Fontan Physiology

• CLINICAL_TRIALS research · 2026-04-08
  Clinical Trial Update: Home Exercise And Resiliency Training (Heart) Club [NA]

  A University of Michigan clinical trial update for Home Exercise and Resiliency Training in Fontan physiology and frailty; the study is curr…

• CLINICAL_TRIALS research · 2025-11-17
  Clinical Trial Update: Blood Based Assessment of sST2, Taken During and After Surgery, for Pediatric Patients With Heart Defects to Predict Heart Failure.

  A pediatric clinical trial is evaluating a blood biomarker (sST2) measured during and after congenital heart surgery to predict heart failur…

• CLINICAL_TRIALS research · 2025-11-14
  Clinical Trial Update: Study of Tadalafil vs. Placebo for Improving Hemodynamics and End-Organ Dysfunction in Fontan Physiology [Phase 3]

  A Phase 3 trial compares tadalafil versus placebo to improve hemodynamics and end-organ function in Fontan physiology. The study is currentl…

• CLINICAL_TRIALS trial_result · 2025-05-14
  Clinical Trial Update: The Hemodynamic Effects of Vasopressin in Patients With Fontan Physiology [EARLY_Phase 1]

  This early Phase 1 trial evaluated the hemodynamic effects of vasopressin in patients with Fontan physiology and hypotension. The study stat…

• CLINICAL_TRIALS research · 2025-05-14
  Clinical Trial Update: Effects of Different Tidal Volume Ventilation Strategies on Fontan Flow and Hemodynamics [NA]

  A completed Stanford-sponsored clinical trial evaluating how different tidal volume ventilation strategies affect Fontan flow and hemodynami…

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• CLINICAL_TRIALS trial_result · 2021-08-25
  Clinical Trial Update: Nitrate Effect on Exercise Capacitance [Phase 2]

  Phase 2 trial evaluating nitrate effects on exercise capacity in Fontan patients has completed with results posted.

• CLINICAL_TRIALS trial_result · 2018-06-01
  Clinical Trial Update: Feasibility and Efficacy of Portable Non-invasive Negative Pressure Ventilation in Fontan Patients [Phase 1]

  Phase 1 study evaluating the feasibility and efficacy of portable non-invasive negative pressure ventilation in patients with Fontan physiol…