Follicular Lymphoma

• CLINICAL_TRIALS trial_result · 2015-03-26
  Clinical Trial Update: Rituximab Plus CAMPATH in Patients With Relapsed/Refractory Low-Grade or Follicular, CD20-positive, B-cell NHL [Phase 1, Phase 2]

  A Phase 1/2 trial of rituximab plus CAMPATH in relapsed/refractory CD20-positive B-cell non-Hodgkin lymphoma was terminated.

• CLINICAL_TRIALS trial_result · 2015-03-06
  Clinical Trial Update: First in Human Study to Determine the Safety, Tolerability and Preliminary Efficacy of an Anti-CXCR4 Antibody in Subjects With Acute Myelogenous Leukemia and Selected B-cell Cancers [Phase 1]

  First-in-human Phase 1 trial assessing safety, tolerability, and preliminary efficacy of an anti-CXCR4 antibody in acute myeloid leukemia an…

• CLINICAL_TRIALS trial_result · 2015-02-23
  Clinical Trial Update: Feasibility Study of a 60 Minute Rapid Infusion Rituximab Protocol in Patients With B-cell Malignancies [Phase 2]

  A Phase 2 feasibility study evaluating a 60-minute rapid infusion rituximab protocol in patients with indolent or intermediate-grade B-cell …

• CLINICAL_TRIALS trial_result · 2015-01-27
  Clinical Trial Update: Rituximab, Cyclophosphamide, Bortezomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Low-Grade Follicular Lymphoma, Waldenstrom Macroglobulinemia, or Mantle Cell Lymphoma [Phase 2]

  Phase 2 clinical trial evaluating rituximab, cyclophosphamide, bortezomib, and dexamethasone in relapsed/refractory low-grade follicular lym…

• CLINICAL_TRIALS withdrawal · 2015-01-19
  Clinical Trial Update: Comparative Trial for Pixantrone in Combination With Rituximab in Indolent Non-Hodgkin's Lymphoma [Phase 3]

  A Phase 3 trial evaluating pixantrone in combination with rituximab for indolent non-Hodgkin lymphoma was terminated.

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• CLINICAL_TRIALS trial_result · 2014-12-23
  Clinical Trial Update: Bortezomib and Flavopiridol in Treating Patients With Recurrent or Refractory Indolent B-Cell Neoplasms [Phase 1]

  A Phase 1 trial evaluating the combination of bortezomib and flavopiridol in patients with recurrent or refractory indolent B-cell neoplasms…

• CLINICAL_TRIALS trial_result · 2014-12-12
  Clinical Trial Update: A Study of Rituximab and Bevacizumab in Patients With Follicular Non-Hodgkin's Lymphoma [Phase 2]

  Phase 2 clinical trial evaluating rituximab in combination with bevacizumab in patients with follicular lymphoma; results have been posted a…

• CLINICAL_TRIALS trial_result · 2014-12-04
  Clinical Trial Update: A Study of MabThera (Rituximab) in Elderly Patients With Untreated Follicular Non-Hodgkin's Lymphoma (NHL) [Phase 3]

  Phase 3 trial evaluating Rituximab (MabThera) in elderly patients with untreated follicular lymphoma has completed. Results from the study h…

• CLINICAL_TRIALS trial_result · 2014-10-23
  Clinical Trial Update: Phase II Cancer Vaccine Trial for Patients With Follicular Lymphoma [Phase 2]

  A Phase II cancer vaccine trial for Follicular Lymphoma has completed enrollment with the study status marked as completed.

• CLINICAL_TRIALS trial_result · 2014-10-06
  Clinical Trial Update: Fenretinide and Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]

  This ClinicalTrials.gov update reports a terminated phase 1/2 trial evaluating fenretinide with rituximab for B-cell non-Hodgkin lymphomas; …

• CLINICAL_TRIALS trial_result · 2014-09-04
  Clinical Trial Update: Efficacy and Safety Study of Idelalisib in Participants With Indolent B-Cell Non-Hodgkin Lymphomas [Phase 2]

  Phase 2 trial assessing idelalisib for indolent B-cell non-Hodgkin lymphomas completed with results posted in 2014.

