Estrogen Receptor-positive Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Neoadjuvant and Adjuvant Ribociclib and ET for Clinically High-risk ER+ and HER2- Breast Cancer [Phase 2]
A Phase 2 neoadjuvant and adjuvant trial evaluating ribociclib with endocrine therapy for clinically high-risk ER-positive, HER2-negative br…
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CLINICAL_TRIALS trial_result · 2025-02-27Clinical Trial Update: Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer [Phase 2]
Phase 2 clinical trial update evaluating correlation between clinical response and pathologic response in patients with early breast cancer.
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CLINICAL_TRIALS research · 2025-02-26Clinical Trial Update: To Identify Primary Resistance to CDK4/6 Inhibitors in Breast Cancer
A clinical trial update describing a study to identify primary resistance to CDK4/6 inhibitors in breast cancer.
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CLINICAL_TRIALS trial_result · 2025-02-25Clinical Trial Update: Trial of H3B-6545, in Women With Locally Advanced or Metastatic Estrogen Receptor-positive, HER2 Negative Breast Cancer [Phase 1, Phase 2]
Completed Phase 1/2 trial evaluating H3B-6545 in women with locally advanced or metastatic ER-positive, HER2-negative breast cancer; results…
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Radiation Therapy, Palbociclib, and Hormone Therapy in Treating Breast Cancer Patients With Bone Metastasis [Phase 2]
A Phase 2 clinical trial evaluating the combination of radiation therapy, palbociclib, and endocrine (hormone) therapy in patients with estr…
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Evaluation of Lasofoxifene Combined With Abemaciclib in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation [Phase 2]
Phase 2 trial evaluating lasofoxifene in combination with abemaciclib in advanced or metastatic ER+/HER2- breast cancer with ESR1 mutation h…
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: A Study of AC682 for the Treatment of Locally Advanced or Metastatic ER+ Breast Cancer [Phase 1]
A Phase 1 clinical trial evaluating AC682 for locally advanced or metastatic estrogen receptor-positive breast cancer has been terminated.
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: A Study to Investigate the Biological Effects of AZD9833 in Women With ER-positive, HER2 Negative Primary Breast Cancer [Phase 2]
A Phase 2 study evaluating the biological effects of AZD9833 in women with ER-positive, HER2-negative primary breast cancer has completed an…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Alcohol and Breast Cancer (ABC) Trial [NA]
The Alcohol and Breast Cancer (ABC) trial evaluating the relationship between alcohol exposure and outcomes in estrogen receptor-positive br…
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast [Phase 2]
Phase 2 trial testing an active form of tamoxifen (4-hydroxytamoxifen) delivered through the breast skin to treat ductal carcinoma in situ (…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: AZD9833 China PK Study [Phase 1]
AstraZeneca's AZD9833 Phase 1 pharmacokinetic study in China for estrogen receptor–positive, HER2-negative metastatic breast cancer has comp…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: To Reduce the Use of Chemotherapy in Postmenopausal Patients With ER-positive and HER2-positive Breast Cancer (TOUCH) [Phase 2]
Phase 2 TOUCH trial updates results on reducing chemotherapy use in postmenopausal patients with ER-positive and HER2-positive breast cancer…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Study to Evaluate the Extended Overall Survival (OS) Data From PARSIFAL Study (The PARSIFAL-LONG Study)
This clinical trial update provides extended overall survival data from the PARSIFAL study (PARSIFAL-LONG) in metastatic/advanced breast can…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: A Study Evaluating the Efficacy and Safety of De Trastuzumab (T-DXd) in Combination with Immunotherapy for the Neoadjuvant Treatment of HR-positive HER2 Low-expressing Chinese Patients with Early-stage Breast Cancer [Phase 2]
Phase 2 clinical trial evaluating trastuzumab deruxtecan in combination with immunotherapy as neoadjuvant treatment for HR-positive, HER2-lo…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Palbociclib in Combination With Fulvestrant or Letrozole in Patients With ER+, HER2- Advanced Breast Cancer [Phase 2]
Phase 2 trial results update for palbociclib in combination with fulvestrant or letrozole in ER-positive, HER2-negative metastatic breast ca…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: [18F]Fluoroestradiol-PET/CT Companion Imaging Study to the FORESEE Trial [EARLY_Phase 1]
The EARLY Phase 1 study of [18F]Fluoroestradiol-PET/CT as companion imaging to the FORESEE trial has been terminated.
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Efficacy and Safety of Ribociclib Combined With AI Versus Physician&Amp;#39;s Choice of Chemotherapy Sequential Endocrine Therapy in ER Middle-low-expression/HER2-negative Advanced Breast Cancer (Rachel) [Phase 2]
Phase 2 clinical trial evaluating ribociclib in combination with an aromatase inhibitor versus physician’s choice of chemotherapy sequential…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: A 2-Week Ketogenic Diet in Combination With Letrozole to Modulate PI3K Signaling in ER+ Breast Cancer [EARLY_Phase 1]
An early-phase 1 study evaluating a two-week ketogenic diet in combination with letrozole to modulate PI3K signaling in estrogen receptor-po…
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CLINICAL_TRIALS research · 2024-10-02Clinical Trial Update: Early Changes in Metabolic Health in Breast Cancer Patients Initiating Endocrine Therapy
A clinical trial update from Aarhus University Hospital outlines early metabolic health changes observed in breast cancer patients starting …
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CLINICAL_TRIALS other · 2024-08-09Clinical Trial Update: Safety of Elacestrant in ER+/HER2- and ESR1 Mutations MBC
Clinical trial update shows ongoing recruitment for assessing the safety of elacestrant in ER-positive, HER2-negative metastatic breast canc…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Palbociclib in Combination With Tamoxifen as First Line Therapy for Metastatic Hormone Receptor Positive Breast Cancer [Phase 2]
A Phase 2 trial evaluating palbociclib in combination with tamoxifen as first-line therapy for metastatic hormone receptor-positive, HER2-ne…
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CLINICAL_TRIALS research · 2024-07-23Clinical Trial Update: BYL719 and Letrozole in Post-Menopausal Patients With Hormone Receptor-Positive Metastatic Breast Cancer [Phase 1]
Phase 1 clinical trial evaluating BYL719 (alpelisib) with letrozole in post-menopausal women with hormone receptor-positive metastatic breas…
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CLINICAL_TRIALS research · 2024-06-26Clinical Trial Update: Characterization of Biophysical and Mechanical Parameters on Skin of Breast Cancer Patients
Recruiting clinical study evaluating biophysical and mechanical properties of skin in patients with breast cancer, including estrogen recept…
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Pre-operative Immunotherapy Combination Strategies in Breast Cancer [Phase 2]
This clinical trial update reports a Phase 2 study of pre-operative immunotherapy combination strategies in breast cancer, including estroge…
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CLINICAL_TRIALS research · 2024-06-10Clinical Trial Update: Immunotherapy, Hormone Therapy, and AKT Inhibitor for Premenopausal ER Positive MBC [Phase 2]
Phase 2 clinical trial evaluating a combination of immunotherapy, hormone therapy, and an AKT inhibitor for premenopausal, ER-positive metas…