Gastroesophageal Reflux Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-05-30Clinical Trial Update: Prospective, Comparative, Randomized, Controlled Trial on the Efficacy of the Treatment of Gastroesophageal Reflux Infant With Magnesium Alginate [NA]
A prospective, randomized trial evaluates the efficacy of magnesium alginate for treating gastroesophageal reflux in infants; current status…
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CLINICAL_TRIALS trial_result · 2013-05-22Clinical Trial Update: Safety and Efficacy of Rabeprazole in Infants With Gastroesophageal Erosive Reflux Disease (GERD) [Phase 3]
A Phase 3 trial evaluated the safety and efficacy of rabeprazole in infants with gastroesophageal reflux disease. The study is completed and…
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CLINICAL_TRIALS trial_result · 2013-05-22Clinical Trial Update: Comparison of Two Omeprazole-Containing Products for Relief of Frequent Heartburn (MK-0764A-036) [Phase 4]
Phase 4 trial comparing two omeprazole-containing products for relief of frequent heartburn; results have been posted.
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CLINICAL_TRIALS trial_result · 2013-05-21Clinical Trial Update: Confocal Laser Microscopy in Non Erosive Reflux Disease
This completed clinical trial evaluates confocal laser endomicroscopy as a diagnostic approach in non-erosive gastroesophageal reflux diseas…
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CLINICAL_TRIALS trial_result · 2013-05-06Clinical Trial Update: Epidemiology of Barrett's Esophagus: A Population Based Study
A Mayo Clinic–sponsored population-based study completed to characterize the epidemiology of Barrett's esophagus and its relation to GERD in…
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CLINICAL_TRIALS trial_result · 2013-04-29Clinical Trial Update: A Pharmacokinetics, Pharmacodynamics and Safety Study of Rabeprazole in New Born Infants With Gastroesophageal Reflux Disease (GERD) [Phase 1]
Phase 1 pharmacokinetic, pharmacodynamic, and safety study of rabeprazole in newborn infants with gastroesophageal reflux disease has comple…
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CLINICAL_TRIALS trial_result · 2013-04-02Clinical Trial Update: Randomized, Double Blind, Placebo Control Trial to Evaluate the Efficacy of Wu-Chu-Yu Tang on Gastroesophageal Reflux Disease (GERD) [Phase 4]
A Phase 4 randomized, double-blind, placebo-controlled trial is evaluating Wu-Chu-Yu Tang for gastroesophageal reflux disease; current statu…
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CLINICAL_TRIALS trial_result · 2013-03-18Clinical Trial Update: Symptom Improvements in Gastroesophageal Reflux Disease (GERD) Patients [Phase 2]
Phase 2 clinical trial update from AstraZeneca reports symptom improvements in patients with gastroesophageal reflux disease; results posted…
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CLINICAL_TRIALS trial_result · 2013-03-11Clinical Trial Update: Safety and Efficacy of IQP-LH-101 in Postprandial Heartburn [Phase 4]
Phase 4 clinical trial evaluating the safety and efficacy of IQP-LH-101 for postprandial heartburn has been completed.
