Gastroesophageal Junction Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-03Clinical Trial Results: A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer) [Phase 1, Phase 2]
Phase 1/2 study evaluating multiple immunotherapy-based combinations in locally advanced unresectable or metastatic gastric/GEJ cancer and e…
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CLINICAL_TRIALS trial_result · 2026-07-07Clinical Trial Update: Neoadjuvant RCT Versus CT for Patients With Locally Advanced, Potentially Resectable Adenocarcinoma of the GEJ [Phase 3]
Phase 3 neoadjuvant trial comparing neoadjuvant therapy to chemotherapy for locally advanced, potentially resectable gastroesophageal juncti…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Phase 1/2 Study of BHB810 in Advanced Gastric and GEJ Adenocarcinoma [Phase 1, Phase 2]
Clinical trial update indicates a Phase 1/2 study of BHB810 in advanced gastric and GEJ adenocarcinoma, with the trial currently not yet rec…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Trastuzumab Deruxtecan Plus Nivolumab Plus Capecitabine Plus Oxaliplatin for HER2 Low Gastric and Gastroesophageal Junction Adenocarcinoma [Phase 1, Phase 2]
A Phase 1/2 trial evaluating trastuzumab deruxtecan in combination with nivolumab, capecitabine, and oxaliplatin for HER2-low gastric and ga…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery [Phase 2, Phase 3]
A phase 2/3 trial of Nivolumab and Ipilimumab in esophageal and gastroesophageal junction adenocarcinoma undergoing surgery is currently sus…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Clinical Study of Regorafenib and Nivolumab Plus Chemotherapy [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical study of regorafenib and nivolumab plus chemotherapy for gastric and gastroesophageal junction adenocarcinoma (an…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Trial of Neoadjuvant Durvalumab Plus Docetaxel, Oxaliplatin, S-1 Followed by Surgery and Adjuvant Durvalumab Plus S-1 Chemotherapy in Potentially Resectable MMR Proficient Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 2]
Phase 2 trial of neoadjuvant durvalumab plus docetaxel, oxaliplatin and S-1 followed by surgery, with adjuvant durvalumab plus S-1, in poten…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Efficacy of Sintilimab Combined With Bevacizumab and XELOX/SOX in Initially Unresectable AFP-positive Gastric/Gastroesophageal Junction Adenocarcinoma [Phase 2]
Phase 2 clinical trial evaluating sintilimab with bevacizumab and XELOX/SOX in initially unresectable AFP-positive gastric/GEJ adenocarcinom…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Pembrolizumab and Chemoradiotherapy for the Treatment of Unresectable Gastroesophageal Cancer [Phase 1]
Phase 1 clinical trial at MD Anderson is evaluating the combination of pembrolizumab with chemoradiotherapy for unresectable gastroesophagea…
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CLINICAL_TRIALS trial_result · 2026-02-24Clinical Trial Update: Efficacy and Survival Analysis of Perioperative Treatment of Locally Advanced Gastric or Gastroesophageal Junction Cancer
This clinical trial update evaluates the efficacy and survival outcomes of perioperative treatment for locally advanced gastric or gastroeso…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Megestrol Acetate Oral Suspension for Cachexia in Patients With cStage III Gastric/Gastroesophageal Junction Adenocarcinoma Receiving Neoadjuvant Therapy With Serplulimab Combined With SOX [Phase 2]
Phase 2 trial update for Megestrol Acetate oral suspension to manage cancer cachexia in patients with stage III gastric cancer or gastroesop…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Camrelizumab Combined With or Without Apatinib and SOX of Neoadjuvant Treatment for Gastric Cancer [Phase 2]
Phase 2 neoadjuvant trial evaluating camrelizumab with or without apatinib plus SOX chemotherapy for gastric or gastroesophageal junction ad…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: LM-108 in Combination With Toripalimab Versus Paclitaxel Injection for the Treatment of Subjects With CCR8-Positive Gastric and Gastroesophageal Junction Adenocarcinoma [Phase 3]
A Phase 3 clinical trial update for LM-108 in combination with toripalimab versus paclitaxel for CCR8-positive gastric and gastroesophageal …
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Combination of Chemotherapy and Adaptive MR-Guided Radiotherapy to Improve Outcomes in Patients With Esophageal Adenocarcinoma [Phase 1]
A Phase 1 trial assessing the combination of chemotherapy and adaptive MR-guided radiotherapy for esophageal adenocarcinoma and gastroesopha…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Induction FLOT With CROSS CRT for Esophageal Cancer [Phase 2]
A Phase 2 clinical trial evaluating induction FLOT chemotherapy followed by CROSS chemoradiation for esophageal or gastroesophageal junction…
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: GEN-001 in Combination With Avelumab for Patients With PD-L1 Positive Gastric Cancer [Phase 2]
Phase 2 clinical trial update shows GEN-001 in combination with Avelumab for PD-L1 positive gastric cancer and gastroesophageal junction ade…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: A Study of SGN-B6A in Chinese Participants With Advanced Solid Tumors [Phase 1]
A Phase 1 study of SGN-B6A in Chinese participants with advanced solid tumors has completed, reporting safety and preliminary activity acros…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Bemarituzumab Plus Chemotherapy and Nivolumab Versus Chemotherapy and Nivolumab for FGFR2b Overexpressed Untreated Advanced Gastric and Gastroesophageal Junction Cancer. [Phase 3]
A Phase 3 trial evaluating bemarituzumab added to chemotherapy and nivolumab versus chemotherapy and nivolumab in FGFR2b-overexpressing untr…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Biomarker Analysis of Tislelizumab Combined With Chemotherapy for Perioperative Treatment of G/GEJ Adenocarcinoma
Completed clinical trial update reporting biomarker analysis for the tislelizumab-chemotherapy combination as perioperative treatment for ga…
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CLINICAL_TRIALS trial_result · 2025-11-28Clinical Trial Update: Study of ACC-1898 in Adult Participants With Advanced Solid Tumors [Phase 1]
Phase 1 study update for ACC-1898 in adults with advanced solid tumors; the trial is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: A Study of AK104 in the First-line Treatment of Locally Advanced Unresectable or Metastatic G/GEJ Adenocarcinoma [Phase 3]
A Phase 3 trial evaluating AK104 as first-line therapy for locally advanced unresectable or metastatic gastric adenocarcinoma and gastroesop…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Afuresertib +Sintilimab+Chemotherapy in Patients With Selected Solid Tumors That Resistance to Prior Anti-PD-1/PD-L1 [Phase 1, Phase 2]
A phase 1/2 trial evaluating afuresertib in combination with sintilimab and chemotherapy in selected solid tumors resistant to prior PD-1/PD…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Phase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid Tumors [Phase 1]
Phase 1a/1b study of TPST-1495 as monotherapy and in combination with pembrolizumab has completed status, spanning multiple solid tumors inc…
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers [Phase 2]
Phase 2 trial evaluating tucatinib plus trastuzumab with oxaliplatin-based chemotherapy or pembrolizumab-containing regimens for HER2-positi…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Durvalumab, an Anti-PDLI Antibody, and Tremelimumab, an Anti-CTLA4 Antibody, and Chemoradiation Before Surgery for Esophageal Cancer [Phase 1, Phase 2]
A phase 1/2 trial is evaluating durvalumab and tremelimumab with chemoradiation before surgery for esophageal and gastroesophageal junction …