Gastroesophageal Reflux Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-11-15Clinical Trial Update: A Randomized Controlled Trial of Laparoscopic Nissen Fundoplication Treatment of Patients With Chronic GERD [NA]
This document reports on a completed randomized controlled trial evaluating laparoscopic Nissen fundoplication for chronic gastroesophageal …
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CLINICAL_TRIALS trial_result · 2012-11-09Clinical Trial Update: Esophageal Hypersensitivity Study in Patients With Gastroesophageal Reflux Disease (GERD) [Phase 2]
A Phase 2 study evaluating esophageal hypersensitivity in patients with gastroesophageal reflux disease (GERD) completed, with results poste…
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CLINICAL_TRIALS trial_result · 2012-10-31Clinical Trial Update: To Assess the Efficacy of Esomeprazole 40 mg Once Daily in Subjects Who Still Had Heartburn After Receiving Rabeprazole [Phase 4]
This Phase 4 trial assesses whether once-daily esomeprazole 40 mg improves heartburn in patients who continued to have heartburn after rabep…
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CLINICAL_TRIALS trial_result · 2012-10-29Clinical Trial Update: Novel Imaging Techniques in Barrett's Esophagus [NA]
A completed clinical trial evaluating novel imaging techniques in Barrett's esophagus and gastroesophageal reflux disease.
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CLINICAL_TRIALS trial_result · 2012-10-19Clinical Trial Update: A Three-Period Study to Investigate the Relative Bioavailability and Pharmacodynamic Profiles of a Zegerid 20mg Capsule, Zegerid 20mg Powder for Oral Suspension and Losec 20mg Capsule in Healthy Adult Volunteers Under Fasting Conditions [Phase 1]
This Phase 1 study compares the relative bioavailability and pharmacodynamic profiles of Zegerid 20 mg capsule, Zegerid 20 mg powder for ora…
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CLINICAL_TRIALS trial_result · 2012-10-11Clinical Trial Update: A Study of the Safety and Effectiveness of Rabeprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Pediatric Patients [Phase 3]
A Phase 3 clinical trial assessing the safety and effectiveness of rabeprazole for treating gastroesophageal reflux disease in pediatric pat…
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CLINICAL_TRIALS trial_result · 2012-10-11Clinical Trial Update: Optimal Dosing of Omeprazole in Neonates [Phase 2]
A Phase 2 trial evaluating the optimal dosing of omeprazole in neonates with gastroesophageal reflux disease has completed.
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CLINICAL_TRIALS trial_result · 2012-10-10Clinical Trial Update: A Study of Nexium (Esomeprazole) 40 mg Once Daily in Subjects With Symptoms of Gastroesophageal Reflux Disease (GORD) After Treatment With a Full Dose of Proton Pump Inhibitor (PPI) [Phase 4]
This Phase 4 study evaluated esomeprazole 40 mg once daily for GERD symptoms in patients who had prior full-dose proton pump inhibitor thera…
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CLINICAL_TRIALS trial_result · 2012-09-20Clinical Trial Update: Do Acid Sensing Ion Channels Contribute to Heartburn? [Phase 1]
A Phase 1 trial completed to investigate whether acid-sensing ion channels contribute to heartburn in patients with gastroesophageal reflux …
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CLINICAL_TRIALS trial_result · 2012-09-03Clinical Trial Update: Safety and Efficacy of Lansoprazole in Patients With Reflux Disease [Phase 4]
Phase 4 clinical trial update evaluating the safety and efficacy of Lansoprazole for gastroesophageal reflux disease; results posted after c…
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CLINICAL_TRIALS trial_result · 2012-08-17Clinical Trial Update: Safety and Efficacy of Lansoprazole 30mg Twice Daily in Treatment of Laryngitis Associated With Gastroesophageal Reflux [Phase 4]
Phase 4 trial evaluating the safety and efficacy of lansoprazole 30 mg twice daily for laryngitis associated with gastroesophageal reflux. T…
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CLINICAL_TRIALS trial_result · 2012-08-15Clinical Trial Update: Do Patients Who Have Had Surgery for Achalasia Suffer From Reflux [NA]
A completed clinical trial update examines whether patients who have undergone surgery for achalasia experience reflux.
