Focal Cortical Dysplasia
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Astroscape: A Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients With TSC or FCD Type II [Phase 1, Phase 2]
This clinical trial update describes Radiprodil in Phase 1/2 studies evaluating safety, tolerability, pharmacokinetics, and its effect on se…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics of SVG103 (Paxalisib) in Focal Cortical Dysplasia Type II (FCD-II), Tuberous Sclerosis Complex (TSC) or Hemimegalencephaly (HME) [Phase 1, Phase 2]
Clinical trial update on SVG103 (paxalisib) evaluating safety, tolerability, and pharmacokinetics in focal cortical dysplasia type II, tuber…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Study to Evaluate the Pharmacokinetics and Safety Effects Following Coadministration of Carbamazepine or Itraconazole With Radiprodil in Healthy Adults [Phase 1]
Phase 1 study evaluating pharmacokinetics and safety of coadministering Radiprodil with Carbamazepine or Itraconazole in healthy adults; the…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Phase 1, Open-label, Drug-drug Interaction Study to Assess Effect Between Radiprodil and the Co-administered Drugs. [Phase 1]
Phase 1 open-label drug-drug interaction study of Radiprodil in the treatment of Tuberous Sclerosis Complex and Focal Cortical Dysplasia has…
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CLINICAL_TRIALS research · 2024-10-23Clinical Trial Update: Mos-FED (Mosaicism in Focal Epilepsy Cortical Dysplasia Tissue) [NA]
This document notes a clinical trial update for Mos-FED studying mosaicism in focal epilepsy cortical dysplasia tissue. The study is current…
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CLINICAL_TRIALS trial_result · 2021-09-01Clinical Trial Update: A Pilot Study To Evaluate The Effects of Everolimus on Brain mTOR Activity and Cortical Hyperexcitability in TSC and FCD [Phase 2]
Phase 2 pilot study evaluating everolimus on brain mTOR activity and cortical hyperexcitability in epilepsy related to tuberous sclerosis co…
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CLINICAL_TRIALS trial_result · 2013-09-05Clinical Trial Update: Determining the Extent of Diffusion Tensor Abnormalities in Focal Cortical Dysplasia
The trial has completed an assessment of diffusion tensor imaging abnormalities in focal cortical dysplasia, in the context of epilepsy.