Glioblastoma Multiforme
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-04-06Clinical Trial Update: Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer [Phase 1, Phase 2]
Phase 1/2 study of sacituzumab govitecan-hziy (IMMU-132) in adults with epithelial cancers; trial completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-03-01Clinical Trial Update: Bevacizumab and Temozolomide Following Radiation and Chemotherapy for Newly Diagnosed Glioblastoma Multiforme [Phase 2]
Phase 2 trial evaluating bevacizumab with temozolomide after radiation/chemotherapy in newly diagnosed glioblastoma multiforme has completed…
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CLINICAL_TRIALS trial_result · 2021-02-15Clinical Trial Update: Bevacizumab and Lomustine for Recurrent GBM [Phase 3]
Phase 3 trial evaluating bevacizumab and lomustine for recurrent glioblastoma multiforme has completed.
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CLINICAL_TRIALS trial_result · 2021-01-28Clinical Trial Update: Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma [Phase 1]
Phase 1 trial evaluating CMV RNA-pulsed dendritic cells in pediatric and young adult patients with recurrent malignant glioma and related br…
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CLINICAL_TRIALS trial_result · 2020-10-30Clinical Trial Update: Gefitinib and Radiation Therapy in Treating Patients With Glioblastoma Multiforme [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating gefitinib with radiation therapy for glioblastoma multiforme has completed.
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CLINICAL_TRIALS trial_result · 2020-10-22Clinical Trial Update: Radiation Therapy Followed by Carmustine in Treating Patients Who Have Supratentorial Glioblastoma Multiforme [Phase 2]
Phase 2 trial evaluating radiation therapy followed by carmustine for supratentorial glioblastoma multiforme; study completed.
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CLINICAL_TRIALS trial_result · 2020-10-22Clinical Trial Update: Radiation Therapy and Tamoxifen in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma Multiforme [Phase 2]
Phase 2 clinical trial evaluating radiation therapy and tamoxifen in adults with newly diagnosed supratentorial glioblastoma multiforme has …
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CLINICAL_TRIALS trial_result · 2020-09-21Clinical Trial Update: Bevacizumab, Temozolomide, and External Beam Radiation Therapy as First-Line Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma [Phase 2]
Phase 2 trial evaluating bevacizumab, temozolomide, and external beam radiotherapy as first-line therapy for newly diagnosed glioblastoma mu…
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CLINICAL_TRIALS trial_result · 2020-09-18Clinical Trial Update: Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab [Phase 2]
Phase 2 clinical trial evaluating oral pazopanib plus oral topotecan given in a metronomic antiangiogenic regimen for recurrent glioblastoma…
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FDA approval · 2020-08-13FDA Approved: TEMOZOLOMIDE — Supplemental Application (Accord Healthcare Inc.)
FDA approves Accord Healthcare Inc.'s supplemental application for temozolomide, supporting a generic version of the drug. The action corres…
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CLINICAL_TRIALS trial_result · 2020-08-06Clinical Trial Update: Phase 1/2 Study of Enzastaurin in Newly Diagnosed Glioblastoma Multiforme (GBM) and Gliosarcoma (GS) Patients [Phase 1, Phase 2]
Phase 1/2 study of enzastaurin in newly diagnosed glioblastoma multiforme and gliosarcoma completed; results posted.
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CLINICAL_TRIALS trial_result · 2020-08-03Clinical Trial Update: Sirolimus in Treating Patients With Glioblastoma Multiforme [Phase 1, Phase 2]
Clinical trial update for sirolimus in patients with glioblastoma multiforme spanning Phase 1 and Phase 2, completed.
