Extrahepatic Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial) [Phase 2]
Phase 2 clinical trial evaluating chemotherapy with or without binimetinib for advanced biliary tract cancers. The study is currently active…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Repeated Endobiliary Radiofrequency Ablation Plus Durvalumab, Gemcitabine, and Cisplatin for Unresectable Extrahepatic Cholangiocarcinoma [NA]
Clinical trial update for a study evaluating repeated endobiliary radiofrequency ablation in combination with durvalumab, gemcitabine, and c…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Durvalumab + Intraductal Radiofrequency Ablation (ID-RFA) in Extrahepatic Cholangiocarcinoma [Phase 2]
Phase 2 clinical trial evaluating durvalumab in combination with intraductal radiofrequency ablation for unresectable extrahepatic cholangio…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Taxoprexin® Treatment for Advanced Primary Cancers of the Liver, Gallbladder or Biliary Tract [Phase 2]
Phase 2 trial of Taxoprexin for advanced primary cancers of the liver, gallbladder, or biliary tract was terminated.
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Nal-IRI With 5-fluorouracil (5-FU) and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Biliary-tract Cancer [Phase 2]
This clinical trial update notes the completion of a phase 2 study evaluating nanoliposomal irinotecan (nal-IRI) with either 5-fluorouracil/…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: A Cell-free DNA Methylation Blood-Based Test for Biliary Tract Cancers Screening
This clinical trial is evaluating a cell-free DNA methylation blood test for screening biliary tract cancers and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: Feasibility Study of Multi-Platform Profiling of Resected Biliary Tract Cancer
This clinical trial update reports the termination of a feasibility study evaluating multi-platform profiling of resected biliary tract canc…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Validation of the Proteomic Profiling as a Diagnostic Test for Extra-hepatic Cholangiocarcinoma
A not-yet-recruiting clinical trial to validate a proteomic profiling-based diagnostic test for extrahepatic cholangiocarcinoma.
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: Intraductal Radiofrequency Thermoablation and Radiotherapy Combined Treatment for Extrahepatic Cholangiocarcinoma [NA]
A National Cancer Center, Korea trial is recruiting to assess intraductal radiofrequency thermoablation combined with radiotherapy for extra…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Bile Omics for Diagnosing Indeterminate Biliary Strictures
A recruiting study evaluating Bile Omics as a diagnostic tool for indeterminate biliary strictures to improve detection of biliary cancers a…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Adjuvant Immunotherapy Combined With ChemoRadiation for Patients With High-risk Resectable Extrahepatic Cholangiocarcinoma(AICRC)
This document provides an update on a clinical trial evaluating adjuvant immunotherapy in combination with chemoradiation for high-risk, res…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Neoadjuvant Gemcitabine and Cisplatin in Combination With Perioperative Pembrolizumab Versus Upfront Surgery for Patients With Primary Resectable and Borderline Resectable Perihilar and Distal Cholangiocarcinoma [Phase 2, Phase 3]
A Phase 2/3 clinical trial compares neoadjuvant gemcitabine and cisplatin with perioperative pembrolizumab versus upfront surgery in patient…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Camrelizumab and Chemotherapy With or Without Anlotinib as First-line Treatment for Advanced Gallbladder Cancer and Extrahepatic Cholangiocarcinoma [Phase 2]
The document outlines a Phase 2 clinical trial evaluating first-line therapy with camrelizumab and chemotherapy, with or without anlotinib, …
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CLINICAL_TRIALS trial_result · 2025-03-18Clinical Trial Update: Expanded Access for the Treatment of Advanced Cholangiocarcinoma With ABC294640 (Yeliva ®)
Expanded Access for ABC294640 (Yeliva) in advanced cholangiocarcinoma has been closed and is no longer available.
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Safety of Biliary Intraductal Radiofrequency Ablation in Patients With Unresectable Extrahepatic Biliary Tract Cancer [Phase 2]
A Phase 2 clinical trial update evaluating the safety of biliary intraductal radiofrequency ablation in patients with unresectable extrahepa…
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CLINICAL_TRIALS research · 2025-01-06Clinical Trial Update: Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG) [NA]
The LIVELONG trial from University of California, Davis is an ongoing study evaluating locally ablative therapy for oligoprogressive gastroi…
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: Study of Irinotecan Liposome Injection in Patients With Advanced Biliary Tract Cancer [Phase 2]
A Phase 2 study of irinotecan liposome injection in patients with advanced biliary tract cancer has been terminated.
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CLINICAL_TRIALS trial_result · 2023-04-21Clinical Trial Update: Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer [NA]
Clinical trial update for M5A, a Copper-64 labeled anti-CEA monoclonal antibody used in PET imaging to diagnose CEA-positive cancers; the st…
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CLINICAL_TRIALS trial_result · 2022-07-07Clinical Trial Update: An Observational Real World Study on the Efficacy and Safety of Toripalimab Injection Combined With TACE in the Treatment of Extrahepatic Cholangiocarcinoma [Phase 2]
Observational real-world Phase 2 study evaluating toripalimab plus TACE for extrahepatic cholangiocarcinoma.
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CLINICAL_TRIALS trial_result · 2020-06-23Clinical Trial Update: Adjuvant Immunotherapy Combined With Chemoradiation for Patients With High-risk reseCtable Extrahepatic chOlangiocaRcinoma and gallblaDder Cancer [Phase 2]
A Phase 2 clinical trial evaluating adjuvant immunotherapy in combination with chemoradiation for high-risk resectable biliary tract cancers…
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CLINICAL_TRIALS trial_result · 2019-02-28Clinical Trial Update: Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers [Phase 3]
Phase 3 trial evaluating early palliative care added to standard care versus standard care alone in patients with incurable lung or non-colo…
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CLINICAL_TRIALS trial_result · 2018-05-07Clinical Trial Update: Molecularly Target Therapy With GEMOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma [Phase 2]
This report covers a Phase 2 trial of GEMOX (gemcitabine plus oxaliplatin) for advanced or recurrent extrahepatic cholangiocarcinoma and gal…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Bortezomib in Treating Patients With Unresectable Locally Advanced or Metastatic Adenocarcinoma of the Bile Duct or Gallbladder [Phase 2]
Phase 2 trial evaluating Bortezomib in unresectable or metastatic adenocarcinoma of the bile duct or gallbladder was terminated; results wer…
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CLINICAL_TRIALS trial_result · 2017-05-16Clinical Trial Update: MRCP Diagnoses EHCC Better When Combined DWI [NA]
A completed clinical trial indicates that using MRCP in combination with diffusion-weighted imaging improves the diagnostic accuracy for ext…
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Combination Chemotherapy in Treating Patients With Unresectable or Metastatic Biliary Tract or Gallbladder Cancer [Phase 2]
Phase 2 clinical trial evaluating combination chemotherapy in unresectable or metastatic biliary tract and gallbladder cancer has completed.