Fatty Liver Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Single-Cell and Spatial Transcriptomics Analysis of Steatotic Donor Liver Susceptibility to Post-Transplant Injury
This completed clinical trial analyzed single-cell and spatial transcriptomics to investigate how steatotic donor livers are susceptible to …
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Effect of Lifestyle Intervention on Mobilization of Fat Storage and Iron Deposition in Obesity [NA]
This clinical trial update notes the completion of a study evaluating whether lifestyle intervention can mobilize fat storage and iron depos…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Gepaktiv vs UDCA and Ademetionine in MAFLD With Hepatomegaly [NA]
A clinical study comparing Gepaktiv to ursodeoxycholic acid (UDCA) and ademetionine in metabolic dysfunction-associated fatty liver disease …
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CLINICAL_TRIALS withdrawal · 2025-06-05Clinical Trial Update: A Pilot Study to Explore the Role of Gut Flora in Fatty Liver
A pilot trial exploring the role of gut microbiota in fatty liver has been withdrawn. The study identifier is NCT04160949 and sponsor is Pro…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Ultrasound Assessment of Atherosclerotic Plaque Burden and Cardiovascular Risk: A 10-Year Prospective Study
This clinical trial update reports results from a 10-year prospective study using ultrasound to assess atherosclerotic plaque burden and its…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Effect of Fatty Liver on TCA Cycle Flux and the Pentose Phosphate Pathway
A completed UT Southwestern clinical trial examined how fatty liver affects mitochondrial TCA cycle flux and the pentose phosphate pathway.
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Metabolic Changes in Healthy Subjects with Acute Binge Drink [Phase 1]
Phase 1 clinical trial investigating metabolic changes in healthy subjects following acute binge drinking. The study has been completed.
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: The Role of Sugars in Fat Accumulation in the Liver [NA]
This entry notes a recruiting clinical trial examining how sugars contribute to fat accumulation in the liver for fatty liver disease, spons…
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: Assessment of FibbroScan in Diagnosing MASLD Among the Chinese Population With Obesity
An ongoing clinical study assessing the use of FibroScan to diagnose metabolic dysfunction-associated steatotic liver disease (MASLD) in obe…
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: Metabolic Associated Fatty Liver Disease in Patients With Chronic Glomerular Disease
This is a clinical trial update for NCT06691529 studying Metabolic Associated Fatty Liver Disease in patients with chronic glomerular diseas…
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CLINICAL_TRIALS research · 2024-10-08Clinical Trial Update: Burden Fatty Liver Among Acute Ischemic Cerebral Stroke Patients
A trial at Assiut University is studying fatty liver in patients with acute ischemic stroke; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Monitoring Changes in Hepatic Steatosis Using Continuous Controlled Attenuation Parameter [NA]
A Chinese University of Hong Kong study is monitoring changes in hepatic steatosis using the Continuous Controlled Attenuation Parameter (CA…
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: Quantification of Hepatic Steatosis With Different Ultrasound Frequency
This clinical trial update describes a study on quantifying hepatic steatosis using ultrasound at different frequencies; the trial is curren…
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CLINICAL_TRIALS research · 2024-07-23Clinical Trial Update: Perirenal Fats of Chronic Kidney Disease in Patients With Fatty Liver Disease.
Assiut University is sponsoring a clinical trial on perirenal fats in patients with chronic kidney disease and fatty liver disease, which is…
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CLINICAL_TRIALS trial_result · 2024-03-13Clinical Trial Update: Effects of Testosterone Undecanoate vs Placebo on Intrahepatic Fat Content in Overweight/Obese Men With T2DM or Prediabetes and Hypogonadism [Phase 4]
Phase 4 clinical trial evaluating testosterone undecanoate versus placebo on intrahepatic fat content in overweight/obese men with type 2 di…
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CLINICAL_TRIALS trial_result · 2023-10-31Clinical Trial Update: Potential Benefits of Itopride in the Management of Patients With Metabolic Associated Fatty Liver Disease (MAFLD) [Phase 2]
Phase 2 clinical trial investigating the potential benefits of itopride for metabolic-associated fatty liver disease (MAFLD).
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CLINICAL_TRIALS trial_result · 2022-09-27Clinical Trial Update: Effect of Probiotics in Non-alcoholic Fatty Liver Disease and Steatohepatitis [Phase 1, Phase 2]
A terminated Phase 1/2 clinical trial evaluating probiotics for non-alcoholic fatty liver disease and steatohepatitis; results have been pos…
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CLINICAL_TRIALS trial_result · 2022-06-30Clinical Trial Update: An Evaluation of the Safety and Efficacy of Nitazoxanide on Collagen Turnover in NASH Patients With Fibrosis [Phase 2]
Phase 2 trial evaluating nitazoxanide for safety and efficacy in reducing collagen turnover in NASH patients with fibrosis; study completed …
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EMA withdrawal · 2022-04-08EMA Application withdrawn: Zektayos - Hepjuvo (obeticholic acid) — Advanz Pharma Limited
The EMA has withdrawn the application for Zektayos - Hepjuvo (obeticholic acid) by Advanz Pharma Limited for fatty liver disease.
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CLINICAL_TRIALS trial_result · 2022-04-01Clinical Trial Update: A Single Center, Randomized, Open Label, Parallel Group, Phase 3 Study to Evaluate the Efficacy of Dapagliflozin in Subjects With Nonalcoholic Fatty Liver Disease [Phase 3]
Phase 3 randomized trial evaluating dapagliflozin in fatty liver disease; status is unknown.
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CLINICAL_TRIALS trial_result · 2021-06-01Clinical Trial Update: Study to Evaluate MET409 Alone or in Combination With Empagliflozin in Patients With Type 2 Diabetes and NASH [Phase 2]
Phase 2 trial evaluating MET409 alone or with empagliflozin in patients with type 2 diabetes and nonalcoholic steatohepatitis (NASH).
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CLINICAL_TRIALS trial_result · 2021-03-24Clinical Trial Update: A Study of Siliphos in Adults With Non-alcoholic Steatohepatitis (NASH) [Phase 2]
Phase 2 clinical trial of Siliphos in adults with fatty liver (NASH) completed; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2020-10-19Clinical Trial Update: Treatment for Non-Alcoholic Fatty Liver With Different Doses of Vitamin E [Phase 2]
Phase 2 trial evaluating different doses of vitamin E for treatment of fatty liver disease has completed with results posted.
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CLINICAL_TRIALS research · 2020-09-14Clinical Trial Update: GSP as an Novel Indicator for Residual Liver Function in Patients With Fatty Liver [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating Galactose Single Point (GSP) as a novel indicator of residual liver function in patients with fatty li…
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CLINICAL_TRIALS trial_result · 2020-06-22Clinical Trial Update: Liver Positron Emission Tomography (PET) Study of Non Alcoholic Fatty Liver Disease [EARLY_Phase 1]
Early-phase liver PET study on non-alcoholic fatty liver disease has completed with results posted.