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CLINICAL_TRIALS trial_result · 2013-03-06Clinical Trial Update: Salivary Epidermal Growth Factor (EGF) Concentration Before and After Treatment of Reflux Laryngitis
A completed clinical trial measured salivary epidermal growth factor (EGF) levels before and after treatment of reflux laryngitis in patient…
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CLINICAL_TRIALS trial_result · 2013-02-27Clinical Trial Update: The Frequency of Eosinophilic Esophagitis in Patients With Heartburn That is Refractory to Proton Pump Inhibitors [Phase 4]
Phase 4 trial evaluating how often eosinophilic esophagitis occurs in patients with heartburn refractory to proton pump inhibitors; the stud…
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CLINICAL_TRIALS trial_result · 2013-02-25Clinical Trial Update: Predictors of Proton Pump Inhibitor Response in Gastroesophageal Reflux Disease Patients
This completed clinical trial identifies factors that predict response to proton pump inhibitors in patients with gastroesophageal reflux di…
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CLINICAL_TRIALS trial_result · 2013-02-18Clinical Trial Update: To Assess the Efficacy of Esomeprazole 20mg Once Daily in Subjects Who Still Had Heartburn After Receiving Rabeprazole [Phase 4]
Phase 4 trial evaluating esomeprazole 20 mg once daily in patients with gastroesophageal reflux disease who continued heartburn after rabepr…
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CLINICAL_TRIALS trial_result · 2013-02-08Clinical Trial Update: Study Comparing a Pantoprazole Formulation to the Currently Marketed Tablet for GERD and Erosive Esophagitis [Phase 3]
Phase 3 trial comparing a pantoprazole formulation to the currently marketed pantoprazole tablet in patients with gastroesophageal reflux di…
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CLINICAL_TRIALS trial_result · 2013-01-28Clinical Trial Update: The Use of International GerdQ Questionnaire
A completed clinical trial sponsored by AstraZeneca evaluated the use of the International GerdQ questionnaire in relation to gastroesophage…
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CLINICAL_TRIALS trial_result · 2013-01-21Clinical Trial Update: Does Omeprazole Decrease Intestinal Calcium Absorption? [Phase 4]
A Phase 4 clinical trial investigated whether omeprazole reduces intestinal calcium absorption in individuals with osteoporosis and related …
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CLINICAL_TRIALS trial_result · 2013-01-17Clinical Trial Update: Acid Reflux and Stromal Fibroblasts in Barrett's Esophagus [Phase 1]
Phase 1 trial examining the role of acid reflux and stromal fibroblasts in Barrett's Esophagus has completed.
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CLINICAL_TRIALS trial_result · 2013-01-09Clinical Trial Update: Twenty-Four Hour Combined Multi-Channel Impedance and pH Ambulatory Monitoring: Impedance Reflux Episodes of Patients On and Off Proton Pump Inhibitor Therapy [NA]
This completed clinical trial evaluated impedance-pH monitoring in GERD patients on and off proton pump inhibitor therapy, with results post…
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CLINICAL_TRIALS trial_result · 2013-01-04Clinical Trial Update: A Dose-finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients With Erosive Esophagitis. [Phase 2]
A Phase 2b dose-finding trial of AZD0865 with esomeprazole in gastroesophageal reflux disease with erosive esophagitis has completed.
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CLINICAL_TRIALS trial_result · 2013-01-04Clinical Trial Update: A Dose-finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients Without Erosive Esophagitis. [Phase 2]
A completed Phase IIb dose-finding trial evaluated AZD0865 in combination with esomeprazole for gastroesophageal reflux disease without eros…
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CLINICAL_TRIALS trial_result · 2012-12-28Clinical Trial Update: Detection of Minimal Change Esophagitis Using Confocal Laser Endomicroscopy
This clinical trial update notes the termination of a study evaluating detection of minimal change esophagitis in gastroesophageal reflux di…
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CLINICAL_TRIALS trial_result · 2012-12-11Clinical Trial Update: Nexium (Esomeprazole) in Symptom Adapted Therapy in GERD Patients [Phase 4]
Phase 4 trial evaluating symptom-adapted therapy with Nexium (esomeprazole) in gastroesophageal reflux disease; results have been posted.
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CLINICAL_TRIALS trial_result · 2012-12-10Clinical Trial Update: A Study to Monitor Intragastric pH in Patients Taking Rabeprazole vs. Patients Taking Pantoprazole [Phase 1]
A Phase 1 study comparing intragastric pH in GERD patients treated with rabeprazole versus pantoprazole has completed.
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CLINICAL_TRIALS trial_result · 2012-12-06Clinical Trial Update: The Role Of Gastroesophageal Reflux Disease (GERD) in Eosinophilic Esophagitis [Phase 2, Phase 3]
A Mayo Clinic–led clinical trial update describing Phase 2 and Phase 3 studies on the role of gastroesophageal reflux disease in eosinophili…
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CLINICAL_TRIALS trial_result · 2012-12-03Clinical Trial Update: CYP2C19 Genetic Polymorphism on the Accuracy of Proton-Pump Inhibitor Testing [Phase 4]
Phase 4 study assessing whether CYP2C19 genetic polymorphism affects the accuracy of proton-pump inhibitor testing in gastroesophageal reflu…