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CLINICAL_TRIALS trial_result · 2012-08-13Clinical Trial Update: Study to Investigate the Pharmacodynamic Effect of a Single Dose of AZD2516 in Healthy Male Subjects [Phase 2]
This completed Phase 2 pharmacodynamic study evaluated a single dose of AZD2516 in healthy male subjects, with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-08-08Clinical Trial Update: Esomeprazole (NEXIUM) vs. Surgery [Phase 3]
Phase 3 trial comparing esomeprazole (Nexium) with surgery for gastroesophageal reflux disease completed, with results posted.
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CLINICAL_TRIALS trial_result · 2012-07-30Clinical Trial Update: Active Control, Double-blind, Double-dummy, Parallel-group, Randomized Study to Assess the Effect of VECAM 40/300, Administered at Bedtime, vs. Esomeprazole 20 mg, Administered 30-60 Min. Before Dinner, on Daytime and Nighttime GERD Symptoms [Phase 2]
A Phase 2 randomized trial comparing VECAM 40/300 given at bedtime to esomeprazole 20 mg given before dinner, assessing daytime and nighttim…
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CLINICAL_TRIALS trial_result · 2012-07-24Clinical Trial Update: COPD Patients Diagnosed With GERD,COPD Exacerbations After Treatment With High Dose PPI [NA]
This terminated study investigated high-dose proton pump inhibitors in COPD patients with gastroesophageal reflux disease and reported COPD …
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CLINICAL_TRIALS trial_result · 2012-07-17Clinical Trial Update: Effect of Nortriptyline in Cortical Representation of Heartburn in Nonerosive Reflux Disease (NERD) Patients [Phase 3]
A Phase 3 clinical trial evaluating nortriptyline's effect on the cortical representation of heartburn in nonerosive reflux disease has comp…
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CLINICAL_TRIALS trial_result · 2012-07-16Clinical Trial Update: ADX10059 as an add-on Therapy to Proton Pump Inhibitors (PPIs) in Patients With Gastroesophageal Reflux (GERD) [Phase 2]
Phase 2 trial evaluating ADX10059 as an add-on therapy to proton pump inhibitors for gastroesophageal reflux disease has completed.
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CLINICAL_TRIALS trial_result · 2012-07-06Clinical Trial Update: Prevalence of Gastroesophageal Reflux Disease in Peritoneal Dialysis and Hemodialysis Patients
This clinical trial update reports on the prevalence of gastroesophageal reflux disease among patients on peritoneal dialysis and hemodialys…
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CLINICAL_TRIALS trial_result · 2012-06-26Clinical Trial Update: Pantoprazole Magnesium 40 mg Versus Esomeprazole 40 mg in Patients With Erosive Gastroesophageal Reflux Disease [Phase 3]
A Phase 3 trial comparing pantoprazole magnesium 40 mg to esomeprazole 40 mg in patients with erosive gastroesophageal reflux disease has co…
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CLINICAL_TRIALS trial_result · 2012-06-04Clinical Trial Update: Open-label Comparison of 24hr Gastric pH on Days 1, 2, 7 With Once-daily Administration of Lavoltidine 40 mg. [Phase 1]
Open-label Phase 1 study evaluating 24-hour gastric pH on days 1, 2, and 7 after once-daily Lavoltidine 40 mg.
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CLINICAL_TRIALS trial_result · 2012-05-25Clinical Trial Update: Follow-up of Patients Operated Upon for Type II-IV Hiatal Hernia
Follow-up results from patients operated for Type II-IV hiatal hernia; the study conducted by University of Bologna is completed.
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CLINICAL_TRIALS trial_result · 2012-05-10Clinical Trial Update: Symptom Control and Impact on Daily Life in Patients With Gastroesophageal Reflux Disease
This completed AstraZeneca-sponsored clinical trial assessed symptom control and the impact on daily life in patients with gastroesophageal …
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CLINICAL_TRIALS trial_result · 2012-05-07Clinical Trial Update: Effect of Pantoprazole on the Symptoms of Acid Reflux Disease in Adult Patients (BY1023/M3-341) [Phase 3]
Phase 3 trial BY1023/M3-341 evaluated pantoprazole for treating symptoms of acid reflux disease in adults; the study has completed.
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CLINICAL_TRIALS trial_result · 2012-05-07Clinical Trial Update: Symptom Assessment in Adult Patients With Erosive GERD (Gastroesophageal Reflux Disease) or enGERD (Endoscopic-negative GERD) After Treatment With Pantoprazole (BY1023/M3-343) [Phase 3]
Phase 3 clinical trial assessing symptom outcomes in adults with erosive GERD or endoscopic-negative GERD after pantoprazole treatment; the …