Gastroesophageal Junction Adenocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Perioperative Chemotherapy With Low-Dose Radiotherapy and Tislelizumab for Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 2]
Phase 2 trial evaluating perioperative chemotherapy with low-dose radiotherapy and tislelizumab for locally advanced gastric or gastroesopha…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Ph1b/2 Study of the Safety and Efficacy of SHR-A1811 Combinations in Advanced HER2 Expression Gastric Cancer [Phase 2]
This document provides an update on an ongoing Phase 1b/2 clinical trial evaluating SHR-A1811 combinations in advanced HER2-expressing gastr…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors [Phase 1]
Phase 1 study update for NRM-823 in locally advanced or metastatic refractory solid tumors, currently recruiting. The trial lists head and n…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: A Study of Trastuzumab DeRuxtecan for Patients With Advanced HER2-pOsitive GaStric or GastroesoPhageal Junction AdEnocarcinoma Who Have Received a PrIor Trastuzumab-based Regimen Accompanied by a Disease RegistrY of Patients Treated With Conventional Therapies (PROSPERITY)
This clinical trial update announces ongoing recruitment for a study of trastuzumab deruxtecan in adults with HER2-positive advanced gastric…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: A Phase III Clinical Study of Cadonilimab Plus SOX as Perioperative Treatment for Patients With Resectable G/GEJ Adenocarcinoma [Phase 3]
A Phase III clinical trial is evaluating Cadonilimab in combination with the SOX chemotherapy regimen as perioperative treatment for patient…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: LM-302 for the Treatment of Subjects With Claudin18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma. [Phase 3]
LM-302 is being evaluated in a Phase 3 trial for Claudin18.2-positive gastric and gastroesophageal junction adenocarcinoma; the study is cur…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Abemaciclib Plus Ramucirumab for Esophageal/Gastroesophageal Junction Ca [Phase 1, Phase 2]
An ongoing Phase 1/2 study of abemaciclib plus ramucirumab for metastatic esophageal adenocarcinoma and metastatic gastroesophageal junction…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Study of Sequential Systemic Therapy + Intraperitoneal Paclitaxel in Gastric/GEJ Peritoneal Carcinomatosis [Phase 2]
This Phase 2 clinical trial assesses sequential systemic therapy followed by intraperitoneal paclitaxel for gastric cancer with peritoneal c…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Phase I/II Study of Perioperative Chemotherapy Plus Immunotherapy Followed by Surgery in Localized Esophageal and Gastroesophageal Adenocarcinoma [Phase 2]
A Phase 2 study from MD Anderson evaluating perioperative chemotherapy plus immunotherapy followed by surgery for localized esophageal adeno…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Registry Platform Gastric/Esophageal Cancer (SAPHIR)
This Clinical Trial Update reports an ongoing registry platform trial SAPHIR addressing gastric and esophageal cancers, currently recruiting…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Perioperative Ivonescimab Plus S-1 and Oxaliplatin (SOX) for Locally Advanced Gastric or GEJ Adenocarcinoma [Phase 2]
This ClinicalTrials.gov entry describes a Phase 2 perioperative trial of Ivonescimab plus S-1 and oxaliplatin (SOX) for locally advanced gas…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: A Study of KK2269 in Adult Participants With Solid Tumors [Phase 1]
Phase 1 study update for KK2269 in adults with solid tumors; the trial is currently recruiting. Indications include gastric adenocarcinoma, …
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: ASKB589 in Combination With CAPOX and PD-1 Inhibitor in Patients With Advanced or Metastatic GC/GEJ Adenocarcinoma [Phase 3]
Clinical trial update for ASKB589 in combination with CAPOX and a PD-1 inhibitor for advanced or metastatic gastric/gastroesophageal junctio…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Perioperative Treatment of Combined SOX With Apatinib and Camrelizumab for Oesophagogastric Cancer [Phase 2, Phase 3]
A perioperative trial investigating the combination of SOX chemotherapy with Apatinib and Camrelizumab for gastric and gastroesophageal junc…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: First in Human Study of QLS5316 in Solid Tumors [Phase 1]
This is a first-in-human Phase 1 trial of QLS5316 in various solid tumors; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: A Study of Disitamab Vedotin Combined With Trastuzumab and Tislelizumab Versus Chemotherapy Combined With Trastuzumab With or Without Pembrolizumab in HER2-high Expression Advanced Gastric or Gastroesophageal Junction Adenocarcinoma. [Phase 3]
Phase 3 trial evaluating disitamab vedotin with trastuzumab and tislelizumab versus chemotherapy with trastuzumab (with or without pembroliz…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer [Phase 1]
First-in-human phase 1 study of TORL-2-307-ADC in participants with advanced cancer, including gastric cancer, pancreatic cancer, and gastro…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04) [Phase 3]
This clinical trial update reports the Phase 3 DESTINY-Gastric04 study of trastuzumab deruxtecan for HER2-positive gastric cancer or gastroe…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal Adenocarcinoma [Phase 2]
A Phase 2 neoadjuvant trial evaluating intra-tumoral RP2 in combination with the FLOT regimen for gastric and esophageal adenocarcinoma is l…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Pembrolizumab and Lenvatinib for the Treatment of Advanced, Unresectable, or Metastatic Gastroesophageal Adenocarcinoma [EARLY_Phase 1]
A phase 1 trial is evaluating the combination of pembrolizumab and lenvatinib for advanced, unresectable, or metastatic gastric cancer and g…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Fruquintinib Combined With Trastuzumab and XELOX as First-line Treatment in Patients With HER2-positive Advanced Gastric Cancer [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating Fruquintinib in combination with Trastuzumab and XELOX as first-line thera…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Bemarituzumab in FGFR2b+ Patients With Advanced or Metastatic Adenocarcinoma of the Stomach or Gastroesophageal Junction, Who Failed at Least One Prior Line of Palliative Chemotherapy [Phase 2]
Phase 2 clinical trial evaluating bemarituzumab in FGFR2b-positive advanced or metastatic stomach or gastroesophageal junction adenocarcinom…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Hypofractionated Radiotherapy Plus Immunochemotherapy for Neoadjuvant Treatment of Gastroesophageal Junction Adenocarcinoma [Phase 1, Phase 2]
A Phase 1/2 trial evaluating hypofractionated radiotherapy plus immunochemotherapy as neoadjuvant treatment for gastroesophageal junction ad…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Telehealth for the Self-Management of Dietary Quality of Life in Patients After Stomach Cancer Surgery [NA]
This update describes a telehealth program to help patients manage dietary quality of life after stomach cancer surgery; the study is curren…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Hyperthermic Intraperitoneal Chemotherapy With Cisplatin and Paclitaxel for the Treatment of Patients With Gastric and Gastroesophageal Junction Adenocarcinoma at High Risk of Peritoneal Recurrence [Phase 2]
Phase 2 clinical trial evaluating hyperthermic intraperitoneal chemotherapy with cisplatin and paclitaxel for gastric or gastroesophageal ju…