Focal Epilepsy
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy [Phase 2, Phase 3]
Biohaven is conducting a Phase 2/3 trial to assess the safety and efficacy of BHV-7000 in adults with refractory focal onset epilepsy. The s…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Long-term Safety and Tolerability of BHV-7000 [Phase 2]
This clinical trial update describes the ongoing Phase 2 assessment of BHV-7000 for focal epilepsy, focusing on long-term safety and tolerab…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies
This ClinicalTrials.gov update outlines a genetic and electrophysiologic study investigating drug-resistant focal epilepsies in pediatric pa…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: An Open-label Study of XEN1101 in Epilepsy [Phase 3]
An open-label Phase 3 study evaluating XEN1101 for epilepsy is underway, with enrollment by invitation.
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Investigating Epilepsy: Screening and Evaluation
A ClinicalTrials.gov entry shows that the NINDS-sponsored study on epilepsy screening and evaluation is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Double-blind, Randomized Clinical Trial Evaluating the Efficacy and Safety of Vormatrigine in Adults With Focal Seizures [Phase 3]
This document notes a Phase 3 double-blind, randomized trial evaluating the efficacy and safety of Vormatrigine in adults with focal epileps…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy [Phase 2, Phase 3]
This is a Phase 2/3 clinical trial evaluating BHV-7000 for safety and efficacy in adults with refractory focal onset epilepsy; recruitment i…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Optimizing Therapy in Epilepsy Using Seizure Forecasts Via EEG and Wearables [NA]
Clinical trial update from Mayo Clinic exploring seizure forecasting with EEG and wearables to optimize epilepsy therapy; the study is curre…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Thalamic Recordings in Children Undergoing SEEG [NA]
This clinical trial update describes thalamic recordings in children undergoing SEEG for focal epilepsy; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Study of Transcranial Direct Current Stimulation to Treat Epilepsy [NA]
This document reports an ongoing clinical trial evaluating transcranial direct current stimulation as a treatment for epilepsy; the study is…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures [Phase 2]
A Phase 2 long-term study of RAP-219 for safety and effectiveness in adults with focal onset seizures is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Efficacy of Probenecid on Cluster Seizures During Anti Seizure Medication Withdrawal in Presurgical Focal Epilepsy Video-EEG Monitoring [Phase 2]
A Phase 2 clinical trial evaluating the efficacy of probenecid on cluster seizures during withdrawal of anti-seizure medications in presurgi…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Impact of Epileptic Discharge on the Structural Connectivity of the Developing Brain
A clinical trial entry describes a study on how epileptic discharges affect structural connectivity in the developing brain. The study targe…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Evaluation of New Flexible High-density Intra-operative ECoG Electrodes for Epilepsy Surgery. ( EpiGrid ) [NA]
Update on a clinical trial evaluating flexible high-density intraoperative ECoG electrodes (EpiGrid) for epilepsy surgery; the study is curr…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: An Open-label Study to Evaluate Safety, Tolerability, and Efficacy of CB03-154 in Subjects Diagnosed With Epilepsy [Phase 2]
An open-label Phase 2 clinical trial to evaluate the safety, tolerability, and efficacy of CB03-154 in subjects with focal epilepsy, current…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Butylphthalide for Cognitive Impairment in Elderly Patients With Focal Epilepsy [Phase 4]
Phase 4 clinical trial evaluating the use of Butylphthalide for cognitive impairment in elderly patients with focal epilepsy is currently re…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Real-world Clinical Response to Cenobamate Early add-on in France, Germany and Spain
This document reports a clinical trial investigating cenobamate as an early add-on therapy for focal epilepsy across France, Germany, and Sp…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Multi-level Approach of Brain Activity Using Intracranial Electrodes in Epileptic Patients [NA]
This entry reports a clinical trial investigating multi-level brain activity using implanted intracranial electrodes in patients with epilep…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Sleep Architecture & Cognition in Focal Epilepsy [NA]
This clinical trial update notes that the University of California, Davis is recruiting for a study on sleep architecture and cognition in i…
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Breathing Rescue for SUDEP Prevention [NA]
A ClinicalTrials.gov update indicates a trial titled 'Breathing Rescue for SUDEP Prevention' sponsored by The University of Texas Health Sci…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: Home Ultra-long Term EEG Monitoring for Rare Epilepsies and Developmental and Epileptic Encephalopathies [NA]
Clinical trial update for a study evaluating home ultra-long term EEG monitoring for rare epilepsies and developmental and epileptic encepha…
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Transcranial Magnetic Stimulation (rTMS) for Refractory Focal Epilepsy [NA]
An update on a clinical trial evaluating repetitive transcranial magnetic stimulation (rTMS) for refractory focal epilepsy. The study is cur…
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CLINICAL_TRIALS research · 2024-07-23Clinical Trial Update: Diffusion MRI Methods to Minimize Postoperative Deficits in Pediatric Epilepsy Surgery [NA]
A Wayne State University–sponsored clinical trial is evaluating diffusion MRI techniques to minimize postoperative deficits in pediatric foc…
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CLINICAL_TRIALS research · 2024-06-24Clinical Trial Update: Cognitive Impairment in Drug-resistant and Drug-responsive Focal Cryptogenic Epilepsy
This entry provides a clinical trial update on a study investigating cognitive impairment in patients with drug-resistant and drug-responsiv…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Optimized Volumetry in Radiology: Interest in Pediatric Brain MRI in the Exploration of Focal Epilepsy
A pediatric brain MRI trial using optimized volumetry to explore focal epilepsy, currently recruiting at University Hospital, Tours.