Gastroesophageal Junction Adenocarcinoma

• CLINICAL_TRIALS trial_result · 2023-03-15
  Clinical Trial Update: TAS 102 in Combination With Ramucirumab in Advanced, Refractory Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma [Phase 2]

  Phase 2 trial evaluating TAS-102 in combination with ramucirumab for advanced, refractory gastric or gastroesophageal junction adenocarcinom…

• CLINICAL_TRIALS trial_result · 2023-03-02
  Clinical Trial Update: A Study of Sintilimab Plus Ramucirumab as First-line Treatment for G/EGJ Adenocarcinoma (ORIENT-106) [Phase 3]

  A Phase 3 trial evaluating sintilimab plus ramucirumab as first-line treatment for gastric/gastroesophageal junction adenocarcinoma was term…

• CLINICAL_TRIALS trial_result · 2022-09-08
  Clinical Trial Update: Cinrebafusp Alfa in Combination With Ramucirumab and Paclitaxel in HER2-High Gastric or GEJ Adenocarcinoma and in Combination With Tucatinib in HER2-Low Gastric or GEJ Andenocarinoma [Phase 2]

  Phase 2 trial update for Cinrebafusp Alfa combined with ramucirumab and paclitaxel in HER2-high gastric/GEJ adenocarcinoma, and Cinrebafusp …

• CLINICAL_TRIALS trial_result · 2022-09-07
  Clinical Trial Update: Bevacizumab and Combination Chemotherapy Before Surgery in Treating Patients With Locally Advanced Esophageal or Stomach Cancer [Phase 2]

  Phase 2 trial evaluating bevacizumab with combination chemotherapy before surgery for locally advanced esophageal or gastroesophageal juncti…

• CLINICAL_TRIALS trial_result · 2022-09-06
  Clinical Trial Update: Tirelizumab in Combination With Chemoradiation in Patients With Unresectable Gastric Cancer or Gastroesophageal Junction Adenocarcinoma [Phase 2]

  Phase 2 clinical trial investigating tirelizumab in combination with chemoradiation for unresectable locally advanced gastric cancer or gast…

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• CLINICAL_TRIALS trial_result · 2022-08-25
  Clinical Trial Update: Pembrolizumab, Combination Chemotherapy, and Radiation Therapy Before Surgery in Treating Adult Patients With Locally Advanced Gastroesophageal Junction or Gastric Cardia Cancer That Can Be Removed by Surgery [Phase 1, Phase 2]

  A Phase 1/2 study evaluating pembrolizumab with chemotherapy and radiation before surgery for locally advanced gastroesophageal junction or …

• CLINICAL_TRIALS trial_result · 2022-08-18
  Clinical Trial Update: Fruquintinib Combined With Toripalimab and SOX Regimen in the First-line Treatment of Advanced Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 1, Phase 2]

  A phase 1/2 trial evaluating Fruquintinib with Toripalimab and SOX chemotherapy as first-line treatment for advanced/metastatic gastric or g…

• CLINICAL_TRIALS trial_result · 2022-08-08
  Clinical Trial Update: A Study of Pembrolizumab (MK-3475) in Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (MK-3475-059/KEYNOTE-059) [Phase 2]

  Phase 2 trial of pembrolizumab in recurrent or metastatic gastric or gastroesophageal junction adenocarcinoma has completed with results pos…

• CLINICAL_TRIALS trial_result · 2022-07-20
  Clinical Trial Update: A Prospective, Single Center Clinical Study of Toripalimab Combined With FLOT Regimen for Perioperative Treatment of PD-L1 Positive Locally Advanced Resectable Gastric Cancer or Gastroesophageal Junction Adenocarcinoma (GEJ) [Phase 2]

  Phase 2 clinical trial evaluating toripalimab plus FLOT as perioperative treatment for PD-L1 positive locally advanced resectable gastric ca…

• CLINICAL_TRIALS trial_result · 2022-07-01
  Clinical Trial Update: A Study of Apatinib Tablets in the Treatment of Advanced or Metastatic Gastric Cancer [Phase 4]

  Phase 4 trial update for apatinib tablets in advanced or metastatic gastric cancer, status completed.

