Gastroesophageal Junction Adenocarcinoma
📧 Sign up to get email alerts when something new happens for Gastroesophageal Junction Adenocarcinoma.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors [Phase 1]
This update reports on a Phase 1 trial testing the combination of sonidegib and pembrolizumab in patients with various advanced solid tumors…
-
CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 2]
A Phase 2 trial from AstraZeneca is evaluating novel drug combinations in participants with locally advanced unresectable or metastatic gast…
-
CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors [Phase 1]
Phase 1 clinical trial update for AVA6103 in patients with locally advanced or metastatic selected solid tumors; the study is currently recr…
-
CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Safety and Pharmacokinetics of Tucatinib (MK-7119) in Chinese Participants With Cancer (MK-7119-002) [Phase 1]
Phase 1 clinical trial MK-7119-002 assesses safety and pharmacokinetics of tucatinib (MK-7119) in Chinese participants with cancer; the stud…
-
CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors [Phase 1, Phase 2]
A Mayo Clinic-sponsored phase 1/2 trial evaluating a personalized neoantigen peptide-based vaccine in combination with pembrolizumab for adv…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: HS-20093 in Patients With Advanced Gastric and Gastroesophageal Junction Adenocarcinoma [Phase 1]
This document notes an ongoing Phase 1 trial of HS-20093 for advanced gastric and gastroesophageal junction adenocarcinoma, with recruitment…
-
CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: A Study of Barrett's Esophagus Patients: Optimization of a Risk Model to Better Predict the Development of Cancer Recurrence and the Effect of Risk Profile Disclosure on Patient Quality of Life and Fear of Cancer [NA]
This clinical trial aims to optimize a risk model to predict cancer recurrence in Barrett's esophagus patients and to study the impact of ri…
-
CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Pembrolizumab and Chemoradiotherapy for the Treatment of Unresectable Gastroesophageal Cancer [Phase 1]
Phase 1 clinical trial at MD Anderson is evaluating the combination of pembrolizumab with chemoradiotherapy for unresectable gastroesophagea…
-
CLINICAL_TRIALS other · 2026-03-04Clinical Trial Update: A Study of AK104 (SC) in Combination With Oxaliplatin and Capecitabine (XELOX) Versus AK104 (IV) in Combination With XELOX in Participants With Unresectable Locally Advanced or Metastatic Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma [Phase 3]
Phase 3 clinical trial comparing AK104 given subcutaneously with XELOX vs AK104 given intravenously with XELOX in unresectable locally advan…
-
CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer [Phase 1]
A Phase 1 clinical trial evaluating the combination of Lonsurf (trifluridine/tipiracil) and Talzenna (talazoparib) for locally advanced or m…
-
CLINICAL_TRIALS trial_result · 2026-02-24Clinical Trial Update: Efficacy and Survival Analysis of Perioperative Treatment of Locally Advanced Gastric or Gastroesophageal Junction Cancer
This clinical trial update evaluates the efficacy and survival outcomes of perioperative treatment for locally advanced gastric or gastroeso…
-
CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Real-WorlD ZolbetUximab in Patients With HER-2 Negative and CLaudin 18.2 PosItive MetastatiC AdEnocarcinoma
This clinical trial update describes a real-world study of zolbetuximab in patients with HER-2 negative, Claudin-18.2–positive metastatic ga…
-
CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Bemarituzumab or Placebo Plus Chemotherapy in Gastric Cancers With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression [Phase 3]
Phase 3 trial evaluating bemarituzumab plus chemotherapy versus placebo plus chemotherapy in FGFR2b-overexpressing gastric and gastroesophag…
-
CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Perioperative Chemotherapy With Low-Dose Radiotherapy and Tislelizumab for Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 2]
Phase 2 trial evaluating perioperative chemotherapy with low-dose radiotherapy and tislelizumab for locally advanced gastric or gastroesopha…
-
CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Ph1b/2 Study of the Safety and Efficacy of SHR-A1811 Combinations in Advanced HER2 Expression Gastric Cancer [Phase 2]
This document provides an update on an ongoing Phase 1b/2 clinical trial evaluating SHR-A1811 combinations in advanced HER2-expressing gastr…
-
CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors [Phase 1]
Phase 1 study update for NRM-823 in locally advanced or metastatic refractory solid tumors, currently recruiting. The trial lists head and n…
-
CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: A Study of Trastuzumab DeRuxtecan for Patients With Advanced HER2-pOsitive GaStric or GastroesoPhageal Junction AdEnocarcinoma Who Have Received a PrIor Trastuzumab-based Regimen Accompanied by a Disease RegistrY of Patients Treated With Conventional Therapies (PROSPERITY)
This clinical trial update announces ongoing recruitment for a study of trastuzumab deruxtecan in adults with HER2-positive advanced gastric…
-
CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: A Phase III Clinical Study of Cadonilimab Plus SOX as Perioperative Treatment for Patients With Resectable G/GEJ Adenocarcinoma [Phase 3]
A Phase III clinical trial is evaluating Cadonilimab in combination with the SOX chemotherapy regimen as perioperative treatment for patient…
-
CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Megestrol Acetate Oral Suspension for Cachexia in Patients With cStage III Gastric/Gastroesophageal Junction Adenocarcinoma Receiving Neoadjuvant Therapy With Serplulimab Combined With SOX [Phase 2]
Phase 2 trial update for Megestrol Acetate oral suspension to manage cancer cachexia in patients with stage III gastric cancer or gastroesop…
-
CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: LM-302 for the Treatment of Subjects With Claudin18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma. [Phase 3]
LM-302 is being evaluated in a Phase 3 trial for Claudin18.2-positive gastric and gastroesophageal junction adenocarcinoma; the study is cur…
-
CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Abemaciclib Plus Ramucirumab for Esophageal/Gastroesophageal Junction Ca [Phase 1, Phase 2]
An ongoing Phase 1/2 study of abemaciclib plus ramucirumab for metastatic esophageal adenocarcinoma and metastatic gastroesophageal junction…
-
CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Study of Sequential Systemic Therapy + Intraperitoneal Paclitaxel in Gastric/GEJ Peritoneal Carcinomatosis [Phase 2]
This Phase 2 clinical trial assesses sequential systemic therapy followed by intraperitoneal paclitaxel for gastric cancer with peritoneal c…
-
CLINICAL_TRIALS other · 2026-02-03Clinical Trial Update: SHR-1701 Combined With Chemotherapy for Gastric or Gastroesophageal Junction Adenocarcinoma With Peritoneal Metastasis [Phase 2]
Phase 2 trial evaluating SHR-1701 in combination with chemotherapy for gastric adenocarcinoma or gastroesophageal junction adenocarcinoma wi…
-
CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Phase I/II Study of Perioperative Chemotherapy Plus Immunotherapy Followed by Surgery in Localized Esophageal and Gastroesophageal Adenocarcinoma [Phase 2]
A Phase 2 study from MD Anderson evaluating perioperative chemotherapy plus immunotherapy followed by surgery for localized esophageal adeno…
-
CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Camrelizumab Combined With or Without Apatinib and SOX of Neoadjuvant Treatment for Gastric Cancer [Phase 2]
Phase 2 neoadjuvant trial evaluating camrelizumab with or without apatinib plus SOX chemotherapy for gastric or gastroesophageal junction ad…