Focal Epilepsy
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: Home Ultra-long Term EEG Monitoring for Rare Epilepsies and Developmental and Epileptic Encephalopathies [NA]
Clinical trial update for a study evaluating home ultra-long term EEG monitoring for rare epilepsies and developmental and epileptic encepha…
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CLINICAL_TRIALS withdrawal · 2024-12-30Clinical Trial Update: Efficacy of Intersectional Short Pulse Stimulation for Terminating Seizures [NA]
A clinical trial evaluating intersectional short pulse stimulation to terminate seizures has been withdrawn.
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Transcranial Magnetic Stimulation (rTMS) for Refractory Focal Epilepsy [NA]
An update on a clinical trial evaluating repetitive transcranial magnetic stimulation (rTMS) for refractory focal epilepsy. The study is cur…
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CLINICAL_TRIALS trial_result · 2024-09-25Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, and Efficacy of CB03-154 in Adult Patients With Focal Epilepsy [Phase 2]
An ongoing Phase 2 study is evaluating safety, tolerability, and efficacy of CB03-154 in adult patients with focal epilepsy. The trial statu…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy [Phase 2]
Phase 2 study evaluating XEN1101 as adjunctive therapy in focal epilepsy has posted results.
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: Study of Interest of Stiripentol and Carbamazepine in the Treatment of Patients With Pharmacoresistant Focal Epilepsies [Phase 4]
Phase 4 study evaluating the combination of stiripentol and carbamazepine for pharmacoresistant focal epilepsies has completed.
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CLINICAL_TRIALS research · 2024-07-23Clinical Trial Update: Diffusion MRI Methods to Minimize Postoperative Deficits in Pediatric Epilepsy Surgery [NA]
A Wayne State University–sponsored clinical trial is evaluating diffusion MRI techniques to minimize postoperative deficits in pediatric foc…
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CLINICAL_TRIALS research · 2024-06-24Clinical Trial Update: Cognitive Impairment in Drug-resistant and Drug-responsive Focal Cryptogenic Epilepsy
This entry provides a clinical trial update on a study investigating cognitive impairment in patients with drug-resistant and drug-responsiv…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Optimized Volumetry in Radiology: Interest in Pediatric Brain MRI in the Exploration of Focal Epilepsy
A pediatric brain MRI trial using optimized volumetry to explore focal epilepsy, currently recruiting at University Hospital, Tours.
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: The Efficacy and Safety of Lamotrigine Versus Carbamazepine in Focal Epilepsy [Phase 4]
A Phase 4 clinical trial comparing lamotrigine to carbamazepine for efficacy and safety in focal epilepsy. Status is unknown.
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CLINICAL_TRIALS trial_result · 2022-01-31Clinical Trial Update: An Open-label Extension Study of UCB0942 in Adult Patients With Highly Drug-resistant Focal Epilepsy [Phase 2]
Open-label extension study of UCB0942 in adults with highly drug-resistant focal epilepsy has been terminated; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2020-02-18Clinical Trial Update: Efficacy and Safety of Rapid Titration Protocols of Lacosamide [Phase 4]
Phase 4 clinical trial examining efficacy and safety of rapid titration protocols of lacosamide for focal epilepsy has completed.
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CLINICAL_TRIALS trial_result · 2019-02-05Clinical Trial Update: A Study of UCB0942 in Adult Patients With Highly Drug-resistant Focal Epilepsy [Phase 2]
This is a Phase 2 study of UCB0942 in adults with highly drug-resistant focal epilepsy; the trial has completed and results were posted in 2…
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: Study Evaluating Changes in Total Drug Load and Seizure Frequency Using Vimpat® (Lacosamide) in Combination Therapy
A completed clinical trial evaluating changes in total drug load and seizure frequency with Vimpat (lacosamide) in combination therapy for f…
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CLINICAL_TRIALS trial_result · 2016-09-26Clinical Trial Update: Lacosamide IV and EEG/EKG (LIVE) Study [Phase 2]
A Phase 2 clinical trial evaluating intravenous lacosamide with EEG/EKG monitoring was terminated.
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CLINICAL_TRIALS trial_result · 2015-04-13Clinical Trial Update: A Study of Brivaracetam in Subjects With Partial Onset Seizures [Phase 2]
This report covers the completion of a Phase 2 trial evaluating Brivaracetam in subjects with focal epilepsy presenting partial-onset seizur…
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: Arterial Spin Labeling MRI Focal Abnormalities in Refractory Epilepsy [NA]
Results from a completed Mayo Clinic clinical trial assessing arterial spin labeling MRI abnormalities in patients with refractory focal epi…
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CLINICAL_TRIALS trial_result · 2014-12-09Clinical Trial Update: The Effects on Cognitive Function of Levetiracetam (Keppra®) Compared to Carbamazepine (Tegretol®, Carmazepine®) as Monotherapy for Children With Partial Seizure; A Multicentric Randomized Controlled Study [Phase 4]
A multicenter Phase 4 randomized trial comparing cognitive outcomes of levetiracetam versus carbamazepine as monotherapy in children with fo…
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CLINICAL_TRIALS trial_result · 2014-10-13Clinical Trial Update: An Open Label Study of Levetiracetam Monotherapy in Patients With Newly Diagnosed Focal Epilepsy [Phase 3]
Phase 3 open-label study assessing levetiracetam monotherapy in patients with newly diagnosed focal epilepsy.
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CLINICAL_TRIALS trial_result · 2014-06-27Clinical Trial Update: Efficacy and Safety of an add-on Treatment With Zonisamide in Adults With Focal Epileptic Seizures With or Without Secondary Generalization [Phase 4]
Phase 4 trial evaluating add-on zonisamide for adults with focal epilepsy (with or without secondary generalization); the study assessing ef…
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CLINICAL_TRIALS trial_result · 2013-06-21Clinical Trial Update: Thermographic Examination of Skin Temperatures in Individuals With Focal Onset Epilepsy
A completed clinical trial evaluating thermographic assessment of skin temperature patterns in individuals with focal epilepsy.
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CLINICAL_TRIALS trial_result · 2013-02-28Clinical Trial Update: Study on the Treatment of Elderly Patients With Older and Newer Antiepileptic Drugs [Phase 4]
Phase 4 clinical trial in elderly patients comparing older and newer antiepileptic drugs for focal epilepsy has completed and results were p…
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CLINICAL_TRIALS trial_result · 2010-07-23Clinical Trial Update: A Prospective, Observational Study On The Effectiveness Of New Antiepileptic Drugs As First Bitherapy In The Daily Clinical Practice [Phase 4]
Prospective observational Phase 4 trial assessing the effectiveness of new antiepileptic drugs as first adjunct therapy in daily practice fo…