Gastroesophageal Reflux Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2010-11-19Clinical Trial Update: Esomeprazole for Treatment of GERD in Pediatric Patients [Phase 4]
Phase 4 trial update on esomeprazole for treating gastroesophageal reflux disease and associated esophagitis in pediatric patients has compl…
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CLINICAL_TRIALS trial_result · 2010-10-29Clinical Trial Update: Conventional Nissen Fundoplication Versus Laparoscopic Nissen Fundoplication [NA]
A completed clinical trial comparing conventional open Nissen fundoplication to laparoscopic Nissen fundoplication for Gastroesophageal refl…
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CLINICAL_TRIALS trial_result · 2010-10-21Clinical Trial Update: Diagnosis and Response to Treatment Using a Reliable Gastroesophageal Reflux Disease (GERD) Questionnaire: An In Clinical Practice Study
A completed clinical study evaluating a GERD questionnaire for diagnosing and monitoring response to treatment in gastroesophageal reflux di…
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CLINICAL_TRIALS trial_result · 2010-10-19Clinical Trial Update: Waist Circumference Versus Body Mass Index to Predict Severity of Gastroesophageal Reflux Disease
A completed clinical trial evaluated whether waist circumference or body mass index better predicts the severity of gastroesophageal reflux …
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CLINICAL_TRIALS trial_result · 2010-10-19Clinical Trial Update: Endoscopic Findings in Patients With Typical Gastroesophageal Reflux Disease (GERD) Symptoms
The update summarizes endoscopic findings from a completed clinical trial in patients with typical gastroesophageal reflux disease symptoms.
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CLINICAL_TRIALS trial_result · 2010-10-05Clinical Trial Update: Pharmacokinetic and Safety of Dexlansoprazole in Adolescents With Gastroesophageal Reflux Disease [Phase 1]
Phase 1 study assessing the pharmacokinetics and safety of dexlansoprazole in adolescents with gastroesophageal reflux disease.
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CLINICAL_TRIALS trial_result · 2010-09-24Clinical Trial Update: Comparison of Antisecretory Effect of a Single Dose of Rabeprazole 20 mg and Omeprazole 20 mg in Obese Subjects [Phase 2]
This Phase 2 trial compared the antisecretory effect of a single 20 mg dose of rabeprazole versus 20 mg omeprazole in obese adults with gast…
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CLINICAL_TRIALS trial_result · 2010-09-24Clinical Trial Update: Efficacy of Pantoprazole in Patients Older Than 12 Years With Reflux Associated Sleep Disorders (PULS)
A completed clinical trial (PULS) assessed the efficacy of pantoprazole in patients older than 12 with reflux-associated sleep disorders, in…
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CLINICAL_TRIALS trial_result · 2010-09-24Clinical Trial Update: Efficacy of Pantoprazole 20/40 mg Once Daily (od) in Patients Older Than 12 Years Who Have Gastrointestinal Symptoms of Reflux Disease
This clinical trial update reports the efficacy of pantoprazole 20/40 mg once daily in patients aged 12 years and older with gastroesophagea…
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CLINICAL_TRIALS trial_result · 2010-09-22Clinical Trial Update: Investigation of the Association Between Nasal Polyposis and Extraesophageal Reflux Disease [NA]
Completed clinical trial evaluating the association between nasal polyps and extraesophageal reflux disease; results were posted in 2010.
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CLINICAL_TRIALS trial_result · 2010-09-16Clinical Trial Update: Efficacy of Pantoprazole in Patients Older Than 12 Years Who Have Symptoms of Non-Erosive Reflux Disease (NERD) or Erosive Gastroesophageal Reflux Disease (eGERD)
Completed clinical trial assessing the efficacy of pantoprazole in patients over 12 with non-erosive reflux disease or erosive GERD.
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CLINICAL_TRIALS trial_result · 2010-09-15Clinical Trial Update: Pantoprazole 20/40 mg in the Treatment of Symptomatic Reflux Disease With Focus on Sleep Disorders
This clinical trial update summarizes a completed study of pantoprazole 20/40 mg for symptomatic reflux disease, with a focus on sleep disor…
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CLINICAL_TRIALS trial_result · 2010-09-01Clinical Trial Update: A Study to Assess the Efficacy, Safety and Tolerability of Tegaserod Alone and in Combination With Omeprazole Given Orally in Patients With Symptoms of Symptomatic Gastroesophageal Reflux Disease (sGERD) [Phase 2]
A Phase 2 study assessing tegaserod alone and in combination with omeprazole for symptomatic gastroesophageal reflux disease has completed.
