Familial Partial Lipodystrophy

• CLINICAL_TRIALS trial_result · 2026-03-12
  Clinical Trial Update: Feasibility of Adipose Tissue Triglyceride (TG) Labelling in Familial Partial Lipodystrophy (FPLD)

  This clinical trial update describes a feasibility study evaluating labeling of adipose tissue triglycerides in familial partial lipodystrop…

• CLINICAL_TRIALS trial_result · 2025-07-31
  Clinical Trial Update: The Benefits of the Measureof Epicardial Adipose Tissue During Coronary Calcium Assessment of the Refine Cardiovascular Risk Assessment at Reunion Island.

  This completed clinical study evaluated whether measuring epicardial adipose tissue alongside coronary calcium scoring improves refinement o…

• CLINICAL_TRIALS trial_result · 2025-07-02
  Clinical Trial Update: A Study to Examine the Effects of the Leptin Receptor (LEPR) Agonist Antibody REGN4461 in Adult Patients With Familial Partial Lipodystrophy (FPLD) [Phase 2]

  A Phase 2 study evaluating REGN4461, a leptin receptor agonist antibody, for familial partial lipodystrophy was terminated with results post…

• CLINICAL_TRIALS trial_result · 2023-12-13
  Clinical Trial Update: Phase 2 Study of Obeticholic Acid for Lipodystrophy Patients [Phase 2]

  A Phase 2 trial evaluating obeticholic acid for Familial Partial Lipodystrophy has completed. Results were posted in December 2023.

• CLINICAL_TRIALS trial_result · 2021-10-18
  Clinical Trial Update: The BROADEN Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Partial Lipodystrophy [Phase 2, Phase 3]

  A multi-phase study (Phase 2/3) of volanesorsen in familial partial lipodystrophy was terminated; results were posted in 2021.

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• CLINICAL_TRIALS trial_result · 2021-02-16
  Clinical Trial Update: Study of AKCEA-ANGPTL3-LRx (ISIS 703802) in Participants With Familial Partial Lipodystrophy (FPL) [Phase 2]

  Phase 2 study of AKCEA-ANGPTL3-LRx (ISIS 703802) in familial partial lipodystrophy has completed with posted results.

• CLINICAL_TRIALS trial_result · 2020-11-24
  Clinical Trial Update: CLINICAL PROTOCOL to Investigate the Long-term Safety and Efficacy of Metreleptin in Various Forms of Partial Lipodystrophy [Phase 2]

  Phase 2 clinical protocol update assessing long-term safety and efficacy of metreleptin in various forms of partial lipodystrophy; study sta…

• CLINICAL_TRIALS trial_result · 2020-08-17
  Clinical Trial Update: Study of Gemcabene in Adults With FPLD [Phase 1, Phase 2]

  Phase 1/2 trial updates for gemcabene in adults with familial partial lipodystrophy (FPLD) and hypertriglyceridemia have been completed with…