Glioblastoma Multiforme
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2025-05-07Clinical Trial Update: Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy [Phase 1]
A Phase 1 trial evaluating a combination of temozolomide, memantine hydrochloride, mefloquine, and metformin hydrochloride in glioblastoma m…
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: A Supportive Group Intervention for Caregivers to Patients Diagnosed With a Glioblastoma [NA]
The document describes a planned clinical trial evaluating a supportive group intervention for caregivers of patients with glioblastoma mult…
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: Photodynamic Therapy for Glioblastoma Multiforme Based on Metaverse and Yellow Fluorescence
A clinical trial update for photodynamic therapy targeting glioblastoma multiforme using metaverse-based planning and yellow fluorescence im…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Repeated Super-selective Intraarterial Cerebral Infusion Of Bevacizumab Plus Carboplatin For Treatment Of Relapsed/Refractory GBM And Anaplastic Astrocytoma [Phase 1, Phase 2]
A Phase 1/2 trial of repeated super-selective intraarterial bevacizumab plus carboplatin for relapsed/refractory glioblastoma multiforme and…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM) [Phase 1]
A Phase 1 clinical trial investigating a laparoscopically harvested omental autograft to bypass the blood-brain barrier in recurrent gliobla…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Spatiotemporal Dimensions of Metabolism in Autochthonous Tumors of GBM Patients
Clinical trial update on spatiotemporal metabolism in autochthonous tumors of glioblastoma patients; the study is currently active but not r…
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: ERC1671/GM-CSF/Cyclophosphamide for the Treatment of Glioblastoma Multiforme [Phase 2]
Phase 2 clinical trial update for ERC1671 in combination with GM-CSF and cyclophosphamide for glioblastoma multiforme and gliosarcoma. The s…
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CLINICAL_TRIALS research · 2024-11-29Clinical Trial Update: Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma [Phase 1]
Phase 1 study assessing safety and pharmacokinetics of oral OKN-007 in adults with recurrent high-grade glioma. The trial includes patients …
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CLINICAL_TRIALS trial_result · 2024-11-29Clinical Trial Update: UNIty-Based MR-Linac Guided AdapTive RadiothErapy for High GraDe Glioma: a Phase 2 Trial [NA]
The Phase 2 trial evaluating UNITY-based MR-Linac guided adaptive radiotherapy for glioblastoma multiforme has completed.
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Lonafarnib and Temozolomide in Treating Patients with Glioblastoma Multiforme That is Recurrent or Did Not Respond to Previous Treatment with Temozolomide [Phase 1]
Phase 1 trial update evaluating lonafarnib in combination with temozolomide for recurrent glioblastoma multiforme and related gliomas.
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: JK-1201I Combined with Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma Multiforme (GBM) [Phase 2]
Phase 2 clinical trial evaluating JK-1201I in combination with adjuvant temozolomide for newly diagnosed glioblastoma multiforme; currently …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM) [NA]
This clinical trial update indicates recruitment for a study evaluating omental tissue autograft in patients with recurrent glioblastoma mul…
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FDA approval · 2024-08-23FDA Approved: TEMOZOLOMIDE — Supplemental Application (CivicaScript LLC)
FDA approved CivicaScript LLC's supplemental application for temozolomide, a generic version of the chemotherapy drug Temozolomide (ANDA 207…
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FDA approval · 2024-08-23FDA Approved: TEMOZOLOMIDE — Original Application (Camber Pharmaceuticals, Inc.)
FDA approved Camber Pharmaceuticals' generic temozolomide through an original application for the treatment of malignant gliomas, including …
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CLINICAL_TRIALS withdrawal · 2024-08-09Clinical Trial Update: Treatment of Recurrent GBM With APG-157 Via Expanded Access
Expanded-access trial of APG-157 for recurrent glioblastoma has been discontinued and is no longer available.
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CLINICAL_TRIALS trial_result · 2024-06-06Clinical Trial Update: Berubicin in Adult Patients With Recurrent Glioblastoma Multiforme (WHO Grade IV) [Phase 1, Phase 2]
This clinical trial update reports that Berubicin in adults with recurrent glioblastoma multiforme (WHO Grade IV) in Phase 1/2 was terminate…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: Efficacy, Safety and CNS Exposure of G-202 (Mipsagargin) in Patients With Recurrent or Progressive Glioblastoma [Phase 2]
Phase 2 study evaluating the efficacy, safety and CNS exposure of G-202 (Mipsagargin) in patients with recurrent or progressive glioblastoma…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Lapatinib With Temozolomide and Regional Radiation Therapy for Patients With Newly-Diagnosed Glioblastoma Multiforme [Phase 2]
This Phase 2 trial update reports on combining lapatinib with temozolomide and regional radiation therapy for patients with newly diagnosed …
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: Phase 2a Study of CAN-2409 With Standard Radiation Therapy for Malignant Glioma [Phase 2]
Phase 2a study of CAN-2409 with standard radiation therapy in malignant glioma (including glioblastoma multiforme) has completed; results po…
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CLINICAL_TRIALS trial_result · 2024-03-13Clinical Trial Update: A Study of Poziotinib in Patients With Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Activating Mutations in Advanced Malignancies [Phase 2]
Phase 2 trial of poziotinib in EGFR or HER2 activating mutations across advanced malignancies was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2024-02-05Clinical Trial Update: Study of XL184 (Cabozantinib) in Adults With Glioblastoma Multiforme [Phase 2]
A Phase 2 clinical trial evaluating cabozantinib (XL184) in adults with glioblastoma multiforme has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Repeated Super-Selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Newly Diagnosed GBM [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluated repeated super-selective intraarterial infusion of bevacizumab for newly diagnosed glioblastoma multifo…
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CLINICAL_TRIALS trial_result · 2024-01-02Clinical Trial Update: Glioblastoma Multiforme (GBM) Proton vs. Intensity Modulated Radiotherapy (IMRT) [Phase 2]
Phase 2 clinical trial comparing proton therapy to intensity-modulated radiotherapy for glioblastoma multiforme has completed; results poste…
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CLINICAL_TRIALS trial_result · 2023-11-22Clinical Trial Update: Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma [Phase 2]
Phase 2 trial evaluating a Protein Phosphatase 2A inhibitor in recurrent glioblastoma and related gliomas completed, with results posted in …
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: Low Dose Radiation Therapy for Glioblastoma Multiforme [Phase 2]
Phase 2 trial update on low dose radiation therapy for high-grade glioma (glioblastoma multiforme).