Frostbite

• CLINICAL_TRIALS research · 2026-03-09
  Clinical Trial Update: Field Study on Intravenous Iloprost for Treatment of Severe Frostbite at High Altitude

  A field study evaluating intravenous iloprost for the treatment of severe frostbite at high altitude. Recruitment has not yet begun.

• CLINICAL_TRIALS research · 2026-02-20
  Clinical Trial Update: Epoprostenol Plus Conventional Therapy in COld and Frostbite Injury (ECCO) [Phase 4]

  Phase 4 clinical trial evaluating epoprostenol in addition to conventional therapy for frostbite injury; the study is not yet recruiting.

• CLINICAL_TRIALS trial_result · 2026-01-07
  Clinical Trial Update: Outcomes From Hyperbaric Oxygen (HBO2) Treatment for Emerging Indications [Phase 4]

  This Phase 4 update reports outcomes from hyperbaric oxygen therapy across several emerging indications, with the study currently not yet re…

• CLINICAL_TRIALS research · 2026-01-06
  Clinical Trial Update: Comparison of ICG Microangiography and Conventional Angiography in Severe Frostbite

  A clinical trial update for a study comparing indocyanine green (ICG) microangiography with conventional angiography in severe frostbite to …

• CLINICAL_TRIALS trial_result · 2025-12-30
  Clinical Trial Update: Multicenter Sous Vide Frostbite [NA]

  A multicenter clinical trial evaluating a frostbite treatment has completed, and its results were posted on 2025-12-30.

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• CLINICAL_TRIALS withdrawal · 2024-06-14
  Clinical Trial Update: Treatment of Frostbite Sequelae With Botulinum Toxin A [Phase 2]

  Phase 2 trial evaluating botulinum toxin A for frostbite sequelae has been withdrawn.

• CLINICAL_TRIALS trial_result · 2024-05-13
  Clinical Trial Update: Prevention and Treatment of Frostbite Infection With Antimicrobial Pharmacokinetic Analysis [Phase 4]

  A Phase 4 clinical trial is evaluating prevention and treatment of frostbite infection using antimicrobial pharmacokinetic analysis. The stu…

• CLINICAL_TRIALS trial_result · 2021-09-28
  Clinical Trial Update: Sous Vide Rewarming for Frostbitten Extremities [NA]

  Clinical trial completed evaluating sous vide rewarming for frostbitten extremities; results posted in 2021.