Gastroesophageal Reflux Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2011-02-24Clinical Trial Update: Survey Examining the Frequency and Severity of Acid Related Symptoms While Taking Nexium
A completed clinical trial update that examined how often and how severely patients taking Nexium (esomeprazole) experience acid-related sym…
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CLINICAL_TRIALS trial_result · 2011-02-07Clinical Trial Update: Partial Response to PPI Treatment: The Cost to Society and the Burden to the Patient - a Study in France
A completed clinical trial in France evaluating the societal costs and patient burden associated with partial response to proton pump inhibi…
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CLINICAL_TRIALS trial_result · 2011-01-31Clinical Trial Update: A Study to Investigate Use Patterns and Safety in Simulated Actual Over-the-counter (OTC) Use of Rabeprazole Sodium for the Treatment of Heartburn Symptoms
A completed study evaluated use patterns and safety of rabeprazole sodium in simulated over-the-counter use for heartburn symptoms.
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CLINICAL_TRIALS trial_result · 2011-01-25Clinical Trial Update: Open, Randomized, Two Way Crossover 40mg, Orally and Intravenously [Phase 4]
A Phase 4 open, randomized two-way crossover trial in gastroesophageal reflux disease evaluating 40 mg doses given orally and intravenously;…
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CLINICAL_TRIALS trial_result · 2011-01-25Clinical Trial Update: An Open, Randomized, Two Way Crossover Study Comparing the Effect of 20mg Esomeprazole Administered Orally and Intravenously as a 15 Minute Infusion on Basal and Pentagastrin-Stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD) [Phase 4]
Phase 4 study comparing 20 mg esomeprazole given orally versus intravenously (15-minute infusion) and their effects on basal and pentagastri…
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CLINICAL_TRIALS trial_result · 2011-01-24Clinical Trial Update: Esomeprazole for Relief of Upper Gastrointestinal Symptoms Associated With Continuous Use of NSAIDs [Phase 3]
A Phase 3 trial evaluating esomeprazole for relief of NSAID-associated upper gastrointestinal symptoms in GERD patients has completed.
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CLINICAL_TRIALS trial_result · 2011-01-24Clinical Trial Update: Chest Pain Pilot Study [Phase 3]
Phase 3 chest pain and gastroesophageal reflux disease trial has completed.
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CLINICAL_TRIALS trial_result · 2011-01-24Clinical Trial Update: Sopran - Omeprazole Treatment Versus Surgery [Phase 3]
Phase 3 trial comparing omeprazole treatment with surgery for gastroesophageal reflux disease has completed.
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CLINICAL_TRIALS trial_result · 2011-01-24Clinical Trial Update: Open, Randomized, Two Way Crossover Study Comparing the Effect of Esomeprazole Adminstered Orally and iv [Phase 4]
Phase 4 open-label, randomized two-way crossover trial comparing oral and intravenous esomeprazole for Gastroesophageal reflux disease has b…
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CLINICAL_TRIALS trial_result · 2011-01-24Clinical Trial Update: A Study of Cisapride in Patients With Symptomatic Gastro-Oesophageal Reflux Disease [Phase 4]
A Phase 4 study of cisapride in patients with gastroesophageal reflux disease has been terminated.
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CLINICAL_TRIALS trial_result · 2011-01-24Clinical Trial Update: Study Comparing the Effects of Esomeprazole Adminstered Orally and Intravenously on Basal and Pentrigastrin-stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD) [Phase 4]
Phase 4 clinical trial comparing oral and intravenous esomeprazole on basal and pentagastrin-stimulated acid output in subjects with gastroe…
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CLINICAL_TRIALS trial_result · 2011-01-24Clinical Trial Update: Symptom Adapted Therapy in GERD Patients [Phase 4]
This entry reports a completed Phase 4 clinical trial on symptom-adapted therapy for gastroesophageal reflux disease.