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CLINICAL_TRIALS trial_result · 2010-08-30Clinical Trial Update: A Study to Compare the Number of Patients With Gastro-Oesophageal Reflux Disease (GORD) Achieving Heartburn and Regurgitation Symptom Resolution After Treatment With Either Rabeprazole Sodium 20mg, Esomeprazole 20mg or Esomeprazole 40mg [Phase 4]
Phase 4 trial comparing three proton-pump inhibitor regimens (rabeprazole 20 mg, esomeprazole 20 mg, and esomeprazole 40 mg) in gastroesopha…
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CLINICAL_TRIALS trial_result · 2010-08-23Clinical Trial Update: Proton Pump Inhibitor (PPI) Therapy for Newly Diagnosed Esophagitis
A completed clinical trial update evaluates proton pump inhibitor therapy for patients newly diagnosed with esophagitis, including erosive e…
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CLINICAL_TRIALS trial_result · 2010-08-19Clinical Trial Update: Role of Pain Modulation in GERD Patients Who Failed Standard Dose Proton Pump Inhibitors (PPI) [Phase 4]
This Phase 4 trial update reports the completion of a study evaluating pain modulation strategies in patients with gastroesophageal reflux d…
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CLINICAL_TRIALS trial_result · 2010-08-19Clinical Trial Update: Effect of Pantoprazole 40mg Daily vs Placebo on Power Spectral Analysis of the Sleep EEG of Patients With GERD. [Phase 2, Phase 3]
This document reports a completed Phase 2/3 trial evaluating pantoprazole 40 mg daily vs placebo in GERD, with outcomes based on power spect…
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CLINICAL_TRIALS trial_result · 2010-08-19Clinical Trial Update: To Determine if Sleep Deprivation Results in Increased Esophageal Acid Exposure
A completed clinical trial evaluated whether sleep deprivation increases esophageal acid exposure in gastroesophageal reflux disease.
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CLINICAL_TRIALS trial_result · 2010-07-22Clinical Trial Update: The Use of Lansoprazole to Treat Infants With Symptoms of Gastroesophageal Reflux [Phase 3]
Phase 3 trial evaluating lansoprazole for infants with gastroesophageal reflux symptoms has completed; sponsor Takeda.
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CLINICAL_TRIALS trial_result · 2010-07-22Clinical Trial Update: A Study to Evaluate the Effect of Lansoprazole on Hospitalized Neonates With Gastroesophageal Reflux Disease [Phase 1]
Phase 1 study evaluating lansoprazole in hospitalized neonates with gastroesophageal reflux disease has completed.
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CLINICAL_TRIALS trial_result · 2010-07-22Clinical Trial Update: A Study to Evaluate the Effect of Lansoprazole on Infants With Gastroesophageal Reflux Disease. [Phase 1]
A Phase 1 clinical trial evaluating the effects of lansoprazole in infants with gastroesophageal reflux disease has completed.
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CLINICAL_TRIALS trial_result · 2010-07-21Clinical Trial Update: Intravenous vs Oral Lansoprazole on Gastric Acid Secretion in Subjects With Erosive Esophagitis [Phase 2]
Phase 2 trial comparing intravenous versus oral lansoprazole in patients with erosive esophagitis and gastroesophageal reflux disease to eva…
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CLINICAL_TRIALS trial_result · 2010-07-13Clinical Trial Update: Effect of Coffee on Gastro-Esophageal Disease in Patients With Symptoms of Reflux [NA]
A completed clinical trial investigated the effect of coffee on gastroesophageal reflux disease symptoms in patients with reflux.
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CLINICAL_TRIALS trial_result · 2010-07-12Clinical Trial Update: Prevalence of Gastroesophageal Reflux Disease in Primary Care Patients With Upper Gastrointestinal Symptoms
This clinical trial update reports the prevalence of gastroesophageal reflux disease among primary care patients with upper gastrointestinal…
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CLINICAL_TRIALS trial_result · 2010-07-07Clinical Trial Update: A Study of the Use of High-dose Proton Pump Inhibitor for the Treatment of Gastro-oesophageal Reflux Related Non-cardiac Chest Pain - a Randomized Double-blind Placebo-controlled Study [NA]
This document reports on a randomized, double-blind, placebo-controlled trial evaluating the use of high-dose proton pump inhibitors for gas…