Functional Mitral Regurgitation
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: ARNI Combined With SGLT2 Inhibitors on Functional Mitral Regurgitation Remodeling
A completed clinical trial (NCT07379788) is evaluating the combination of an ARNI (sacubitril/valsartan) with SGLT2 inhibitors for remodelin…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Atrial Functional Mitral Regurgitation and Tricuspid Regurgitation
This clinical trial update from Barts & The London NHS Trust describes a study on atrial fibrillation with functional mitral regurgitation a…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR [NA]
Clinical trial update for the Carillon Mitral Contour System evaluating treatment of Functional Mitral Regurgitation in heart failure; the s…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial [NA]
Clinical trial update for Edwards Lifesciences' PASCAL CLASP IID/IIF pivotal trial is currently active but not recruiting for Degenerative M…
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation [NA]
The clinical trial assessing the Tendyne Transcatheter Mitral Valve System for symptomatic mitral regurgitation has posted results; the stud…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: AMEND TS Early Feasibility Study [NA]
AMEND TS early feasibility study sponsored by Valcare Medical Ltd. is currently recruiting for symptomatic functional mitral regurgitation g…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance
A clinical trial update describing recruiting status for using MitraClip to treat secondary/functional mitral regurgitation in patients with…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Sacubitril-Valsartan in Heart Failure With Preserved Ejection Fraction and Secondary Mitral Valve Regurgitation [Phase 4]
Phase 4 trial update for sacubitril/valsartan in heart failure with preserved ejection fraction and functional mitral regurgitation. The stu…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Randomized Controlled Study of Dragonfly System for Functional Mitral Regurgitation [NA]
This document reports a randomized controlled trial evaluating the Dragonfly System for functional mitral regurgitation. The trial status is…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: Phenotypic Classification of FMR With CMR
ClinicalTrials.gov update shows a Cleveland Clinic-sponsored recruiting study to phenotype functional mitral regurgitation using cardiac mag…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Catheter Ablation for Functional Mitral Regurgitation in Persistent Atrial Fibrillation: Development and Validation of a Predictive Model-A Multicenter Prospective Cohort Study
This document describes a multicenter prospective cohort trial to develop and validate a predictive model for outcomes of catheter ablation …
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Optimizing Clinical Outcomes in Patients Undergoing Mitral Transcatheter Edge-to-edge Repair (M-TEER) for Severe Functional Mitral Regurgitation Towards Improved Guideline-directed Medical Therapy
Clinical trial investigating optimization of outcomes in patients undergoing mitral transcatheter edge-to-edge repair for severe functional …
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: Bio Refine for Functional Mitral Regurgitation - a Safety & Feasibility Study [NA]
A safety and feasibility study investigating a Bio Refine product for treating functional mitral regurgitation, currently in recruitment.
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CLINICAL_TRIALS other · 2025-02-12Clinical Trial Update: Safety and Effectiveness Study of SQ-Kyrin System for Functional Mitral Regurgitation in EU [NA]
Clinical trial update indicating that the SQ-Kyrin System is recruiting in the European Union for a safety and effectiveness study in functi…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: CAP-TEER: CerebrAl Protection During Transcatheter Edge-to-edge Repair [NA]
The CAP-TEER study is evaluating cerebral protection during transcatheter edge-to-edge repair for mitral regurgitation. The trial is current…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Clinical Evaluation of the Safety and Effectiveness of the MitraClip System in the Treatment of Clinically Significant Functional Mitral Regurgitation [NA]
A completed clinical trial evaluating the safety and effectiveness of the MitraClip System for treating clinically significant functional mi…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: SATURN Transcatheter Mitral Valve Replacement for Functional Mitral Regurgitation [NA]
Clinical trial update for InnovHeart's SATURN transcatheter mitral valve replacement addressing functional mitral regurgitation. The current…
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CLINICAL_TRIALS trial_result · 2023-05-08Clinical Trial Update: Dapagliflozin Effect on FunctiOnal Mitral Regurgitation and Myocardial Fibrosis (DEFORM) [Phase 4]
A Phase 4 trial update on the effect of dapagliflozin for functional mitral regurgitation and myocardial fibrosis.
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CLINICAL_TRIALS trial_result · 2023-03-08Clinical Trial Update: NHLBI DIR Transcatheter Mitral Cerclage Annuloplasty Early Feasibility Study [NA]
An NHLBI-supported early feasibility study evaluates transcatheter mitral cerclage annuloplasty for functional mitral regurgitation. The tri…
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CLINICAL_TRIALS trial_result · 2023-02-28Clinical Trial Update: Dapagliflozin Effect on FunctiOnal Mitral Regurgitation and Myocardial Remodeling [Phase 4]
Phase 4 clinical trial investigating the effects of dapagliflozin on functional mitral regurgitation and myocardial remodeling.
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CLINICAL_TRIALS trial_result · 2022-11-09Clinical Trial Update: Edwards Cardioband System ACTIVE Pivotal Clinical Trial (ACTIVE) [NA]
Clinical trial update for Edwards Cardioband System ACTIVE pivotal trial shows termination with posted results.
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CLINICAL_TRIALS trial_result · 2022-06-14Clinical Trial Update: MitraClip Russia Trial [NA]
Clinical trial update for the MitraClip Russia trial (NCT04350372) by Abbott Medical Devices; the study on functional and degenerative mitra…
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CLINICAL_TRIALS trial_result · 2020-05-06Clinical Trial Update: Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation (The COAPT Trial) and COAPT CAS [NA]
Clinical trial update for the COAPT study and COAPT CAS, assessing cardiovascular outcomes of MitraClip in heart failure patients with funct…
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CLINICAL_TRIALS trial_result · 2019-09-19Clinical Trial Update: AVJ-514 Japan Trial [NA]
Clinical trial update for AVJ-514 in Japan; study completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2018-05-17Clinical Trial Update: Feasibility of the AccuCinch® System for Left Ventricular Reshaping of the Mitral Apparatus to Reduce Functional Mitral Regurgitation and Improve Left Ventricular Function [NA]
This clinical trial update reports on the feasibility of the AccuCinch system to reshape the left ventricle and reduce functional mitral reg…