Estrogen Receptor-positive Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: A Study to Investigate the Biological Effects of AZD9833 in Women With ER-positive, HER2 Negative Primary Breast Cancer [Phase 2]
A Phase 2 study evaluating the biological effects of AZD9833 in women with ER-positive, HER2-negative primary breast cancer has completed an…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Alcohol and Breast Cancer (ABC) Trial [NA]
The Alcohol and Breast Cancer (ABC) trial evaluating the relationship between alcohol exposure and outcomes in estrogen receptor-positive br…
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast [Phase 2]
Phase 2 trial testing an active form of tamoxifen (4-hydroxytamoxifen) delivered through the breast skin to treat ductal carcinoma in situ (…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: AZD9833 China PK Study [Phase 1]
AstraZeneca's AZD9833 Phase 1 pharmacokinetic study in China for estrogen receptor–positive, HER2-negative metastatic breast cancer has comp…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: To Reduce the Use of Chemotherapy in Postmenopausal Patients With ER-positive and HER2-positive Breast Cancer (TOUCH) [Phase 2]
Phase 2 TOUCH trial updates results on reducing chemotherapy use in postmenopausal patients with ER-positive and HER2-positive breast cancer…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Study to Evaluate the Extended Overall Survival (OS) Data From PARSIFAL Study (The PARSIFAL-LONG Study)
This clinical trial update provides extended overall survival data from the PARSIFAL study (PARSIFAL-LONG) in metastatic/advanced breast can…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: A Study Evaluating the Efficacy and Safety of De Trastuzumab (T-DXd) in Combination with Immunotherapy for the Neoadjuvant Treatment of HR-positive HER2 Low-expressing Chinese Patients with Early-stage Breast Cancer [Phase 2]
Phase 2 clinical trial evaluating trastuzumab deruxtecan in combination with immunotherapy as neoadjuvant treatment for HR-positive, HER2-lo…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Palbociclib in Combination With Fulvestrant or Letrozole in Patients With ER+, HER2- Advanced Breast Cancer [Phase 2]
Phase 2 trial results update for palbociclib in combination with fulvestrant or letrozole in ER-positive, HER2-negative metastatic breast ca…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: [18F]Fluoroestradiol-PET/CT Companion Imaging Study to the FORESEE Trial [EARLY_Phase 1]
The EARLY Phase 1 study of [18F]Fluoroestradiol-PET/CT as companion imaging to the FORESEE trial has been terminated.
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Efficacy and Safety of Ribociclib Combined With AI Versus Physician&Amp;#39;s Choice of Chemotherapy Sequential Endocrine Therapy in ER Middle-low-expression/HER2-negative Advanced Breast Cancer (Rachel) [Phase 2]
Phase 2 clinical trial evaluating ribociclib in combination with an aromatase inhibitor versus physician’s choice of chemotherapy sequential…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: A 2-Week Ketogenic Diet in Combination With Letrozole to Modulate PI3K Signaling in ER+ Breast Cancer [EARLY_Phase 1]
An early-phase 1 study evaluating a two-week ketogenic diet in combination with letrozole to modulate PI3K signaling in estrogen receptor-po…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Palbociclib in Combination With Tamoxifen as First Line Therapy for Metastatic Hormone Receptor Positive Breast Cancer [Phase 2]
A Phase 2 trial evaluating palbociclib in combination with tamoxifen as first-line therapy for metastatic hormone receptor-positive, HER2-ne…
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Pre-operative Immunotherapy Combination Strategies in Breast Cancer [Phase 2]
This clinical trial update reports a Phase 2 study of pre-operative immunotherapy combination strategies in breast cancer, including estroge…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Evaluation of Endocrine Therapy Effects of Host Immunity in Early Stage Breast Cancer
This update reports on a completed clinical trial evaluating how endocrine therapy influences host immune responses in early-stage breast ca…