• CLINICAL_TRIALS trial_result · 2014-09-01
  Clinical Trial Update: Agatolimod Sodium, Rituximab, and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Recurrent or Refractory Non-Hodgkin Lymphoma [Phase 1, Phase 2]

  A Phase 1/2 clinical trial evaluating agatolimod sodium in combination with rituximab and Yttrium-90 ibritumomab tiuxetan for adults with re…

• CLINICAL_TRIALS trial_result · 2014-08-27
  Clinical Trial Update: Vorinostat and Decitabine in Treating Patients With Advanced Solid Tumors or Relapsed or Refractory Non-Hodgkin's Lymphoma, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Chronic Myelogenous Leukemia [Phase 1]

  Phase 1 trial of vorinostat combined with decitabine in adults with advanced solid tumors or relapsed/refractory hematologic cancers, includ…

• CLINICAL_TRIALS trial_result · 2014-08-06
  Clinical Trial Update: Iodine I 131 Tositumomab and Fludarabine Phosphate in Treating Older Patients Who Are Undergoing an Autologous or Syngeneic Stem Cell Transplant for Relapsed or Refractory Non-Hodgkin's Lymphoma [Phase 1]

  Phase 1 trial update evaluating the combination of iodine-131 tositumomab with fludarabine phosphate in older patients undergoing autologous…

• CLINICAL_TRIALS trial_result · 2014-07-30
  Clinical Trial Update: Ofatumumab and Bortezomib in Subjects With Relapsed CD20+Diffuse Large B Cell, Follicular, or Mantle Cell Lymphoma [Phase 2]

  Phase 2 trial evaluating the combination of ofatumumab and bortezomib in adults with relapsed CD20-positive lymphomas, including diffuse lar…

• CLINICAL_TRIALS research · 2014-07-24
  Clinical Trial Update: S8809-S9800-S9911-S9704-A Study of Blood and Tissue Samples From Patients With Follicular Lymphoma Treated With Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone

  A completed clinical trial update focusing on blood and tissue samples from patients with follicular lymphoma treated with Rituximab, Cyclop…

• FDA approval · 2014-07-23
  FDA Approved: ZYDELIG — Original Application (Gilead Sciences, Inc.)

  FDA approved ZYDELIG (idelalisib) from Gilead Sciences as a new molecular therapy for adults with relapsed or refractory follicular lymphoma…

• CLINICAL_TRIALS trial_result · 2014-07-01
  Clinical Trial Update: Imexon for Relapsed Follicular and Aggressive Lymphomas [Phase 2]

  Phase 2 clinical trial results for imexon in relapsed follicular lymphoma and various aggressive B-cell lymphomas have been completed with r…

• CLINICAL_TRIALS trial_result · 2014-06-25
  Clinical Trial Update: A Study of MabThera/Rituxan (Rituximab) Alone and in Combination With Roferon-A in Patients With Follicular or Other CD20+ Low-Grade (Indolent) Lymphoma [Phase 3]

  Phase 3 trial evaluating rituximab alone and in combination with Roferon-A (interferon alfa) in follicular and other CD20+ indolent lymphoma…

• CLINICAL_TRIALS trial_result · 2014-05-20
  Clinical Trial Update: Velcade (Bortezomib, PS-341) and Rituximab in Relapsed/Refractory Mantle Cell and Follicular Non-Hodgkin's Lymphoma [Phase 2]

  A Phase 2 trial evaluating Velcade (bortezomib) in combination with rituximab for relapsed/refractory mantle cell lymphoma and follicular no…

• CLINICAL_TRIALS trial_result · 2014-05-12
  Clinical Trial Update: Immunochemotherapy, Zevalin, and Bone Marrow Transplant for Follicular Lymphoma [Phase 2]

  Phase 2 trial evaluating immunochemotherapy with Zevalin (ibritumomab tiuxetan) and bone marrow transplant for follicular lymphoma has compl…

• CLINICAL_TRIALS trial_result · 2014-05-09
  Clinical Trial Update: S8947-9800-9911-0016A Vitamin D Insufficiency in Determining Prognosis in Patients With Newly Diagnosed Follicular Lymphoma

  A completed SWOG trial evaluated whether Vitamin D insufficiency affects prognosis in patients with newly diagnosed Follicular lymphoma.

• CLINICAL_TRIALS trial_result · 2014-04-29
  Clinical Trial Update: MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia [Phase 1]

  Phase 1 study of MK-2206 in pediatric patients with recurrent or refractory solid tumors or leukemias has completed.

• CLINICAL_TRIALS trial_result · 2014-04-21
  Clinical Trial Update: Bortezomib (Velcade) With Standard Chemotherapy for Relapsed or Refractory Follicular Lymphoma [Phase 2]

  This update reports on a Phase 2 trial of bortezomib with standard chemotherapy for relapsed or refractory follicular lymphoma, which was te…

• CLINICAL_TRIALS trial_result · 2014-04-01
  Clinical Trial Update: Bortezomib in Treating Patients With Lymphoproliferative Disorders [Phase 2]

  Phase 2 study of bortezomib in recurrent lymphoproliferative disorders, including follicular lymphoma and mantle cell lymphoma; results were…