Esophageal Neoplasms
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-02Clinical Trial Update: Effects of Preoperative Enteral Immunonutrition for Esophageal Cancer Patients Given Neoadjuvant Chemoradiotherapy [Phase 3]
Phase 3 trial assessing preoperative enteral immunonutrition in esophageal cancer patients receiving neoadjuvant chemoradiotherapy.
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Clinical Study on the Effect of Massaging Tian Tu Acupoint on Coughing After Esophageal Surgery [NA]
This clinical trial is investigating whether massage at the Tian Tu acupoint can reduce coughing after esophageal surgery in patients with e…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Weekly Cisplatin/Irinotecan and Radiotherapy in Patients With Locally Advanced Esophageal Cancer: Phase II Trial [Phase 2]
A Phase II trial evaluating weekly cisplatin and irinotecan with radiotherapy in locally advanced esophageal cancer has been completed.
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Proximal Versus Total Gastrectomy for Locally Advanced Siewert Type II-III Gastroesophageal Junction Cancer [NA]
A clinical trial is recruiting to compare proximal versus total gastrectomy for locally advanced gastroesophageal junction cancer (Siewert T…
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: Esophageal Cancer Multimodal Prehabilitation Study [NA]
The Massachusetts General Hospital–sponsored esophageal cancer multimodal prehabilitation trial has completed.
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005) [Phase 2]
Merck completed a Phase 2 trial (MK-7684A-005) evaluating MK-7684A with or without other anticancer therapies in selected solid tumors.
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: Comparison of 0.4% Hyaluronic Acid Solution Versus Hydroxyethylamide Solution in Submucosal Endoscopic Resections [NA]
This clinical trial compares 0.4% hyaluronic acid solution with hydroxyethylamide solution for submucosal injections during endoscopic resec…
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: Barrett's Esophagus Related Neoplasia (BERN) Project
This ClinicalTrials.gov entry indicates the Barrett's Esophagus Related Neoplasia (BERN) Project is currently recruiting to study Barrett's …
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: Automatic Diagnosis of Early Esophageal Squamous Neoplasia Using pCLE With AI
A completed clinical trial from Shandong University evaluating AI-assisted automatic diagnosis of early esophageal neoplasia using confocal …
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CLINICAL_TRIALS research · 2024-11-14Clinical Trial Update: Tranilast Vs. Steroids to Prevent Esophageal Stricture (TAPES) After Endoscopic Resection for Superficial Neoplasms [Phase 2]
Phase 2 trial comparing tranilast to steroids to prevent esophageal stricture after endoscopic resection for superficial esophageal neoplasm…
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CLINICAL_TRIALS research · 2024-08-28Clinical Trial Update: Feasibility and Added Value of the TRACMOTION Device for ESD [NA]
This clinical trial update discusses the feasibility and potential added value of the TRACMOTION device to aid endoscopic submucosal dissect…
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CLINICAL_TRIALS withdrawal · 2024-06-27Clinical Trial Update: Monopolar and Bipolar in Esophageal ESD [NA]
A Baylor College of Medicine–sponsored clinical trial evaluating monopolar and bipolar energy for esophageal endoscopic submucosal dissectio…
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CLINICAL_TRIALS trial_result · 2023-08-09Clinical Trial Update: Tranexamic Acid During Upper GI Endoscopic Resection Procedures [Phase 4]
Clinical trial update for tranexamic acid as an adjunct in upper GI endoscopic resections; Phase 4 study with unknown status.
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CLINICAL_TRIALS trial_result · 2023-03-16Clinical Trial Update: Oral Prednisolone to Prevent Esophageal Stricture After RFA for Long-segment Esophageal Neoplasia [Phase 4]
Phase 4 trial investigating oral prednisolone to prevent esophageal stricture after radiofrequency ablation for long-segment esophageal neop…
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CLINICAL_TRIALS trial_result · 2022-11-30Clinical Trial Update: [68Ga]Ga-ABY-025 PET for Quantification of HER2-status in Solid Tumors [Phase 2]
A Phase 2 clinical trial update evaluating [68Ga]Ga-ABY-025 PET for quantifying HER2 status in solid tumors, including esophageal and gastri…
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CLINICAL_TRIALS trial_result · 2022-04-05Clinical Trial Update: Continuous 24h Intravenous Infusion of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in People With Primary Thoracic Malignancies or Carcinomas, Sarcomas or Germ Cell Neoplasms With Pleuropulmonary Metastases [Phase 1, Phase 2]
Phase 1/2 trial evaluating continuous 24-hour IV mithramycin for thoracic malignancies with pleuropulmonary metastases was terminated; resul…
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CLINICAL_TRIALS withdrawal · 2022-02-23Clinical Trial Update: Removal of the Evolution® Esophageal Stent - Fully Covered [NA]
Clinical trial update noting completion and removal of the Evolution esophageal stent product from research, with posted results.
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CLINICAL_TRIALS trial_result · 2022-01-03Clinical Trial Update: Study of Simultaneous Modulated Accelerated Radiation Therapy Concurrent With Chemotherapy to Treat Esophageal Cancer [Phase 2]
Phase 2 clinical trial evaluating simultaneous modulated accelerated radiation therapy with concurrent chemotherapy for esophageal neoplasms…
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CLINICAL_TRIALS trial_result · 2021-12-21Clinical Trial Update: PD-1 Inhibitor Combined With Neoadjuvant Chemotherapy in Subjects With Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial exploring a PD-1 inhibitor combined with neoadjuvant chemotherapy in resectable locally advanced thoracic esophageal …
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CLINICAL_TRIALS trial_result · 2021-10-05Clinical Trial Update: Thromboprophylaxis in Oesophageal Cancer Patients [Phase 4]
Phase 4 clinical trial update on thromboprophylaxis in esophageal cancer patients.
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CLINICAL_TRIALS trial_result · 2021-08-19Clinical Trial Update: TQB2450 Solution for Injection (TQB2450)+Paclitaxel+Cisplatin ± Anlotinib in the Treatment of Esophageal Cancer. [Phase 2]
Phase 2 trial update for TQB2450 plus paclitaxel and cisplatin with or without anlotinib in esophageal neoplasms (esophageal cancer).
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CLINICAL_TRIALS trial_result · 2021-07-06Clinical Trial Update: First-line Esophageal Carcinoma Study With Pembrolizumab Plus Chemo vs. Chemo (MK-3475-590/KEYNOTE-590) [Phase 3]
Phase 3 study MK-3475-590 (KEYNOTE-590) evaluating pembrolizumab plus chemotherapy versus chemotherapy in first-line esophageal neoplasms ha…
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CLINICAL_TRIALS trial_result · 2021-03-26Clinical Trial Update: Trial of S-1 Maintenance Therapy in Metastatic Esophagogastric Cancer [Phase 2]
Phase 2 trial evaluating S-1 maintenance therapy in unresectable, locally advanced or metastatic gastric/GEJ adenocarcinoma has been complet…
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CLINICAL_TRIALS trial_result · 2021-01-26Clinical Trial Update: Efficacy and Safety of Apatinib for Recurrent or Metastatic Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 trial update on apatinib for recurrent or metastatic esophageal squamous cell carcinoma showing efficacy and safety results.
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CLINICAL_TRIALS trial_result · 2020-08-28Clinical Trial Update: A Diagnostic Study of the Advanced Endoscopy to Detect Early Esophageal Cancer [NA]
A completed diagnostic study evaluating advanced endoscopy techniques to detect early esophageal cancer; results posted in 2020.