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CLINICAL_TRIALS trial_result · 2011-01-21Clinical Trial Update: Esomeprazole for Prevention of Upper Gastrointestinal Symptoms Associated With Continuous Use of NSAIDs [Phase 3]
This update notes the completion of a Phase 3 trial evaluating esomeprazole to prevent upper gastrointestinal symptoms in patients continuou…
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CLINICAL_TRIALS trial_result · 2011-01-21Clinical Trial Update: Study Comparing Esomeprazole Magnesium 40mg Once Daily Versus Lansoprazole 30 mg Twice Daily in Symptom Control of Subjects With Persistent Gastrooesophageal Reflux Disease (GERD) [Phase 4]
Phase 4 clinical trial comparing esomeprazole magnesium 40 mg daily with lansoprazole 30 mg twice daily for symptom control in persistent ga…
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CLINICAL_TRIALS trial_result · 2011-01-11Clinical Trial Update: Non-interventional Study to Evaluate the Change in Symptoms Scores and Treatment Response After 4 Weeks of Proton-Pump Inhibitors (PPI) Treatment
A non-interventional study completed to evaluate changes in symptom scores and treatment response after 4 weeks of proton-pump inhibitor the…
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CLINICAL_TRIALS trial_result · 2011-01-10Clinical Trial Update: A Pharmacokinetic and Safety Study of Single and Multiple Doses of Rabreprazole in Pediatric Patients With Gastroesophageal Reflux Disease (GERD) 1 to 11 Years Old, Inclusive [Phase 1]
A Phase 1 pharmacokinetic and safety study evaluated single and multiple doses of rabreprazole in children aged 1 to 11 with gastroesophagea…
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CLINICAL_TRIALS trial_result · 2010-12-07Clinical Trial Update: 14473 - D9126C00001 Proof of Principle Study - Effect of AZD2066 on Transient Lower Esophageal Sphincter Relaxations [Phase 1, Phase 2]
This is a completed Phase 1/2 proof-of-principle trial evaluating AZD2066 for reducing transient lower esophageal sphincter relaxations in p…
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CLINICAL_TRIALS trial_result · 2010-12-07Clinical Trial Update: AZD3355 Dose-escalation Study in Healthy Males [Phase 1]
Phase 1 dose-escalation trial of AZD3355 in healthy male volunteers completed, evaluating safety, tolerability, and pharmacokinetics in the …
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CLINICAL_TRIALS trial_result · 2010-12-07Clinical Trial Update: Structured Treatment of Gastroesophageal Reflux in a Company Health Care Setting, -Effect on Quality of Life, Symptoms and Productivity
This completed AstraZeneca-sponsored trial evaluated a structured treatment approach for gastroesophageal reflux disease in a corporate heal…
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CLINICAL_TRIALS trial_result · 2010-12-07Clinical Trial Update: Prevalence of EED and Quality of Life Evaluated by Gastroesophageal Reflux Disease (GERD)-Q in Korean GERD Patients
A completed AstraZeneca-sponsored clinical trial in Korean patients with gastroesophageal reflux disease evaluating the prevalence of erosiv…
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CLINICAL_TRIALS trial_result · 2010-12-07Clinical Trial Update: Gastroesophageal Reflux Disease (GERD) Segmentation: Document How Swiss General Practitioners (GPs) Allocate Their GERD Patients to the Three GERD Patient Segments
A completed AstraZeneca clinical trial examining how Swiss general practitioners segment GERD patients into three distinct groups.
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CLINICAL_TRIALS trial_result · 2010-12-03Clinical Trial Update: Drug Interaction Study Between AZD3355 and Nexium [Phase 1]
The Phase 1 drug interaction study of AZD3355 with Nexium in gastroesophageal reflux disease has completed.
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CLINICAL_TRIALS trial_result · 2010-12-03Clinical Trial Update: Study to Compare Different Formulations of AZD3355 [Phase 1]
An update on a Phase 1 study comparing different formulations of AZD3355 for gastroesophageal reflux disease. The trial has completed.
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CLINICAL_TRIALS trial_result · 2010-11-30Clinical Trial Update: A Study of Efficacy and Safety of "On-demand" Maintenance Therapy With Rabeprazole in Patients With Non-erosive Reflux Disease (NERD) [Phase 3]
A Phase 3 study evaluating the efficacy and safety of on-demand rabeprazole maintenance therapy for non-erosive reflux disease has completed…
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CLINICAL_TRIALS trial_result · 2010-11-19Clinical Trial Update: Safety of Daily Dose Esomeprazole for GERD for Pediatric and Adolescent Patients [Phase 3]
Phase 3 clinical trial update reporting safety data for daily esomeprazole in pediatric and adolescent patients with gastroesophageal reflux…