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CLINICAL_TRIALS trial_result · 2020-07-29Clinical Trial Update: A Phase 1b/2, Multicenter, Open-label Study of ACP-196 in Subjects With Recurrent Glioblastoma Multiforme (GBM) [Phase 1, Phase 2]
Clinical trial update for ACP-196 (acalabrutinib) in recurrent glioblastoma multiforme, a phase 1b/2 open-label study; the trial status is a…
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CLINICAL_TRIALS trial_result · 2020-07-17Clinical Trial Update: Bortezomib, Temozolomide, and Regional Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma [Phase 2]
Phase 2 trial evaluating bortezomib, temozolomide, and regional radiation therapy for newly diagnosed glioblastoma multiforme or gliosarcoma…
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CLINICAL_TRIALS trial_result · 2020-04-24Clinical Trial Update: Single-Arm Open-Label Multicenter Study of VB-111 in Patients With Recurrent Glioblastoma Multiforme [Phase 1, Phase 2]
Clinical trial update for VB-111 in recurrent glioblastoma multiforme (Phase 1/Phase 2) completed.
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CLINICAL_TRIALS trial_result · 2020-03-17Clinical Trial Update: ADCTA for Adjuvant Immunotherapy in Standard Treatment of Recurrent Glioblastoma Multiforme (GBM) [Phase 3]
Phase 3 trial update for ADCTA as adjuvant immunotherapy in recurrent glioblastoma multiforme undergoing standard treatment.
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CLINICAL_TRIALS trial_result · 2020-03-12Clinical Trial Update: A Large-scale Research for Immunotherapy of Glioblastoma With Autologous Heat Shock Protein gp96 [Phase 2]
Phase 2 trial update for autologous heat shock protein gp96 immunotherapy in glioma of the brain (glioblastoma context not explicitly stated…
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CLINICAL_TRIALS trial_result · 2019-11-12Clinical Trial Update: Hyperfractionated RT With BCNU Versus Conventional RT With BCNU for Supratentorial Malignant Glioma [Phase 3]
Phase 3 trial comparing hyperfractionated radiotherapy with BCNU to conventional radiotherapy with BCNU in supratentorial malignant glioma.
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CLINICAL_TRIALS trial_result · 2019-10-30Clinical Trial Update: FET-PET for Evaluation of Response of Recurrent GBM to Avastin [Phase 2]
Phase 2 trial evaluating FET-PET to assess response of recurrent glioblastoma to Avastin has completed with results posted in 2019.
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FDA approval · 2019-07-16FDA Approved: TEMOZOLOMIDE — Supplemental Application (Amneal Pharmaceuticals LLC)
The FDA approved Amneal Pharmaceuticals LLC's supplemental application for temozolomide, a generic version of Temodar, under ANDA 203691.
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CLINICAL_TRIALS trial_result · 2019-07-10Clinical Trial Update: Hydroxychloroquine, Radiation, and Temozolomide Treating Patients With Newly Diagnosed Glioblastoma Multiforme [Phase 1, Phase 2]
Phase 1/Phase 2 trial evaluating hydroxychloroquine combined with radiation and temozolomide for newly diagnosed glioblastoma multiforme; st…
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CLINICAL_TRIALS trial_result · 2019-06-12Clinical Trial Update: A Phase 2 Evaluation of TRC105 In Combination With Bevacizumab in Patients With Glioblastoma [Phase 2]
Phase 2 study evaluating TRC105 in combination with bevacizumab in glioblastoma completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-06-12Clinical Trial Update: Neural Progenitor Cell Sparing Radiation Therapy Plus Temozolomide [NA]
A completed clinical trial evaluating neural progenitor cell-sparing radiation therapy in combination with temozolomide for glioblastoma mul…
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CLINICAL_TRIALS trial_result · 2019-05-03Clinical Trial Update: Tumor Lysate Pulsed Dendritic Cell Immunotherapy for Patients With Brain Tumors [Phase 2]
Phase 2 clinical trial update for tumor lysate-pulsed dendritic cell immunotherapy in patients with glioblastoma.
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CLINICAL_TRIALS trial_result · 2019-04-25Clinical Trial Update: Border Zone Stereotactic Radiosurgery With Bevacizumab in Patients With Glioblastoma Multiforme [Phase 2]
Phase 2 trial evaluating border zone stereotactic radiosurgery with bevacizumab in glioblastoma multiforme has completed with results posted…