Follicular Lymphoma
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: MOLyF : Bone Marrow and Follicular Lymphoma [NA]
This entry reports a recruiting clinical trial named MOLyF addressing follicular lymphoma with bone marrow involvement, sponsored by Rennes …
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: Early Stage Follicular LymphOma and RadioTherapy PLUS Anti-CD20 Antibody [Phase 3]
A Phase 3 trial is evaluating radiotherapy plus an anti-CD20 antibody for early-stage follicular lymphoma (WHO grade 1/2 or 3a). The study i…
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: Radiotherapy Followed by Tiselizumab Combined With RCHOP in Previously Untreated Bulky Follicular Lymphoma [Phase 2]
Phase 2 clinical trial assessing radiotherapy followed by Tiselizumab in combination with RCHOP for previously untreated bulky Follicular Ly…
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: Safety Study of Rituximab (SC) Administered in Participants With CD20+ DLBCL or CD20+ Follicular NHL Grade 1 to 3A [Phase 3]
Results from a Phase 3 safety study of subcutaneous rituximab in CD20-positive diffuse large B-cell lymphoma or CD20-positive follicular lym…
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: Idelalisib+Obinutuzumab in Patients With Relapsed/Refractory Follicular Lymphoma [Phase 2]
A Phase 2 trial evaluating idelalisib in combination with obinutuzumab for relapsed or refractory follicular lymphoma was terminated, and re…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: MIL62 Combined With Lenalidomide Versus Lenalidomide for Patients With Rituximab Refractory Follicular Lymphoma [Phase 3]
A Phase 3 trial evaluating MIL62 in combination with Lenalidomide versus Lenalidomide alone for rituximab-refractory follicular lymphoma is …
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: MIL62 Plus Lenalidomide for Patients With Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma (FL and MZL) [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating MIL62 plus lenalidomide for relapsed/refractory indolent non-Hodgkin's lymphoma (follicular lymphom…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: TLR9 Agonist SD-101, Ibrutinib, and Radiation Therapy in Treating Patients With Relapsed or Refractory Grade 1-3A Follicular Lymphoma [Phase 1, Phase 2]
A Phase 1/2 study evaluating SD-101 (TLR9 agonist) combined with Ibrutinib and radiation therapy in relapsed or refractory follicular lympho…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Study of Mosunetuzumab Plus Lenalidomide Compared to Anti-CD20 Anti-body + Chemotherapy in Follicular Lymphoma FLIPI2-5 [Phase 3]
Phase 3 trial evaluating mosunetuzumab plus lenalidomide versus anti-CD20 antibody plus chemotherapy in follicular lymphoma (FLIPI2-5) is cu…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Zanubrutinib, Obinutuzumab and Lenalidomide (ZGR) in High-risk Treatment-naive Patients with Follicular Lymphoma (FL) [Phase 2]
A Phase 2 trial evaluating a triplet regimen of zanubrutinib, obinutuzumab, and lenalidomide (ZGR) in high-risk, treatment-naive follicular …
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CLINICAL_TRIALS research · 2024-10-09Clinical Trial Update: Study of Tazemetostat in Newly Diagnosed Diffuse Large B Cell and Follicular Lymphoma Patients Treated by Chemiotherapy [Phase 1, Phase 2]
Update on a Phase 1/Phase 2 study of tazemetostat in newly diagnosed diffuse large B-cell lymphoma and follicular lymphoma treated with chem…
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CLINICAL_TRIALS trial_result · 2024-10-04Clinical Trial Update: An Open-Label, Multicenter Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab in Combination With Tiragolumab With or Without Atezolizumab in Participants With B-Cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]
Termination of a Phase 1/2 open-label trial evaluating mosunetuzumab in combination with tiragolumab, with or without atezolizumab, in B-cel…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: Ibrutinib in Combination With Rituximab and Lenalidomide in Treating Patients With Previously Untreated, Stage II-IV Follicular Lymphoma or Marginal Zone Lymphoma [Phase 2]
Phase 2 trial evaluating the combination of ibrutinib with rituximab and lenalidomide in previously untreated stage II-IV follicular lymphom…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: 1630GCC: Zydelig Maintenance in B-Cell Non-Hodgkin's Lymphoma After Autologous Stem Cell Transplantation [Phase 2]
Phase 2 trial evaluating Zydelig (idelalisib) as maintenance therapy after autologous stem cell transplantation in B-cell non-Hodgkin lympho…
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FDA approval · 2024-09-11FDA Approved: LENALIDOMIDE — Original Application (Novugen Pharma (USA) LLC)
FDA approved the original application for lenalidomide from Novugen Pharma (USA) LLC, enabling a generic version of the cancer drug lenalido…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: A Study to Evaluate the Effect of Vitamin D on PFS in Indolent Non-Hodgkin's Lymphoma [Phase 3]
Phase 3 trial evaluating the effect of Vitamin D on progression-free survival in indolent non-Hodgkin lymphoma has completed with results po…
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CLINICAL_TRIALS research · 2024-09-03Clinical Trial Update: Zanubrutinib in Combination With Obinutuzumab (ZO) for Newly Diagnosed Follicular Lymphoma [Phase 2]
Phase 2 study update describing Zanubrutinib in combination with Obinutuzumab for newly diagnosed follicular lymphoma, currently recruiting.
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: ISRT 20 Gy for Indolent Localized Gastrointestinal (GI)-Lymphoma [NA]
Clinical trial update for indolent localized GI lymphomas using 20 Gy involved-site radiotherapy (ISRT); currently recruiting for gastric or…
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels [Phase 1]
Phase 1 trial assessing the pharmacokinetic interactions of itraconazole and rifampin with tazemetostat; results published for patients with…
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: Bendamustine Plus Rituximab Versus CHOP Plus Rituximab [Phase 3]
A Phase 3 trial comparing Bendamustine plus Rituximab vs CHOP plus Rituximab in various non-Hodgkin lymphomas has completed.
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: Optimizing ctDNA-based MRD Assessment in DLBCL, MCL, and FL Patients Undergoing CAR Therapy
This clinical trial update from Adaptive Biotechnologies aims to optimize ctDNA-based minimal residual disease assessment in patients with f…
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: Significance of Duration of Maintenance Therapy With Rituximab in Non-Hodgkin Lymphomas [Phase 3]
This Phase 3 trial update discusses how the duration of rituximab maintenance therapy may affect outcomes in various non-Hodgkin lymphomas, …
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: ENABLE-1 (Engaging Toll-like Receptor Signalling for B-cell Lymphoma Chimeric Antigen Receptor Therapy) [Phase 1]
The ENABLE-1 Phase 1 trial investigates Toll-like receptor signaling to enhance B-cell lymphoma CAR-T therapy, with the study currently list…
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: CLBR001 and SWI019 in Patients With Relapsed / Refractory B-cell Malignancies [Phase 1]
Phase 1 trial update for CLBR001 and SWI019 in relapsed/refractory B-cell malignancies has completed enrollment in a study targeting multipl…
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CLINICAL_TRIALS trial_result · 2024-08-15Clinical Trial Update: Vaccination for the Treatment of Previously Untreated or Relapsed Follicular Lymphoma [Phase 1]
Phase 1 trial evaluating a cancer vaccine for previously untreated or relapsed Follicular Lymphoma has completed.