Gastrointestinal Stromal Tumors
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CLINICAL_TRIALS trial_result · 2019-07-19Clinical Trial Update: MITIGATE-NeoBOM: A Study to Evaluate 68Ga- NeoBOMB1 in Patients With Advanced TKI-treated GIST Using PET/CT [Phase 1, Phase 2]
A development-stage clinical trial evaluating 68Ga-NeoBOMB1 in advanced, TKI-treated gastrointestinal stromal tumors using PET/CT has comple…
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CLINICAL_TRIALS trial_result · 2018-03-12Clinical Trial Update: A Study of Sunitinib In Young Patients With Advanced Gastrointestinal Stromal Tumor [Phase 2]
A Phase 2 clinical trial evaluating sunitinib in young patients with advanced gastrointestinal stromal tumors has completed with results pos…
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CLINICAL_TRIALS trial_result · 2017-06-22Clinical Trial Update: Phase II Study Aiming to Evaluate the Efficacy and Safety of Nilotinib Patients With Gastrointestinal Stromal Tumors (GIST) Resistant or Intolerant to Imatinib and or to 2nd Line Tyrosine Kinas (TK) Inhibitor [Phase 2]
This is a completed Phase II trial assessing the efficacy and safety of nilotinib in patients with gastrointestinal stromal tumors that are …
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CLINICAL_TRIALS trial_result · 2017-05-10Clinical Trial Update: Pazopanib in Advanced Gastrointestinal Stromal Tumors Refractory to Imatinib and Sunitinib [Phase 2]
This document provides an update on a Phase 2 trial of pazopanib in advanced gastrointestinal stromal tumors refractory to imatinib and suni…
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CLINICAL_TRIALS trial_result · 2017-04-14Clinical Trial Update: The Oncopanel Pilot (TOP) Study
The Oncopanel Pilot (TOP) Study status is listed as completed in this ClinicalTrials.gov update. The update enumerates several cancer indica…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Efficacy and Safety of AMN107 in Patients With GastroIntestinal Stromal Tumors (GIST) Who Have Failed Both Imatinib and Sunitinib [Phase 2]
This Phase 2 trial evaluates the efficacy and safety of AMN107 (nilotinib) in patients with gastrointestinal stromal tumors who progressed a…
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CLINICAL_TRIALS trial_result · 2016-11-01Clinical Trial Update: Efficacy of Nilotinib in Adult Patients With Gastrointestinal Stromal Tumors Resistant to Imatinib and Sunitinib. [Phase 3]
A Phase 3 trial evaluating nilotinib in adults with gastrointestinal stromal tumors resistant to imatinib and sunitinib has completed and po…
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CLINICAL_TRIALS trial_result · 2016-10-21Clinical Trial Update: Special Investigation For Gist Of Sunitinib Malate (Regulatory Post Marketing Commitment Plan).
Clinical trial update for a post-marketing commitment study of sunitinib malate in gastrointestinal stromal tumors has completed with result…
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CLINICAL_TRIALS trial_result · 2016-04-26Clinical Trial Update: Post Marketing Surveillance Study To Observe Safety And Efficacy Of Sutene
A post-marketing surveillance study evaluating the safety and efficacy of Sutene in patients with gastrointestinal stromal tumors; the study…
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CLINICAL_TRIALS trial_result · 2016-03-17Clinical Trial Update: Detection of CF-DNA in Patients With Gastrointestinal Stromal Tumors (GIST) [Phase 3]
Phase 3 clinical trial assessing the detection of circulating free DNA in patients with Gastrointestinal Stromal Tumors has completed.
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: Open-label Trial of GlivecWith Unresectable or Metastatic Malignant Gastrointestinal Stromal Tumors [Phase 3]
Open-label Phase 3 trial of Glivec (imatinib) for unresectable or metastatic malignant gastrointestinal stromal tumors has completed.
