIty-Based MR-Linac Guided AdapTive RadiothErapy for High GraDe Glioma: a Phase 2 Trial [NA]
The Phase 2 trial evaluating UNITY-based MR-Linac guided adaptive radiotherapy for glioblastoma multiforme has completed.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM) [NA]
This clinical trial update indicates recruitment for a study evaluating omental tissue autograft in patients with recurrent glioblastoma mul…
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CLINICAL_TRIALS trial_result · 2024-06-06Clinical Trial Update: Berubicin in Adult Patients With Recurrent Glioblastoma Multiforme (WHO Grade IV) [Phase 1, Phase 2]
This clinical trial update reports that Berubicin in adults with recurrent glioblastoma multiforme (WHO Grade IV) in Phase 1/2 was terminate…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Efficacy, Safety and CNS Exposure of G-202 (Mipsagargin) in Patients With Recurrent or Progressive Glioblastoma [Phase 2]
Phase 2 study evaluating the efficacy, safety and CNS exposure of G-202 (Mipsagargin) in patients with recurrent or progressive glioblastoma…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Lapatinib With Temozolomide and Regional Radiation Therapy for Patients With Newly-Diagnosed Glioblastoma Multiforme [Phase 2]
This Phase 2 trial update reports on combining lapatinib with temozolomide and regional radiation therapy for patients with newly diagnosed …
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: Phase 2a Study of CAN-2409 With Standard Radiation Therapy for Malignant Glioma [Phase 2]
Phase 2a study of CAN-2409 with standard radiation therapy in malignant glioma (including glioblastoma multiforme) has completed; results po…
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CLINICAL_TRIALS trial_result · 2024-03-13Clinical Trial Update: A Study of Poziotinib in Patients With Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Activating Mutations in Advanced Malignancies [Phase 2]
Phase 2 trial of poziotinib in EGFR or HER2 activating mutations across advanced malignancies was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2024-02-05Clinical Trial Update: Study of XL184 (Cabozantinib) in Adults With Glioblastoma Multiforme [Phase 2]
A Phase 2 clinical trial evaluating cabozantinib (XL184) in adults with glioblastoma multiforme has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Repeated Super-Selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Newly Diagnosed GBM [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluated repeated super-selective intraarterial infusion of bevacizumab for newly diagnosed glioblastoma multifo…
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CLINICAL_TRIALS trial_result · 2024-01-02Clinical Trial Update: Glioblastoma Multiforme (GBM) Proton vs. Intensity Modulated Radiotherapy (IMRT) [Phase 2]
Phase 2 clinical trial comparing proton therapy to intensity-modulated radiotherapy for glioblastoma multiforme has completed; results poste…
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CLINICAL_TRIALS trial_result · 2023-11-22Clinical Trial Update: Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma [Phase 2]
Phase 2 trial evaluating a Protein Phosphatase 2A inhibitor in recurrent glioblastoma and related gliomas completed, with results posted in …
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: Low Dose Radiation Therapy for Glioblastoma Multiforme [Phase 2]
Phase 2 trial update on low dose radiation therapy for high-grade glioma (glioblastoma multiforme).
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CLINICAL_TRIALS trial_result · 2023-06-28Clinical Trial Update: TTFields and Radiosurgery of Recurrent Glioblastoma +/- 18F-Fluoro-Ethyl-Thyrosine [Phase 2]
Phase 2 clinical trial evaluating TTFields with radiosurgery for recurrent glioblastoma, with auxiliary imaging using 18F-Fluoro-Ethyl-Thyro…
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: Dalteparin and Radiation Therapy in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme [Phase 2]
Phase 2 clinical trial evaluating dalteparin in combination with radiation therapy for newly diagnosed supratentorial glioblastoma multiform…
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CLINICAL_TRIALS trial_result · 2023-06-15Clinical Trial Update: High-Dose Methotrexate and Leucovorin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme [Phase 2]
Phase 2 clinical trial evaluating high-dose methotrexate with leucovorin in newly diagnosed glioblastoma multiforme (brain and CNS tumors).
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CLINICAL_TRIALS trial_result · 2023-06-01Clinical Trial Update: Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma [Phase 1, Phase 2]
A Phase I/II trial evaluating TVI-Brain-1 for safety and efficacy in recurrent high-grade gliomas, including glioblastoma multiforme, has co…