Extensive-stage Small Cell Lung Cancer
📧 Sign up to get email alerts when something new happens for Extensive-stage Small Cell Lung Cancer.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC) [Phase 3]
A Phase 3 trial in first-line extensive-stage small-cell lung cancer compares Tarlatamab plus Durvalumab with Carboplatin and Etoposide to D…
-
CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease [Phase 1]
A Phase 1 clinical trial evaluating a patient-derived autologous B7-H3 CAR-T cell therapy in previously treated extensive-stage small cell l…
-
CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Bispecific T-Cell Engager Tarlatamab and TROP2 Targeted Antibody Drug Conjugate Sacituzumab Govitecan in Previously Treated Extensive-Stage Small Cell Lung Cancer and Extrapulmonary Neuroendocrine Cancer [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating Tarlatamab and Sacituzumab Govitecan in previously treated extensive-stage…
-
CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Study of Sacituzumab Govitecan With Atezolizumab/Durvalumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating sacituzumab govitecan with atezolizumab and durvalumab as maintenance therapy for extensive-stage small cell lung c…
-
CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Nab-Paclitaxel Combined With Local Therapy in Relapsed SCLC [Phase 2]
This is a Phase 2 trial evaluating nab-paclitaxel with local therapy for relapsed small cell lung cancer (extensive stage). The study status…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial [Phase 2, Phase 3]
The RAPTOR trial is evaluating the addition of radiation therapy to atezolizumab for extensive-stage small cell lung cancer and is currently…
-
CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Phase II Study of Platinum/Etoposide Plus Ivonescimab for Extensive-Stage Small Cell Lung Cancer [Phase 2]
A Phase II clinical trial updating the study of platinum/etoposide chemotherapy plus Ivonescimab for extensive-stage small cell lung cancer …
-
CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS). [Phase 3]
A Phase 3 trial comparing BMS-986489 (BMS-986012 + nivolumab fixed-dose combination) plus carboplatin and etoposide versus atezolizumab plus…
-
CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study Comparing BL-B01D1 Combined With Tislelizumab Versus Platinum-containing Chemotherapy Combined With Tislelizumab as First-line Treatment in Patients With Extensive-stage Small Cell Lung Cancer(PANKU-Lung07) [Phase 3]
This Phase 3 trial (PANKU-Lung07) compares BL-B01D1 plus tislelizumab versus platinum-containing chemotherapy plus tislelizumab as first-lin…
-
CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemotherapy [Phase 3]
Phase 3 trial (DAREON-Lung-1) evaluating Obrixtamig plus atezolizumab with carboplatin and etoposide versus standard chemotherapy in advance…
-
CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing Maintenance Therapy for Small Cell Lung Cancer in Patients With SLFN11 Positive Biomarker [Phase 2]
Phase 2 clinical trial sponsored by the National Cancer Institute evaluating maintenance therapy for extensive-stage small cell lung cancer …
-
CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Study of RYZ101 in Combination With SoC in Subjects With SSTR+ ES-SCLC [Phase 1]
This document describes an ongoing Phase 1 trial evaluating RYZ101 in combination with standard of care for somatostatin receptor-positive e…
-
CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Sacituzumab Tirumotecan in Combination With Anlotinib in Previously Treated Patients With Extensive-Stage Small Cell Lung Cancer (ES-SCLC) [Phase 2]
A Phase 2 clinical trial evaluating sacituzumab tirumotecan in combination with anlotinib for previously treated extensive-stage small cell …
-
CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: LB-100, Carboplatin, Etoposide, and Atezolizumab for the Treatment of Untreated Extensive-Stage Small Cell Lung Cancer [Phase 1]
Phase 1 trial evaluating LB-100 in combination with carboplatin, etoposide, and atezolizumab for untreated extensive-stage small cell lung c…
-
CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study [Phase 2]
Phase 2 PRISM trial uses biomarker tests to guide selection of personalized therapies for extensive-stage small cell lung cancer; currently …
-
CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Iadademstat + SBRT With Atezo in ES-SCLC [Phase 1]
Phase 1 study evaluating iadademstat in combination with SBRT and atezolizumab for extensive-stage small cell lung cancer; recruitment is on…
-
CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311) [Phase 1]
Phase 1 clinical trial evaluating Tarlatamab in combination with AB248 for extensive-stage small cell lung cancer; recruitment is ongoing.
-
CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Carboplatin/Cisplatin + Etoposide + Benmelstobart Sequential Benmelstobart Combined With Anlotinib Versus Carboplatin/Cisplatin + Etoposide + Tislelizumab Sequential Tislelizumab in the Treatment of Extensive Stage Small Cell Lung Cancer [Phase 2]
Phase 2 trial in extensive-stage small cell lung cancer comparing sequential Benmelstobart with Anlotinib to sequential Tislelizumab followi…
-
CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed ES-SCLC Patients in Combination With Carboplatin, Etoposide and Atezolizumab [Phase 1, Phase 2]
Clinical trial update on a Phase 1/2 study evaluating [177Lu]Lu-DOTA-TATE in combination with carboplatin, etoposide, and atezolizumab for n…
-
CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: SNB-101 for Treatment of Extensive Stage Small Cell Lung Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial of SNB-101 for extensive-stage small cell lung cancer is currently recruiting.
-
CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Study of ZG006 in Combination With PD-1/PD-L1 Immune Checkpoint Inhibitors as First-Line Standard Therapy in Participants With Extensive Stage Small-Cell Lung Cancer [Phase 1]
A Phase 1 trial evaluating ZG006 in combination with PD-1/PD-L1 inhibitors as first-line therapy for extensive-stage small cell lung cancer.…
-
CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES) [Phase 2]
This entry describes a Phase 2 trial investigating durvalumab with ablative radiation for small-cell lung cancer, currently recruiting.
-
CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Golidocitinib With PD-1 Inhibitors as Maintenance Treatment for Previously Untreated ES-SCLC [Phase 2]
A Phase 2 clinical trial evaluating golidocitinib in combination with PD-1 inhibitors as maintenance therapy for previously untreated extens…
-
CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Ifinatamab Deruxtecan (I-DXd) in Subjects With Pretreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC) [Phase 2]
Phase 2 clinical trial update on Ifinatamab Deruxtecan (I-DXd) for patients with pretreatment extensive-stage small cell lung cancer (ES-SCL…
-
CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Tislelizumab Combined With Chemotherapy Followed by Thoracic Consolidation Radiotherapy in the First-line Treatment of Extensive Stage Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating tislelizumab plus chemotherapy followed by thoracic consolidation radiotherapy as first-line treatment f…