Gastroesophageal Junction Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Pan-tumor MRD Study
Paradigm Health's Pan-tumor MRD study (NCT06605404) is currently recruiting across several solid tumor indications including bladder, esopha…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06) [Phase 2, Phase 3]
Clinical trial update on evorpacept (ALX148) for advanced HER2-positive gastric cancer (ASPEN-06) noting that Phase 2 and Phase 3 cohorts ar…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer [Phase 2]
Phase 2 clinical trial evaluating TRK-950 in combination with ramucirumab and paclitaxel for gastric cancer in recruiting status.
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Novel SEQUEnced Immunotherapy With Anti-angiogenesis and Chemotherapy in Advanced gastroesophageaL Adenocarcinoma [Phase 2]
A Phase 2 clinical trial update for sequential immunotherapy combining anti-angiogenesis and chemotherapy in advanced gastroesophageal junct…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Study of Atezolizumab + FLOT vs. FLOT Alone in Patients With GC/GEJ and High Immune Responsiveness [Phase 2]
Phase 2 study evaluating atezolizumab added to the FLOT chemotherapy regimen versus FLOT alone in patients with gastric cancer or gastroesop…
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: A Study of Minimally Invasive Proximal Gastrectomy Versus Minimally Invasive Total Gastrectomy for Gastric and Gastroesophageal Junction Cancers
A clinical trial comparing minimally invasive proximal gastrectomy versus minimally invasive total gastrectomy for gastric and gastroesophag…
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: Tislelizumab Plus FOLFOX Versus POF in the Treatment of Locally Advanced: a Multicenter, Open-label, Randomized Phase III Studyunresectable or Metastatic Gastric/Gastroesophageal Junction Adenocarcinoma [Phase 3]
A multicenter, open-label Phase III study randomizes tislelizumab plus FOLFOX versus POF in locally advanced or metastatic gastric and gastr…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Fruquintinib in Combination With Sintilimab and CAPEOX as First-line Treatment for G/GEJ Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating a triplet of Fruquintinib, Sintilimab, and the CAPEOX chemotherapy regimen as first-line therapy fo…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Pembrolizumab and Trifluridine/Tipiracil With Previously Treated Advanced Gastric Cancer [Phase 1, Phase 2]
This clinical trial evaluates the combination of pembrolizumab with trifluridine/tipiracil in patients with previously treated advanced gast…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Neoadjuvant Cadonilimab Combined With Perioperative Oxaliplatin Plus S1 for Diffuse or Mixed Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma [Phase 3]
Phase 3 trial evaluating neoadjuvant cadonilimab plus perioperative oxaliplatin and S-1 for diffuse or mixed-type locally advanced gastric/G…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Real-world Effectiveness and Safety of Trastuzumab Deruxtecan in Patients With Locally Advanced or Metastatic HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma in China
This clinical trial update describes a real-world evaluation of trastuzumab deruxtecan in Chinese patients with HER2-positive gastric or gas…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors [Phase 2]
Phase 2 study evaluating APL-101 in non-small cell lung cancer with MET exon 14 skipping mutations and MET dysregulation, as well as other M…
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Perioperative Treatment of Combined Radiotherapy With SOX, Apatinib and Camrelizumab for Oesophagogastric Cancer [Phase 2]
Phase 2 trial evaluating perioperative radiotherapy combined with SOX (S-1 and oxaliplatin), apatinib, and camrelizumab for gastric and gast…
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: Sintilimab Plus Apatinib and SOX as First-line Treatment in Patients With AFP Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 2]
Phase 2 clinical trial evaluating first-line sintilimab plus apatinib and S-1 with oxaliplatin (SOX) in AFP-producing gastric or gastroesoph…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Study to Evaluate the Efficacy, Safety and Pharmacokinetics of CT041 Autologous CAR T-cell Injection [Phase 1, Phase 2]
This update describes an ongoing Phase 1/2 clinical trial evaluating CT041 autologous CAR T-cell therapy for gastric adenocarcinoma, gastroe…
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CLINICAL_TRIALS research · 2025-06-02Clinical Trial Update: Timing of Minimally Invasive Local Treatment After First-Line Systemic Therapy in Oligometastatic Esophageal or Gastric Adenocarcinoma [Phase 2, Phase 3]
This clinical trial update outlines a Phase 2/Phase 3 study evaluating the timing of minimally invasive local treatment following first-line…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Relationship Between Perioperative Treatment Efficacy and The Tumor Microenvironment for Locally Advanced Resectable Gastric Cancer.
This clinical trial update discusses how perioperative treatment efficacy may be influenced by the tumor microenvironment in locally advance…
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Adebrelimab With Chemoradiotherapy and Surgery for G/GEJ [Phase 2]
Phase 2 clinical trial evaluating Adebrelimab in combination with chemoradiotherapy and surgery for gastroesophageal junction and gastric ad…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Efficacy and Safety of Fruquintinib Combined With Sintilimab and Stereotactic Body Radiation Therapy (SBRT) for the Second-line and Higher-line Treatment of Gastric or Gastroesophageal Junction Adenocarcinoma With Oligometastatic Progression [Phase 2, Phase 3]
A clinical trial update describing a Phase 2/3 study evaluating Fruquintinib plus Sintilimab and SBRT for second-line or higher treatment of…
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Total Neoadjuvant FLOT Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Cancer [Phase 2, Phase 3]
A Phase 2/Phase 3 trial is evaluating total neoadjuvant FLOT chemotherapy for locally advanced gastric and gastroesophageal junction cancer;…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: Combination of QLS31905, QL2107 and Chemotherapy as First-line Therapy in CLDN18.2-positive Unresectable Locally Advanced or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma [Phase 2]
Phase 2 study evaluating a combination of QLS31905, QL2107, and chemotherapy as first-line therapy for CLDN18.2-positive unresectable locall…
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: A Study of Disitamab Vedotin Combined With Tislelizumab and Chemotherapy Versus Tislelizumab Combined With Chemotherapy in HER2-Low Advanced Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 3]
Phase 3 clinical trial update evaluating disitamab vedotin plus tislelizumab and chemotherapy versus tislelizumab and chemotherapy in HER2-l…
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: Neoadjuvant Apatinib Combined With Sintilimab and Perioperative SOX Versus Neoadjuvant Sintilimab Combined With Perioperative SOX for Intestinal Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma [Phase 3]
This Phase 3 clinical trial assesses whether adding apatinib to sintilimab and perioperative SOX improves outcomes versus sintilimab plus pe…
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Phase II Trial of Iparomlimab/Tuvonralimab (QL1706) + XELOX in HER2-Negative, Low PD-L1 G/GEJ Adenocarcinoma [Phase 2]
Phase II trial evaluating Iparomlimab/Tuvonralimab (QL1706) with XELOX in HER2-negative, low PD-L1 expressing unresectable or metastatic gas…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Fruquintinib Combined With PD-1 Inhibitor as First-line Maintenance Therapy for Advanced Gastric Cancer [Phase 2]
Phase 2 trial update evaluating fruquintinib in combination with a PD-1 inhibitor as first-line maintenance therapy for advanced gastric can…