Gastroesophageal Reflux Disease
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CLINICAL_TRIALS withdrawal · 2025-10-10Clinical Trial Update: Diagnostic Tests in Supra-Esophageal Gastroesophageal Reflux Disease (SE-GERD) [NA]
A clinical trial evaluating diagnostic tests for supra-esophageal gastroesophageal reflux disease sponsored by the Medical College of Wiscon…
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CLINICAL_TRIALS withdrawal · 2025-06-29Clinical Trial Update: Treatment Use of Domperidone for Gastroparesis
This clinical trial update indicates that the domperidone trial for gastroparesis is no longer available.
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CLINICAL_TRIALS withdrawal · 2025-04-24Clinical Trial Update: Antireflux Ablation Therapy (ARAT) Vs Antireflux Mucosectomy (ARMS) In The Management Of Gastroesophageal Reflux Disease [NA]
A clinical trial evaluating Antireflux Ablation Therapy (ARAT) versus Antireflux Mucosectomy (ARMS) for gastroesophageal reflux disease has …
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CLINICAL_TRIALS withdrawal · 2025-04-01Clinical Trial Update: Study Comparing Esomeprazole Associated With Sodium Bicarbonate From Eurofarma and Esomeprazole in Treatment of Gastroesophageal Reflux Disease ESOBIC [Phase 3]
A Phase 3 trial comparing esomeprazole with sodium bicarbonate versus esomeprazole alone for gastroesophageal reflux disease has been withdr…
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CLINICAL_TRIALS withdrawal · 2024-08-05Clinical Trial Update: Transoral Incisionless Fundoplication (TIF) for Laryngopharyngeal Reflux (LPR) Patients
The clinical trial evaluating Transoral Incisionless Fundoplication (TIF) for laryngopharyngeal reflux and GERD has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-08-01Clinical Trial Update: Domperidone Expanded Access Protocol for Patients With Gastrointestinal Disorders
Clinical trial update indicates that the expanded access protocol for domperidone in gastrointestinal disorders is no longer available.
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CLINICAL_TRIALS withdrawal · 2023-01-05Clinical Trial Update: Cardiac Safety of Lansoprazole and Domperidon Combination [Phase 4]
A Phase 4 trial evaluating the cardiac safety of a lansoprazole and domperidone combination was withdrawn.
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EMA withdrawal · 2022-01-18EMA Withdrawn: Pantoloc Control (pantoprazole) — Takeda GmbH
Pantoloc Control (pantoprazole) has been withdrawn from the European market by Takeda GmbH.
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CLINICAL_TRIALS withdrawal · 2021-10-08Clinical Trial Update: Study of the Effects of Pantoprazole on Levels of Prescribed Psychiatric Medications [Phase 4]
A Phase 4 trial investigating pantoprazole's effects on levels of prescribed psychiatric medications has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-11-17Clinical Trial Update: In Infants With Laryngomalacia, Does Acid-Blocking Medication Improve Respiratory Symptoms? [NA]
Clinical trial investigating acid-blocking medications for respiratory symptoms in infants with laryngomalacia has been withdrawn. The relat…
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CLINICAL_TRIALS withdrawal · 2017-10-16Clinical Trial Update: RELIEF Europe Study [NA]
The RELIEF Europe Study, sponsored by Torax Medical, evaluating GERD and obesity-related conditions, has been terminated.
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CLINICAL_TRIALS withdrawal · 2017-08-29Clinical Trial Update: Placebo Controlled Study of Baclofen for GERD in Children With Cerebral Palsy [Phase 4]
A Phase 4 placebo-controlled trial of baclofen for gastroesophageal reflux disease in children with cerebral palsy has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-04-14Clinical Trial Update: PPI Versus Placebo in Severe Functional Heartburn [NA]
A clinical trial evaluating a proton pump inhibitor versus placebo for severe functional heartburn was withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-04-10Clinical Trial Update: Correlation of High Resolution Esophageal Manometry With Symptoms
A clinical trial investigating the correlation between high-resolution esophageal manometry and patient symptoms has been withdrawn, involvi…
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CLINICAL_TRIALS withdrawal · 2017-03-27Clinical Trial Update: Valvuloplasty as Alternative to Toupet Fundoplication for GERD [NA]
A clinical trial comparing valvuloplasty to Toupet fundoplication for gastroesophageal reflux disease has been withdrawn.
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EMA withdrawal · 2016-11-15EMA Withdrawn: Pantecta Control (pantoprazole) — Takeda GmbH
EMA confirms withdrawal of Pantecta Control (pantoprazole) from the market by Takeda GmbH, related to gastroesophageal reflux treatment.
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CLINICAL_TRIALS withdrawal · 2015-12-09Clinical Trial Update: Confocal Endomicroscopy for Non-Erosive Reflux Disease (CE NERD) [NA]
The clinical trial NCT02039869 evaluating confocal endomicroscopy for nonerosive reflux disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-11-03Clinical Trial Update: Elemental Diets vs. Semi-solid Diets on Gastric Excretion and Gastroesophageal Regurgitation [NA]
A clinical trial comparing elemental and semi-solid diets for gastric excretion and gastroesophageal reflux has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-07-24Clinical Trial Update: Clinical Study, Multicenter, Randomized With 2 Arms of Pantoprazole + Domperidone and Pantoprazole Isolated at the Gastroesophageal Reflux Disease [Phase 3]
A Phase 3 multicenter randomized trial evaluating pantoprazole with and without domperidone for gastroesophageal reflux disease has been wit…
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CLINICAL_TRIALS withdrawal · 2015-06-19Clinical Trial Update: Nasopharyngeal 24 Hour pH Monitoring in Health Adult Volunteers [NA]
The clinical trial investigating nasopharyngeal 24-hour pH monitoring in healthy adult volunteers for gastroesophageal reflux disease has be…
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CLINICAL_TRIALS withdrawal · 2015-04-29Clinical Trial Update: Evaluation of the Safety and Effectiveness of Tailored Transoral Incisionless Fundoplication (TIF) Using EsophyX for the Treatment of GERD [Phase 2]
Phase 2 trial evaluating Tailored Transoral Incisionless Fundoplication (TIF) using the EsophyX device for gastroesophageal reflux disease h…
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CLINICAL_TRIALS withdrawal · 2013-01-16Clinical Trial Update: Impact of Maternal-infant Therapeutics on Safety, Mortality, and Disability
A Duke University-sponsored clinical trial evaluating maternal-infant therapeutics for safety, mortality, and disability has been withdrawn;…
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CLINICAL_TRIALS withdrawal · 2012-12-20Clinical Trial Update: Tongue Exercises and Reflux Therapy for Upper Airway Resistance Syndrome [Phase 1]
A Phase 1 clinical trial evaluating tongue exercises and reflux therapy for upper airway resistance syndrome has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2012-10-26Clinical Trial Update: A Study to Evaluate the Role of Alternative Medicine in Difficult to Treat GERD Patients [NA]
A clinical trial evaluating the role of alternative medicine in difficult-to-treat gastroesophageal reflux disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2012-10-11Clinical Trial Update: Randomized Trial for Pharmacogenomics-based Proton Pump Inhibitor Therapy in Children [Phase 4]
A Phase 4 randomized trial evaluating pharmacogenomics-based proton pump inhibitor therapy in children for gastroesophageal reflux disease h…