• CLINICAL_TRIALS trial_result · 2022-06-30
  Clinical Trial Update: Pembrolizumab and Palliative Radiation Therapy in Treating Patients With Metastatic Esophagus, Stomach, or Gastroesophageal Junction Cancer [Phase 2]

  A Phase 2 trial evaluating pembrolizumab combined with palliative radiation therapy in patients with metastatic cancers of the esophagus, st…

• CLINICAL_TRIALS trial_result · 2022-06-27
  Clinical Trial Update: Infigratinib in Subjects With GC or GEJ With FGFR2 Amplification or Other Solid Tumors With Other FGFR Alterations [Phase 2]

  Phase 2 trial evaluating Infigratinib in gastric cancer or GEJ adenocarcinoma with FGFR2 amplification or other FGFR alterations; current st…

• CLINICAL_TRIALS trial_result · 2022-04-22
  Clinical Trial Update: Camrelizumab Combined With Apatinib Versus Apatinib Alone in the Third-line Treatment of Metastatic Gastric Cancer [Phase 2]

  Phase 2 trial evaluating camrelizumab plus apatinib versus apatinib alone as third-line treatment for metastatic gastric cancer, status curr…

• CLINICAL_TRIALS trial_result · 2022-03-11
  Clinical Trial Update: Sintilimab and Nab-paclitaxel in Second-line Treatment of Advanced Gastric or Gastro-oesophageal Junction Adenocarcinoma [Phase 2]

  Phase 2 trial evaluating Sintilimab plus nab-paclitaxel as second-line therapy for advanced gastric and gastro-esophageal junction adenocarc…

• CLINICAL_TRIALS trial_result · 2022-02-21
  Clinical Trial Update: Preoperative Concurrent Chemoradiotherapy for Potentially Resectable Adenocarcinoma of the Esophagogastric Junction [Phase 2, Phase 3]

  Clinical trial update for preoperative concurrent chemoradiotherapy in potentially resectable gastroesophageal junction adenocarcinoma compl…

• CLINICAL_TRIALS trial_result · 2022-02-17
  Clinical Trial Update: PEN-866 in Patients With Advanced Solid Malignancies [Phase 1, Phase 2]

  Clinical trial update for PEN-866 across multiple phases investigating advanced solid malignancies, including endometrial adenocarcinoma and…

• CLINICAL_TRIALS trial_result · 2021-11-08
  Clinical Trial Update: Camrelizumab Plus Pyrotinib Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma [Phase 2]

  A Phase 2 trial exploring camrelizumab plus pyrotinib plus chemotherapy for HER2-positive advanced gastric or GEJ adenocarcinoma; current st…

• CLINICAL_TRIALS trial_result · 2021-08-12
  Clinical Trial Update: Tislelizumab Combined With S-1 Plus Oxaliplatin as a Neoadjuvant Treatment in Patients With GC/GEJC [Phase 2]

  Phase 2 trial evaluating tislelizumab with S-1 and oxaliplatin as neoadjuvant therapy for advanced gastric cancer and advanced gastroesophag…

• CLINICAL_TRIALS trial_result · 2021-08-03
  Clinical Trial Update: A Study of Paclitaxel With or Without Ramucirumab (LY3009806) in Participants With Gastric or Gastroesophageal Cancer [Phase 3]

  Phase 3 trial assessing paclitaxel with or without ramucirumab in gastric or gastroesophageal junction adenocarcinoma has completed with res…

• CLINICAL_TRIALS trial_result · 2021-05-17
  Clinical Trial Update: Apatinib Plus Camrelizumab Combined With Docetaxel and S1 in First-line Treatment for Metastatic Gastric Cancer [Phase 2]

  Phase 2 trial evaluating apatinib plus camrelizumab with docetaxel and S1 as first-line therapy for metastatic gastric/gastroesophageal junc…

• CLINICAL_TRIALS trial_result · 2021-05-04
  Clinical Trial Update: Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer [Phase 3]

  Phase 3 trial evaluating radiation therapy with paclitaxel and carboplatin with or without trastuzumab in esophageal and gastroesophageal ju…

• CLINICAL_TRIALS trial_result · 2021-05-04
  Clinical Trial Update: Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer [Phase 3]

  Phase 3 trial evaluating radiation therapy with paclitaxel and carboplatin with or without trastuzumab in esophageal cancer (NCT01196390) ha…

• CLINICAL_TRIALS trial_result · 2021-03-26
  Clinical Trial Update: Trial of S-1 Maintenance Therapy in Metastatic Esophagogastric Cancer [Phase 2]

  Phase 2 trial evaluating S-1 maintenance therapy in unresectable, locally advanced or metastatic gastric/GEJ adenocarcinoma has been complet…

• CLINICAL_TRIALS trial_result · 2021-02-01
  Clinical Trial Update: Raltitrexed and Paclitaxel for Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 2]

  Phase 2 trial evaluating raltitrexed with paclitaxel for gastric cancer and gastroesophageal junction adenocarcinoma has completed.

• CLINICAL_TRIALS trial_result · 2020-12-24
  Clinical Trial Update: Study to Evaluate the Safety and Tolerability of Andecaliximab as Monotherapy and in Combination With Anti-Cancer Agents in Japanese Participants With Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 1]

  Phase 1 trial evaluating andecaliximab as monotherapy and with anti-cancer agents in Japanese patients with gastric or gastroesophageal junc…