Gastroesophageal Reflux Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: LINX vs Fundoplication [Phase 3]
Phase 3 clinical trial comparing the LINX Reflux Management System to fundoplication for gastroesophageal reflux disease is currently recrui…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: Real-life Study of Changes of Gastroesophageal Reflux Disease Manifestations Due to Behavioural and Diet Adherence [NA]
Real-world clinical trial investigating how adherence to behavioral and dietary changes affects Gastroesophageal Reflux Disease manifestatio…
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FDA approval · 2025-08-01FDA Approved: METOCLOPRAMIDE — Supplemental Application (Ipca Laboratories Limited)
The FDA approved a supplemental application for metoclopramide from Ipca Laboratories Limited, indicating an approved change to the ANDA.
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: The Mechanism Versus PPI Trial [Phase 4]
Phase 4 clinical trial update recruiting to compare a mechanism-based approach against a proton pump inhibitor for laryngopharyngeal reflux …
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Transpyloric Versus Gastric Feeding in Bronchopulmonary Dysplasia [NA]
This clinical trial compares transpyloric feeding to gastric feeding in infants with bronchopulmonary dysplasia; it is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Morphological Markers of Gastroesophageal Reflux Disease (GERD)
A Baylor College of Medicine clinical trial update on morphological markers of gastroesophageal reflux disease; the study is currently activ…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Clinical Trial for the Comparative Evaluation of Acid Suppression and Symptom Management of Gastroesophageal Reflux Disease With the Administration of Tegoprazan or Pantoprazole [Phase 4]
A Phase 4 clinical trial update comparing tegoprazan and pantoprazole for acid suppression and symptom management in gastroesophageal reflux…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Initiation of Acid Suppression Therapy Prospective Outcomes for Laryngomalacia [Phase 1, Phase 2]
A Phase 1/2 trial evaluating acid suppression therapy for laryngomalacia and Gastroesophageal reflux disease was terminated, with results po…
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FDA approval · 2025-07-16FDA Approved: FAMOTIDINE — Original Application (Sagent Pharmaceuticals)
FDA approved the original application for famotidine from Sagent Pharmaceuticals, marking the approval of a generic product.
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: The Effect of the Reflux Band™ Upper Esophageal Sphincter (UES) Assist Device on Reflux for Lung Transplant Recipients [NA]
This clinical trial evaluates whether the Reflux Band Upper Esophageal Sphincter Assist Device reduces gastroesophageal reflux in lung trans…
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FDA approval · 2025-07-09FDA Approved: FAMOTIDINE — Original Application (Aurobindo Pharma Limited)
FDA approved the original abbreviated new drug application (ANDA) for famotidine from Aurobindo Pharma Limited, a generic version of famotid…
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Manual Therapy and Gastroesophageal Reflux Disease in Patients With Hiatal Hernia [NA]
A clinical trial evaluating manual therapy for gastroesophageal reflux disease in patients with hiatal hernia has completed.
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Mandibular Advancement Devices for Reflux in Obstructive Sleep Apnea [Phase 3]
Phase 3 trial evaluating mandibular advancement devices to treat gastroesophageal reflux disease in obstructive sleep apnea; currently not y…
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CLINICAL_TRIALS withdrawal · 2025-06-29Clinical Trial Update: Treatment Use of Domperidone for Gastroparesis
This clinical trial update indicates that the domperidone trial for gastroparesis is no longer available.
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Intestinal Microbiota After PPI Treatment
A clinical trial update examining how proton pump inhibitor treatment affects the intestinal microbiota, with the study currently not yet re…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Evaluation of the Efficacy and Safety of Eolo in Patients With NERD [NA]
This update reports the completed clinical trial evaluating the efficacy and safety of Eolo in patients with non-erosive reflux disease and …
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Development of Machine Learning Models to Predict Postoperative GERD Symptom Resolution After Laparoscopic Nissen Fundoplication
This clinical trial update describes the development of machine learning models to predict postoperative symptom resolution of gastroesophag…
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: PPI Refractory - GERD Mechanisms in Systemic Sclerosis
The trial investigates mechanisms of proton pump inhibitor-refractory gastroesophageal reflux disease in systemic sclerosis and is currently…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Vonaprazan Versus Esomeprazole for Healing of LA Grade B or Higher Esophagitis After POEM [NA]
A clinical trial in India compares vonoprazan versus esomeprazole for healing LA Grade B or higher esophagitis after POEM; the study is curr…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Normal Values of Ambulatory 24-hour Oesophageal pH-impedance Monitoring in an Indian Cohort of Participants
A clinical trial to establish normal reference values for ambulatory 24-hour esophageal pH-impedance monitoring in an Indian population with…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Functional Changes in the Stomach and Esophagus After One Anastomosis Gastric Bypass- OAGB [NA]
This ClinicalTrials.gov entry documents a study evaluating functional changes in the stomach and esophagus after One Anastomosis Gastric Byp…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Biomarkers of Airway Disease, Barrett's and Underdiagnosed Reflux Noninvasively (BADBURN)
Trial registry update for the BADBURN study, a noninvasive biomarker project investigating airway disease, Barrett esophagus, and underdiagn…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: A Post-market Registry to Assess Safety and Performance of RefluxStop™ in the Treatment of GERD in General Hospital Practice [NA]
A post-market registry is planned to assess the safety and performance of RefluxStop for gastroesophageal reflux disease in general hospital…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: A Blinded Randomized Clinical Study of RefluxStop™ Compared With Nissen Fundoplication in the Treatment of GERD [NA]
A blinded randomized clinical trial comparing RefluxStop to Nissen fundoplication for Gastroesophageal Reflux Disease is listed as not yet r…
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FDA approval · 2025-06-02FDA Approved: FAMOTIDINE — Original Application (Lannett Company, Inc.)
FDA approved the original ANDA for famotidine from Lannett Company, Inc., establishing a generic version of famotidine.