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CLINICAL_TRIALS trial_result · 2023-12-13Clinical Trial Update: 68-Ga-RM2 PET/MRI in Imaging Patients With Estrogen Receptor-Positive Breast Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating 68-Ga-RM2 PET/MRI for imaging estrogen receptor-positive breast cancer has completed with results post…
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CLINICAL_TRIALS trial_result · 2023-11-09Clinical Trial Update: Neoadjuvant Pembrolizumab + Decitabine Followed by Std Neoadj Chemo for Locally Advanced HER2- Breast Ca [Phase 2]
Phase 2 trial evaluating neoadjuvant pembrolizumab plus decitabine followed by standard neoadjuvant chemotherapy for locally advanced HER2-n…
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CLINICAL_TRIALS trial_result · 2023-08-31Clinical Trial Update: Pembrolizumab and Tamoxifen With or Without Vorinostat for the Treatment of Estrogen Receptor Positive Breast Cancer [Phase 2]
Phase 2 trial investigating pembrolizumab with or without vorinostat and tamoxifen for estrogen receptor-positive breast cancer; trial termi…
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CLINICAL_TRIALS trial_result · 2023-03-30Clinical Trial Update: Phase 2 Study of Amcenestrant (SAR439859) Versus Physician's Choice in Locally Advanced or Metastatic ER-positive Breast Cancer [Phase 2]
Phase 2 study comparing amcenestrant to physician's choice in locally advanced or metastatic estrogen receptor-positive breast cancer. The t…
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CLINICAL_TRIALS trial_result · 2023-03-10Clinical Trial Update: A Study Evaluating the Efficacy and Safety of Giredestrant Compared With Physician's Choice of Endocrine Monotherapy in Participants With Previously Treated Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (acelERA Breast Cancer) [Phase 2]
This clinical trial update reports on a Phase 2 study comparing giredestrant with physician's choice of endocrine therapy in previously trea…
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CLINICAL_TRIALS trial_result · 2023-02-21Clinical Trial Update: Serial FES PET/CT to Measure Hormone Expression in Patients Undergoing Endocrine Targeted Therapy [Phase 2]
Phase 2 clinical trial update describing the use of serial FES PET/CT imaging to assess estrogen receptor expression in patients with estrog…
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CLINICAL_TRIALS trial_result · 2023-02-21Clinical Trial Update: Dalpiciclib in Combination With Exemestane and Trastuzumab Plus Pyrotinib in Early Triple Positive Breast Cancer [Phase 2]
Phase 2 trial exploring dalpiciclib in combination with exemestane, trastuzumab, and pyrotinib for early triple-positive breast cancer (ER+,…
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CLINICAL_TRIALS trial_result · 2023-02-02Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Giredestrant Plus Palbociclib Compared With Anastrozole Plus Palbociclib for Postmenopausal Women With Estrogen Receptor-Positive and HER2-Negative Untreated Early Breast Cancer (coopERA Breast Cancer) [Phase 2]
Phase 2 trial comparing giredestrant plus palbociclib to anastrozole plus palbociclib in untreated postmenopausal ER-positive, HER2-negative…
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CLINICAL_TRIALS trial_result · 2022-06-02Clinical Trial Update: PD 0332991 and Anastrozole for Stage 2 or 3 Estrogen Receptor Positive and HER2 Negative Breast Cancer [Phase 2]
Phase 2 trial evaluating palbociclib in combination with anastrozole for Stage 2-3 estrogen receptor-positive, HER2-negative breast cancer; …
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CLINICAL_TRIALS trial_result · 2022-05-18Clinical Trial Update: Ribociclib and Aromatase Inhibitor in Treating Older Participants With Hormone Receptor Positive Metastatic Breast Cancer [Phase 2]
Phase 2 clinical trial evaluating ribociclib in combination with an aromatase inhibitor for older adults with estrogen receptor-positive, HE…
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CLINICAL_TRIALS trial_result · 2022-04-05Clinical Trial Update: Phase II Study of Everolimus Beyond Progression [Phase 2]
Phase II trial evaluating Everolimus beyond progression in breast cancer was terminated with posted results.