Extragonadal Germ Cell Tumor

• CLINICAL_TRIALS trial_result · 2025-03-20
  Clinical Trial Update: Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor [Phase 1]

  Phase 1 trial evaluating a conditioning regimen of busulfan, melphalan, and topotecan hydrochloride followed by stem cell transplantation in…

• CLINICAL_TRIALS trial_result · 2022-04-27
  Clinical Trial Update: Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors [Phase 1, Phase 2]

  Phase 1/Phase 2 trial investigating dasatinib combined with ifosfamide, carboplatin, and etoposide in young patients with metastatic or recu…

• CLINICAL_TRIALS trial_result · 2021-06-07
  Clinical Trial Update: Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors [Phase 3]

  Phase 3 trial evaluating combination chemotherapy for stage II or stage III germ cell tumors has completed enrollment and posted results. Th…

• CLINICAL_TRIALS trial_result · 2021-03-11
  Clinical Trial Update: Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer [Phase 2]

  Phase II trial of the CDK inhibitor PD 0332991 (palbociclib) in various adult solid tumors including colon and breast cancers has completed …

• CLINICAL_TRIALS trial_result · 2021-02-23
  Clinical Trial Update: Combination Chemotherapy With Bone Marrow Transplantation in Treating Men With Germ Cell Tumors [Phase 3]

  Phase 3 trial evaluating combination chemotherapy with bone marrow transplantation for germ cell tumors has completed recruitment.

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• CLINICAL_TRIALS trial_result · 2018-08-10
  Clinical Trial Update: Carboplatin, Etoposide, Cyclophosphamide, and Autologous Bone Marrow Transplantation in Patients With Relapsed or Refractory Cancer [Phase 2]

  Phase 2 trial evaluating a regimen of carboplatin, etoposide, cyclophosphamide, and autologous bone marrow transplant in relapsed or refract…

• CLINICAL_TRIALS trial_result · 2017-10-24
  Clinical Trial Update: Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors [Phase 2]

  Phase 2 trial of combination chemotherapy with pegfilgrastim in previously untreated germ cell tumors has completed, with results posted.

• CLINICAL_TRIALS trial_result · 2017-06-01
  Clinical Trial Update: Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy [Phase 3]

  Phase 3 trial evaluating sodium thiosulfate to prevent cisplatin-induced hearing loss in young patients with various pediatric cancers; stud…

• CLINICAL_TRIALS trial_result · 2017-01-04
  Clinical Trial Update: Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer [Phase 2]

  Phase 2 trial evaluating combination chemotherapy plus peripheral stem cell transplantation for relapsed germ cell cancer; results have been…

• CLINICAL_TRIALS trial_result · 2016-07-04
  Clinical Trial Update: Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors [Phase 3]

  A Phase 3 trial evaluating cisplatin and ifosfamide with either paclitaxel or vinblastine for progressive or recurrent metastatic germ cell …

• CLINICAL_TRIALS trial_result · 2016-06-23
  Clinical Trial Update: Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Germ Cell Tumors [Phase 2]

  Phase 2 trial evaluating combination chemotherapy with peripheral stem cell transplantation for germ cell tumors has been terminated.

• CLINICAL_TRIALS trial_result · 2016-05-23
  Clinical Trial Update: Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Germ Cell Tumors [Phase 1, Phase 2]

  This clinical trial update reports on the results of combining chemotherapy with peripheral stem cell transplantation in patients with germ …

• CLINICAL_TRIALS trial_result · 2016-05-18
  Clinical Trial Update: Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin [Phase 1, Phase 2]

  Phase 1/2 trial evaluating paclitaxel, ifosfamide, and carboplatin followed by autologous stem cell transplant in patients with cisplatin-re…

• CLINICAL_TRIALS trial_result · 2015-11-25
  Clinical Trial Update: Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors [Phase 2]

  Arsenic trioxide was studied in a Phase 2 trial for children with advanced neuroblastoma and other childhood solid tumors; results have been…

• CLINICAL_TRIALS trial_result · 2015-10-27
  Clinical Trial Update: Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment [Phase 2]

  Phase 2 trial evaluating sunitinib for metastatic germ cell tumors that relapsed or were refractory to prior treatment; the study completed …

• CLINICAL_TRIALS trial_result · 2015-07-02
  Clinical Trial Update: Palifosfamide in Treating Patients With Recurrent Germ Cell Tumors [Phase 2]

  Phase 2 trial of palifosfamide for recurrent germ cell tumors was terminated; results were posted in 2015.

• CLINICAL_TRIALS trial_result · 2013-10-17
  Clinical Trial Update: Combination Chemotherapy in Treating Children With Newly Diagnosed Malignant Germ Cell Tumors [NA]

  A completed clinical trial evaluating combination chemotherapy for children with newly diagnosed malignant germ cell tumors, including extra…

• CLINICAL_TRIALS trial_result · 2013-09-17
  Clinical Trial Update: Observation and/or Combination Chemotherapy After Surgery or Biopsy in Treating Young Patients With Extracranial Germ Cell Tumors [Phase 3]

  Phase 3 clinical trial evaluating observation and/or combination chemotherapy after surgery or biopsy in young patients with extracranial ge…

• CLINICAL_TRIALS trial_result · 2013-08-26
  Clinical Trial Update: Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors [Phase 2]

  Phase 2 clinical trial evaluating combination chemotherapy in male patients with germ cell tumors has completed.

• CLINICAL_TRIALS trial_result · 2013-08-12
  Clinical Trial Update: High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to First-Line Therapy [Phase 2]

  A Phase 2 clinical trial is evaluating high-dose chemotherapy with stem cell transplantation for metastatic germ cell tumors that did not re…

• CLINICAL_TRIALS trial_result · 2013-08-12
  Clinical Trial Update: Treatment Outcome and Quality of Life in Patients With Pediatric Extra-Cranial Germ Cell Tumors Previously Treated on Clinical Trial CCLG-GC-1979-01 or CCLG-GC-1989-01

  A clinical trial update assessing treatment outcomes and quality of life in pediatric patients with extracranial germ cell tumors who had pr…

• CLINICAL_TRIALS trial_result · 2013-08-07
  Clinical Trial Update: Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors [Phase 2]

  Phase 2 trial evaluating a combination chemotherapy regimen with pegfilgrastim in men with metastatic germ cell tumors has completed.

• CLINICAL_TRIALS trial_result · 2013-08-02
  Clinical Trial Update: Levofloxacin to Prevent Infection Following Chemotherapy in Treating Patients With Solid Tumors or Lymphoma [Phase 3]

  This document reports a Phase 3 trial update on using levofloxacin to prevent chemotherapy-related infection in patients with solid tumors o…

• CLINICAL_TRIALS trial_result · 2013-07-04
  Clinical Trial Update: Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors [Phase 2]

  Phase 2 trial evaluating combination chemotherapy with amifostine to treat malignant germ cell tumors in children; the study status is compl…

• CLINICAL_TRIALS trial_result · 2013-06-26
  Clinical Trial Update: Combination Chemotherapy in Treating Children With Non-testicular Malignant Germ Cell Tumors [Phase 2]

  A Phase 2 trial update evaluating a combination chemotherapy regimen for children with non-testicular malignant germ cell tumors, including …