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CLINICAL_TRIALS trial_result · 2015-08-10Clinical Trial Update: Efficacy and Safety of Dovitinib in Patients With Gastrointestinal Stromal Tumors Refractory and/or Intolerant to Imatinib [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of dovitinib in patients with gastrointestinal stromal tumors refractory and/or in…
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CLINICAL_TRIALS trial_result · 2015-07-28Clinical Trial Update: Rechallenge of Imatinib in GIST Having no Effective Treatment: RIGHT [Phase 3]
Phase 3 clinical trial update on rechallenge of Imatinib in gastrointestinal stromal tumors after prior treatment failures; study completed …
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CLINICAL_TRIALS trial_result · 2015-07-27Clinical Trial Update: Adjuvant Imatinib in High-risk Gastrointestinal Stromal Tumor (GIST) With C-kit Mutation [Phase 2]
Phase 2 trial updating adjuvant imatinib in high-risk gastrointestinal stromal tumor (GIST) with C-kit mutation; completed with results post…
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CLINICAL_TRIALS trial_result · 2015-04-10Clinical Trial Update: WB-DWI for Early Prediction of Therapy Response in Patients With Advanced Metastatic GIST Treated With Regorafenib
This clinical trial update describes using whole-body diffusion-weighted imaging to predict early response to regorafenib in patients with a…
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CLINICAL_TRIALS trial_result · 2014-12-15Clinical Trial Update: Regorafenib in Subjects With Gastrointestinal Stromal Tumors (GIST) Who Have Progressed After Standard Therapy
A clinical trial evaluating regorafenib in patients with gastrointestinal stromal tumors that progressed after standard therapy is no longer…
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CLINICAL_TRIALS trial_result · 2014-03-26Clinical Trial Update: Nilotinib 800 Mg And Imatinib 800 Mg For The Treatment Of Patients With Gastrointestinal Stromal Tumors (Gist) Refractory To Imatinib 400 Mg [Phase 3]
A Phase 3 trial evaluating high-dose nilotinib with high-dose imatinib in Gastrointestinal Stromal Tumors refractive to imatinib, which was …
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CLINICAL_TRIALS trial_result · 2014-03-03Clinical Trial Update: Dovitinib for Imatinib/Sumitinib-failed Gastrointestinal Stromal Tumors (GIST): TKI258 [Phase 2]
Phase 2 trial of Dovitinib (TKI258) in imatinib/sunitinib-resistant gastrointestinal stromal tumors has completed with posted results.
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CLINICAL_TRIALS trial_result · 2013-10-25Clinical Trial Update: Study of Regorafenib as a 3rd-line or Beyond Treatment for Gastrointestinal Stromal Tumors (GIST) [Phase 3]
Phase 3 trial updating regorafenib as a third-line or beyond therapy for Gastrointestinal Stromal Tumors (GIST) has completed with results p…
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CLINICAL_TRIALS trial_result · 2013-08-16Clinical Trial Update: Study of Dose Escalation Versus no Dose Escalation of Imatinib in Metastatic Gastrointestinal Stromal Tumors (GIST) Patients [Phase 3]
Phase 3 study comparing dose escalation versus no dose escalation of imatinib in metastatic gastrointestinal stromal tumors was terminated; …
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CLINICAL_TRIALS trial_result · 2012-12-11Clinical Trial Update: Study Evaluating IPI-504 in Patients With Gastrointestinal Stromal Tumors (GIST) Following Failure of at Least Imatinib and Sunitinib [Phase 3]
A Phase 3 study evaluating the Hsp90 inhibitor IPI-504 for gastrointestinal stromal tumors after failure of imatinib and sunitinib has been …
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CLINICAL_TRIALS trial_result · 2012-08-07Clinical Trial Update: Post-Marketing Clinical Study of Postoperative Adjuvant Therapy With Imatinib Mesylate in Patients With Gastrointestinal Stromal Tumors (GIST) [Phase 4]
Post-marketing Phase 4 study update evaluating postoperative adjuvant therapy with imatinib mesylate in patients with gastrointestinal strom…
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CLINICAL_TRIALS trial_result · 2012-05-01Clinical Trial Update: Phase II Clinical Study of Imatinib Mesylate in Patients With Malignant Gastrointestinal Stromal Tumors (Extension Study) [Phase 2]
A completed Phase II extension study evaluating imatinib mesylate in patients with malignant gastrointestinal stromal tumors.
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CLINICAL_TRIALS trial_result · 2012-01-20Clinical Trial Update: Sorafenib for Imatinib/Sunitinib-failed GIST [Phase 2]
A Phase 2 trial evaluating sorafenib in patients with gastrointestinal stromal tumors that progressed after imatinib and sunitinib has compl…
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CLINICAL_TRIALS trial_result · 2011-08-29Clinical Trial Update: Nilotinib in Advanced Gastrointestinal Stromal Tumors (GIST) [Phase 2]
A Phase 2 trial of nilotinib in patients with advanced gastrointestinal stromal tumors was terminated; results were posted in August 2011.