Ewing Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: SM-88 Maintenance Therapy for Advanced Ewing's Sarcoma and as Salvage Therapy for Sarcoma [Phase 2]
Clinical trial update for SM-88 as maintenance therapy in advanced Ewing's sarcoma and as salvage therapy for sarcoma (Phase 2); trial is cu…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers [Phase 1, Phase 2]
Phase 1/2 trial update evaluating nivolumab plus ABI-009 (nab-rapamycin) in patients with advanced sarcoma and selected cancers, with result…
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Intensity-Modulated Radiation Therapy in Treating Younger Patients With Lung Metastases [NA]
Clinical trial update indicates completion of a study evaluating intensity-modulated radiation therapy in younger patients with lung metasta…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors [Phase 2]
Phase 2 trial evaluating neoadjuvant dual checkpoint inhibition with cryoablation in relapsed/refractory pediatric solid tumors has complete…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors [Phase 1]
Phase 1 trial completion evaluating MR-guided High Intensity Focused Ultrasound (HIFU) for relapsed or refractory pediatric solid tumors, in…
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: TK216 in Patients With Relapsed or Refractory Ewing Sarcoma [Phase 1, Phase 2]
Clinical trial update for TK216 in relapsed or refractory Ewing sarcoma (Phase 1/2) shows the study was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 update on erdafitinib for FGFR-mutant relapsed or refractory pediatric cancers enrolled in the Pediatric MATCH trial; results were p…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Phase 1, First-in-human Study of Oral TP-1287 in Patients with Advanced Solid Tumors [Phase 1]
Phase 1 first-in-human study of oral TP-1287 in patients with advanced solid tumors, including specific sarcoma subtypes, has been terminate…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 Pediatric MATCH trial evaluating samotolisib in pediatric patients with relapsed or refractory tumors harboring TSC or PI3K/mTOR mut…
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: A Study of KC1036 in Adolescents With Advanced Ewing Sarcoma [Phase 2]
This is a Phase 2 study of KC1036 in adolescents with advanced Ewing Sarcoma. The trial is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-17Clinical Trial Update: Palbociclib + Ganitumab In Ewing Sarcoma [Phase 2]
Phase 2 trial of palbociclib plus ganitumab in Ewing sarcoma has been terminated with results posted in July 2024.
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: A Study of Surufatinib in Combination With Gemcitabine in Pediatric, Adolescent, and Young Adult Patients With Recurrent or Refractory Solid Tumors [Phase 1, Phase 2]
This completed Phase 1/2 study evaluated the safety and preliminary efficacy of combining surufatinib with gemcitabine in pediatric, adolesc…
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Study of Genistein in Pediatric Oncology Patients (UVA-Gen001) [Phase 2]
Phase 2 pediatric trial of Genistein for various cancers was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial) [Phase 2]
A pediatric MATCH phase 2 trial assessed olaparib in children with relapsed or refractory advanced solid tumors or non-Hodgkin lymphoma carr…
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CLINICAL_TRIALS trial_result · 2023-12-04Clinical Trial Update: Safety, Tolerability, Efficacy and Pharmacokinetics of Copanlisib in Pediatric Patients [Phase 1, Phase 2]
Clinical trial update on Copanlisib in pediatric patients with relapsed or refractory solid tumors or lymphoma, including neuroblastoma, wit…
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: SARC024: A Blanket Protocol to Study Oral Regorafenib in Patients With Selected Sarcoma Subtypes [Phase 2]
Phase 2 trial evaluating oral regorafenib across selected sarcoma subtypes has completed enrollment with results posted.
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CLINICAL_TRIALS trial_result · 2023-10-27Clinical Trial Update: Use of GnRHa During Chemotherapy for Fertility Protection [Phase 3]
Phase 3 trial investigating GnRHa during chemotherapy to protect fertility in cancer patients; currently recruiting.
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CLINICAL_TRIALS trial_result · 2023-09-13Clinical Trial Update: Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
This Phase 2 Pediatric MATCH trial evaluated vemurafenib in children with BRAF V600-mutant relapsed or refractory advanced solid tumors, non…
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CLINICAL_TRIALS trial_result · 2023-09-08Clinical Trial Update: ADI-PEG 20 in Combination With Gemcitabine and Docetaxel for the Treatment of Soft Tissue Sarcoma, Osteosarcoma, Ewing's Sarcoma, and Small Cell Lung Cancer [Phase 2]
Phase 2 trial of ADI-PEG 20 in combination with gemcitabine and docetaxel for soft tissue sarcoma, osteosarcoma, Ewing's sarcoma, and small …
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CLINICAL_TRIALS trial_result · 2023-08-14Clinical Trial Update: Indo-cyanine Green (ICG) in Paediatric Oncology MIS [Phase 4]
Phase 4 trial update on using Indo-cyanine Green (ICG) in pediatric oncology, with completed status.
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CLINICAL_TRIALS trial_result · 2023-08-03Clinical Trial Update: Comparison of Combination Chemotherapy Regimens in Treating Patients With Ewing's Sarcoma or Neuroectodermal Tumor [Phase 3]
A Phase 3 trial comparing combination chemotherapy regimens in patients with Ewing's Sarcoma/PNET, completed.
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CLINICAL_TRIALS trial_result · 2023-08-01Clinical Trial Update: A Rollover Protocol to Allow for Continued Access to the LSD1 Inhibitor Seclidemstat (SP-2577) [Phase 1, Phase 2]
A rollover protocol update is described to allow continued access to the LSD1 inhibitor seclidemstat (SP-2577) in ongoing Phase 1/Phase 2 tr…
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CLINICAL_TRIALS trial_result · 2023-05-16Clinical Trial Update: Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 Pediatric MATCH trial evaluating Ulixertinib for MAPK-pathway-mutant tumors in children, including advanced solid tumors, Non-Hodgki…
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CLINICAL_TRIALS trial_result · 2023-04-26Clinical Trial Update: A Trial For Participants With Ewing's Sarcoma Treated With Vigil in Combination With Irinotecan and Temozolomide [Phase 3]
A Phase 3 trial evaluating Vigil in combination with irinotecan and temozolomide for Ewing sarcoma has been terminated; results posted in 20…
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CLINICAL_TRIALS trial_result · 2023-03-24Clinical Trial Update: A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer [Phase 1, Phase 2]
A phase 1/2 trial evaluating bempegaldesleukin (BEMPEG) in combination with nivolumab in pediatric and young adult patients with recurrent o…