Familial Adenomatous Polyposis
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CLINICAL_TRIALS trial_result · 2025-01-31Clinical Trial Update: Safety Study for the Use of Rapamycin in Children With Familial Adenomatous Polyposis [Phase 2]
This clinical trial update describes a Phase 2 safety study of rapamycin in children with familial adenomatous polyposis, which is currently…
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CLINICAL_TRIALS research · 2025-01-30Clinical Trial Update: Microbial and Environmental Factors Associated with Polyps Development in Familial Adenomatous Polyposis (MicrobEnvironment in FAP)
A clinical study evaluating how microbial and environmental factors relate to polyp development in individuals with familial adenomatous pol…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Trial of ERapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance [Phase 2]
Phase 2 trial update for ERapa to prevent progression in patients with familial adenomatous polyposis; trial status is active but not recrui…
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Sirolimus and Familial Adenomatous Polyposis (FAP) [Phase 2]
Phase 2 trial evaluating sirolimus for familial adenomatous polyposis (FAP) has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-10-04Clinical Trial Update: The CHAMP-study: The CHemopreventive Effect of Lithium in Familial AdenoMatous Polyposis [Phase 2]
Phase 2 trial investigating the chemopreventive effect of lithium in familial adenomatous polyposis has completed.
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Chemopreventive Effect of Combination of Celecoxib and Metformin in Patients With Familial Adenomatous Polyposis [Phase 3]
Phase 3 trial evaluating the chemopreventive effect of combining celecoxib and metformin in familial adenomatous polyposis is currently recr…
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CLINICAL_TRIALS other · 2024-05-30Clinical Trial Update: Cold Atmospheric Plasma for the Endoscopic Treatment of Duodenal Polyps in Patients With Familial Adenomatous Polyposis [NA]
A clinical trial evaluating cold atmospheric plasma for endoscopic treatment of duodenal polyps in patients with familial adenomatous polypo…
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CLINICAL_TRIALS research · 2024-04-25Clinical Trial Update: Effect of EPA-FFA on Polypectomy in Familial Adenomatous Polyposis [Phase 3]
Phase 3 trial assessing the effect of EPA-FFA on polypectomy in Familial Adenomatous Polyposis; the study is currently active but not recrui…
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CLINICAL_TRIALS trial_result · 2023-02-13Clinical Trial Update: Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers [Phase 2]
Phase 2 trial investigating molecular targeting of 15-LOX-1 to induce apoptosis in colorectal cancers associated with familial adenomatous p…
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CLINICAL_TRIALS trial_result · 2022-07-27Clinical Trial Update: Primary Chemoprevention of Familial Adenomatous Polyposis With Berberine Hydrochloride [Phase 2, Phase 3]
Phase 2/3 trial update on berberine hydrochloride for primary chemoprevention in individuals with familial adenomatous polyposis.
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FDA approval · 2022-03-09FDA Approved: CELECOXIB — Supplemental Application (Micro Labs Limited)
FDA approved a supplemental application for Celecoxib from Micro Labs Limited under an ANDA.
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CLINICAL_TRIALS trial_result · 2021-09-22Clinical Trial Update: Erlotinib Hydrochloride in Reducing Duodenal Polyp Burden in Patients With Familial Adenomatous Polyposis at Risk of Developing Colon Cancer [Phase 2]
Phase 2 trial evaluating erlotinib hydrochloride to reduce duodenal polyp burden in patients with familial adenomatous polyposis at risk of …
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CLINICAL_TRIALS trial_result · 2021-09-20Clinical Trial Update: The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study [Phase 2]
A Phase 2 double-blinded randomized controlled trial evaluating the chemopreventive effect of metformin in patients with familial adenomatou…
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CLINICAL_TRIALS trial_result · 2021-06-08Clinical Trial Update: Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP) [Phase 3]
Phase 3 trial of eflornithine plus sulindac for familial adenomatous polyposis completed with results posted.
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CLINICAL_TRIALS research · 2020-12-16Clinical Trial Update: Use of Curcumin for Treatment of Intestinal Adenomas in Familial Adenomatous Polyposis (FAP) [NA]
Clinical trial update on curcumin for treating intestinal adenomas in familial adenomatous polyposis (FAP); status completed with results po…
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CLINICAL_TRIALS trial_result · 2020-07-01Clinical Trial Update: Azithromycin Treatment for Readthrough of APC Gene Stop Codon Mutations in Familial Adenomatous Polyposis [Phase 4]
Phase 4 trial investigating azithromycin to promote readthrough of APC stop codon mutations in familial adenomatous polyposis.
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CLINICAL_TRIALS trial_result · 2020-03-05Clinical Trial Update: Niclosamide for Familial Adenomatous Polyposis [Phase 2]
Phase 2 trial update for niclosamide in familial adenomatous polyposis (FAP) is reported with unknown status.
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CLINICAL_TRIALS research · 2018-02-28Clinical Trial Update: French Digestive Polyposis Cohorte Family Adenomatous Polyposis With APC and MYH Gene Mutations , Cowden's Disease With PTEN Gene Mutation, Peutz Jeghers Disease With STK 11 Gene Mutation ,juvénil Polyposis With SMAD 4 Gene Mutation , Serrated and Hyperplastic Polyposis
This clinical trial update from Hôpital Edouard Herriot describes a French cohort of patients with several hereditary polyposis syndromes (f…
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CLINICAL_TRIALS trial_result · 2017-12-06Clinical Trial Update: Single Incision Laparoscopic Surgery in Treating Patients With Colorectal Disease [NA]
Completed clinical trial evaluating single incision laparoscopic surgery for colorectal disease, including adenomatous polyp, Crohn's diseas…
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CLINICAL_TRIALS trial_result · 2017-09-29Clinical Trial Update: Curcumin in Treating Patients With Familial Adenomatous Polyposis [Phase 2]
Phase 2 trial evaluating curcumin for Familial Adenomatous Polyposis has completed; results posted in 2017.
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CLINICAL_TRIALS research · 2017-02-23Clinical Trial Update: Turmeric Supplementation on Polyp Number and Size in Patients With Familial Adenomatous Polyposis. [Phase 2]
A Phase 2 clinical trial is evaluating turmeric supplementation for effects on polyp number and size in patients with familial adenomatous p…
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CLINICAL_TRIALS trial_result · 2016-09-27Clinical Trial Update: Non-Invasive Prediction of Colorectal Neoplasia
This update reports that the clinical trial on non-invasive prediction of colorectal neoplasia has been terminated.
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CLINICAL_TRIALS trial_result · 2016-06-17Clinical Trial Update: A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients [Phase 2]
Phase 2 trial evaluating COX and EGFR inhibition in familial adenomatous polyposis; the study has been completed and results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-02-15Clinical Trial Update: Lyophilized Black Raspberries in Adults With Familial Adenomatous Polyposis (FAP) [Phase 1]
Phase 1 clinical trial update evaluating lyophilized black raspberries in adults with Familial Adenomatous Polyposis; the study has complete…
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CLINICAL_TRIALS research · 2016-01-14Clinical Trial Update: Small Bowel Endoscopic Evaluation in Familial Adenomatous Polyposis (FAP)
Clinical trial update describing a study on small bowel endoscopic evaluation in Familial Adenomatous Polyposis. The trial status is current…