Fontan Circulation
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Venous Compression in Fontan [NA]
A clinical trial update describing a study of venous compression in Fontan circulation for individuals with single-ventricle physiology; the…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Muscle Function in Patients With Single-chamber Heart
An update on a clinical trial evaluating muscle function in patients with Fontan circulation (single-ventricle heart). The study status is N…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Gut, Inflammation and Nutrition in Adult Patients After Fontan Operation
This clinical trial evaluated gut health, inflammation, and nutrition in adult patients after Fontan operation; the study is completed.
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry
Clinical trial update for an international registry evaluating the effectiveness of SGLT2 inhibitors in adults with congenital heart disease…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: IMProving DRug Dosing and Outcomes for Single VEntricle Patients With Fontan Associated Liver Disease [Phase 1]
A Phase 1 clinical trial updating on drug dosing and outcomes for single-ventricle patients with Fontan-associated liver disease; recruitmen…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: CAMEO-FONTAN -Dapagliflozin in the Failing Fontan Circulation [Phase 2]
Phase 2 trial of dapagliflozin in patients with failing Fontan circulation is currently recruiting. The study also considers effects in sing…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Cardiac Magnetic Resonance Stress-perfusion Study in Patinets with Fontan Circulation
Karolinska Institutet reports a clinical trial evaluating cardiac magnetic resonance stress-perfusion in patients with Fontan circulation (s…
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CLINICAL_TRIALS research · 2024-10-16Clinical Trial Update: Fontan Circulation and Reproductive Health in a National Swedish Cohort
A national Swedish cohort study is recruiting to examine how Fontan circulation affects reproductive health in individuals with single-ventr…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Theophylline Effects in the Fontan Circulation [Phase 2]
Phase 2 clinical trial assessing theophylline effects in individuals with Fontan circulation due to congenital heart disease has completed.
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CLINICAL_TRIALS trial_result · 2023-03-07Clinical Trial Update: An Upcoming Clinical Study to Measure the Safety and Impact of a Drug Called Macitentan in Teenage and Adult Fontan Patients. [Phase 3]
A Phase 3 trial evaluating safety and impact of macitentan in teenage and adult Fontan patients was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2021-07-09Clinical Trial Update: TRPV2 Agonists in the Fontan Circulation [Phase 4]
Phase 4 trial evaluating TRPV2 agonists in patients with Fontan circulation has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: The Effects of Sildenafil on Exercise Function and Capacity in Patients With Fontan Circulation [Phase 4]
Phase 4 trial evaluating how sildenafil affects exercise function and capacity in patients with Fontan circulation has completed and results…
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CLINICAL_TRIALS trial_result · 2018-12-07Clinical Trial Update: Study of Effects of Sildenafil on Patients With Fontan Heart Circulation [Phase 4]
Phase 4 clinical trial updating the effects of sildenafil in patients with Fontan circulation (single ventricle heart disease) after Fontan …
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: Effect of Tadalafil on Exercise Capacity in Pediatric Fontan Patients [Phase 1]
A Phase 1 trial assessing tadalafil on exercise capacity in pediatric Fontan patients with single-ventricle physiology has completed.