Ewing Sarcoma
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CLINICAL_TRIALS trial_result · 2018-03-21Clinical Trial Update: HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors [Phase 1]
This update reports the completion of a Phase 1 clinical trial evaluating HSV-1716 in patients with non-CNS solid tumors, including rhabdomy…
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: 18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing Sarcoma [EARLY_Phase 1]
Early-phase clinical trial evaluating 18F-FLT PET and diffusion-weighted MRI to plan surgery and radiation therapy and measure response in n…
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FDA approval · 2017-11-09FDA Approved: DACTINOMYCIN — Original Application (Eugia US LLC)
FDA approved the original ANDA for dactinomycin (generic) to Eugia US LLC, enabling generic manufacturing and distribution of this anticance…
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CLINICAL_TRIALS trial_result · 2017-11-01Clinical Trial Update: A Phase II of Nivolumab Plus Ipilimumab in Non-resectable Sarcoma and Endometrial Carcinoma [Phase 2]
Phase II trial of nivolumab plus ipilimumab in non-resectable soft tissue and bone sarcomas, with exploration across several sarcoma subtype…
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CLINICAL_TRIALS trial_result · 2017-08-17Clinical Trial Update: A Phase I Trial Of The Humanized Anti-GD2 Antibody In Children And Adolescents With Neuroblastoma, Osteosarcoma, Ewing Sarcoma and Melanoma [Phase 1]
A Phase I trial of a humanized anti-GD2 antibody in children and adolescents with neuroblastoma, osteosarcoma, Ewing sarcoma, and melanoma h…
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CLINICAL_TRIALS guidance · 2017-07-02Clinical Trial Update: Informed Consent in Pediatric Cancer Trials
NCI provides guidance on informed consent practices for pediatric cancer clinical trials, highlighting considerations to protect children an…
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: Olaparib in Adults With Recurrent/Metastatic Ewing's Sarcoma [Phase 2]
Phase 2 trial evaluating olaparib in adults with recurrent/metastatic Ewing sarcoma has completed, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-05-17Clinical Trial Update: Evaluating Dactinomycin and Vincristine in Young Patients With Cancer
This ClinicalTrials.gov update reports on a completed pediatric cancer trial evaluating dactinomycin and vincristine.
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CLINICAL_TRIALS trial_result · 2017-05-16Clinical Trial Update: A Combined Study in Pediatric Cancer Patients for Dose Ranging and Efficacy/Safety of Plerixafor Plus Standard Regimens for Mobilization Versus Standard Regimens Alone [Phase 1, Phase 2]
Phase 1/2 pediatric trial evaluating dose-ranging and the efficacy/safety of adding plerixafor to standard mobilization regimens versus stan…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Study To Examine Toxicity Of Allogeneic Stem Cell Transplantation For Relapsed Or Therapy Refractory Ewings Sarcoma [Phase 1]
A Phase 1 clinical trial completed evaluating the toxicity of allogeneic stem cell transplantation in relapsed or therapy-refractory Ewing s…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Decitabine Followed by a Cancer Antigen Vaccine for Patients With Neuroblastoma and Sarcoma [Phase 1]
A Phase 1 trial evaluating decitabine followed by a cancer antigen vaccine in neuroblastoma and various sarcomas has completed.
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CLINICAL_TRIALS withdrawal · 2017-05-09Clinical Trial Update: A Phase I Study to Examine the Toxicity of Allogeneic Stem Cell Transplantation for Relapsed or Therapy Refractory Ewing Sarcoma [Phase 1]
Withdrawn: A Phase I clinical trial evaluating the toxicity of allogeneic stem cell transplantation for relapsed or therapy-refractory Ewing…
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CLINICAL_TRIALS trial_result · 2017-05-08Clinical Trial Update: Quantitative Imaging Biomarkers of Treatment Response in Osteosarcoma and Ewing Sarcoma [NA]
The update indicates that a Vanderbilt-Ingram Cancer Center trial evaluating quantitative imaging biomarkers of treatment response in osteos…
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CLINICAL_TRIALS trial_result · 2017-02-02Clinical Trial Update: Cyclophosphamide, Doxorubicin, Vincristine w/ Irinotecan and Temozolomide in Ewings Sarcoma [Phase 2]
A Phase 2 trial evaluating a multi-agent regimen of cyclophosphamide, doxorubicin, vincristine with irinotecan and temozolomide in Ewing sar…
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CLINICAL_TRIALS trial_result · 2016-10-27Clinical Trial Update: QUILT-3.025: A Phase 2 Study of AMG 479 in Relapsed or Refractory Ewing's Family Tumor and Desmoplastic Small Round Cell Tumors [Phase 2]
Phase 2 results for AMG 479 in relapsed or refractory Ewing sarcoma family tumors, including Askin's tumor and desmoplastic small round cell…
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CLINICAL_TRIALS trial_result · 2016-10-19Clinical Trial Update: Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors [Phase 2]
Phase 2 trial update from St. Jude investigating a therapy for Desmoplastic Small Round Cell Tumor and Ewing sarcoma; results were posted in…
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CLINICAL_TRIALS research · 2016-07-14Clinical Trial Update: Genetic Biomarkers in Saliva Samples From Patients With Ewing Sarcoma
Clinical trial update examining genetic biomarkers in saliva from patients with Ewing sarcoma/PNET; the study has completed.
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: Biomarker in Tissue Samples From Patients With Ewing Sarcoma
This clinical trial update reports findings on a biomarker study in tissue samples from patients with Ewing sarcoma.
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: PK/PD of XM22 in Children With Ewing Family of Tumors or Rhabdomyosarcoma [Phase 1]
This Phase 1 study reports on the pharmacokinetics and pharmacodynamics of XM22 in pediatric patients with Ewing sarcoma or rhabdomyosarcoma…
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CLINICAL_TRIALS trial_result · 2016-05-17Clinical Trial Update: Study of Tumor Samples From Patients With Ewing Sarcoma
The study analyzing tumor samples from patients with localized Ewing sarcoma and peripheral primitive neuroectodermal tumor has completed.
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CLINICAL_TRIALS trial_result · 2016-04-28Clinical Trial Update: Functional and Clinical Long-Term Outcome of Ewing Sarcoma Treatment
A completed clinical trial from University Hospital Muenster reports on the functional and clinical long-term outcomes of treatment for Ewin…
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CLINICAL_TRIALS trial_result · 2016-02-15Clinical Trial Update: Mithramycin for Children and Adults With Solid Tumors or Ewing Sarcoma [Phase 1, Phase 2]
NCI-sponsored Phase 1/2 trial of mithramycin in children and adults with solid tumors or Ewing sarcoma was terminated; results were posted i…
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CLINICAL_TRIALS trial_result · 2016-01-21Clinical Trial Update: Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors in Pediatric Patients [Phase 1]
Phase 1 safety study of a recombinant vaccinia virus (JX-594/Pexa-Vec) for refractory pediatric solid tumors. The trial has completed and en…
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CLINICAL_TRIALS withdrawal · 2016-01-12Clinical Trial Update: Post-operative Radiotherapy in Poor Responders Ewing's Sarcoma Patients [Phase 3]
A Phase 3 clinical trial evaluating post-operative radiotherapy in poor responders with Ewing sarcoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-12-11Clinical Trial Update: A Study to Determine the Activity of Robatumumab (SCH 717454) in Participants With Relapsed Osteosarcoma or Ewing's Sarcoma (MK-7454-002/P04720) [Phase 2]
Phase 2 study of robatumumab in relapsed osteosarcoma or Ewing's sarcoma was terminated; results posted in 2015.