Escherichia Coli Infection
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Bacteriophage Therapy in Spinal Cord Injury Patients With Bacteriuria [Phase 1]
Phase 1 clinical trial assessing bacteriophage therapy for bacteriuria in spinal cord injury patients; currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Role of the NLRP3 Inflammasome in Escherichia Coli and Staphylococcus Aureus Bacteria
A clinical trial update indicates the study on the role of the NLRP3 inflammasome in Escherichia coli and Staphylococcus aureus infections h…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Cefotetan Therapy for Escherichia Coli Infections [Phase 2]
This entry reports a Phase 2 clinical trial evaluating cefotetan for Escherichia coli infections, including ESBL-producing strains, which is…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Safety of Combined Intravenous Antibiotic and Bacteriophage Therapy in Adults With Cystic Fibrosis and Antibiotic-Resistant Lung Infections [Phase 1]
Phase 1 trial update describing safety considerations for combining intravenous antibiotics with bacteriophage therapy in adults with cystic…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant [Phase 1, Phase 2]
Phase 1b/2a randomized double-blind trial to evaluate safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of …
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Extended Tricyle Project Indonesia for Extended-spectrum Beta-lactamase Positive Klebsiella Pneumoniae and Escherichia Coli
A clinical trial update for Extended Tricycle Project Indonesia assessing carriage of ESBL-positive Escherichia coli and Klebsiella pneumoni…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Health Impacts of Street Vended Fruits [NA]
Completed clinical trial from Bangladesh Agricultural University evaluating health impacts and microbial contamination of street-vended frui…
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CLINICAL_TRIALS trial_result · 2025-03-03Clinical Trial Update: Developing Microbials to Fight Extended-spectrum Beta-lactamase (ESBL)-Producing Escherichia Coli
The document reports a clinical trial update on developing microbial therapies to combat ESBL-producing Escherichia coli, noting the trial i…
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CLINICAL_TRIALS other · 2025-02-07Clinical Trial Update: An Open Clinical Trial of the Safety and Efficacy of the Drug Fluorothiazinone, 300 Mg Tablets with the Participation of Adult Patients with Chronic Bacterial Cystitis" [Phase 3]
Phase 3 clinical trial update for Fluorothiazinone (300 mg) in adults with chronic bacterial cystitis; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-01-13Clinical Trial Update: Perinatal Transmission of MDR Bacteria
This document reports a clinical trial update on perinatal transmission of multi-drug resistant bacteria, focusing on Escherichia coli infec…
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CLINICAL_TRIALS trial_result · 2019-07-08Clinical Trial Update: Safety Study of Chimeric Vaccine to Prevent ETEC Diarrhea [Phase 1]
Phase 1 safety study of a chimeric vaccine to prevent ETEC diarrhea has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-06-14Clinical Trial Update: Epidemiology of Community - Associated Extended-spectrum Beta-lactamases (ESBL) Producing Escherichia Coli
Completed clinical trial investigating the epidemiology of community-associated ESBL-producing Escherichia coli causing Enterobacteriaceae i…
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CLINICAL_TRIALS trial_result · 2017-11-27Clinical Trial Update: RCT Meropenem vs Piperacillin-Tazobactam for Definitive Treatment of BSI's Due to Ceftriaxone Non-susceptible Escherichia Coli and Klebsiella Spp. [Phase 4]
A Phase 4 randomized trial comparing meropenem to piperacillin-tazobactam for definitive treatment of bloodstream infections caused by ceftr…
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CLINICAL_TRIALS research · 2017-06-29Clinical Trial Update: Trial of Low-cost Microbiological Water Test Kits [NA]
This update reports on a completed clinical trial evaluating low-cost microbiological water test kits, designed to detect contaminants linke…
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CLINICAL_TRIALS trial_result · 2015-12-17Clinical Trial Update: Antibiotic Resistant Community-Acquired E. Coli
A completed clinical trial update from the University of Pittsburgh evaluating antibiotic-resistant, community-acquired Escherichia coli inf…
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CLINICAL_TRIALS trial_result · 2015-08-27Clinical Trial Update: The Effect of Probiotics on E. Coli-induced Gastroenteritis [NA]
This update notes the completion of a clinical trial evaluating the effect of probiotics on E. coli-induced gastroenteritis. The snippet doe…
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CLINICAL_TRIALS research · 2015-07-24Clinical Trial Update: Evaluation of Phage Therapy for the Treatment of Escherichia Coli and Pseudomonas Aeruginosa Wound Infections in Burned Patients [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial update evaluating Phagenix's bacteriophage therapy for wound infections caused by Escherichia coli and Pseu…
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CLINICAL_TRIALS trial_result · 2015-06-24Clinical Trial Update: Colonization With Extended-Spectrum Beta-Lactamase (ESBL)-Producing Organisms
A completed clinical trial update describing colonization with ESBL-producing organisms in participants, involving Escherichia coli infectio…
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CLINICAL_TRIALS withdrawal · 2014-12-08Clinical Trial Update: Ampicillin-sulbactam Resistant E.Coli at UPMC
A clinical trial evaluating ampicillin-sulbactam in Escherichia coli infections at UPMC has been withdrawn.
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CLINICAL_TRIALS trial_result · 2014-12-03Clinical Trial Update: International Travel and the Spread of Extended-spectrum Beta-lactamase-producing Escherichia Coli
Completed clinical trial update on NCT01296165 examining the international spread of ESBL-producing Escherichia coli and associated antibiot…
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CLINICAL_TRIALS safety_alert · 2012-11-20Clinical Trial Update: Outbreak of Hemolytic Uremic Syndrome Linked to Escherichia Coli of Serotype O104:H4
An update on a clinical trial indicates an outbreak of hemolytic-uremic syndrome linked to Escherichia coli serotype O104:H4, with the study…
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CLINICAL_TRIALS trial_result · 2012-03-22Clinical Trial Update: Study of Repetitive Intestinal Lavage in Patients With EHEC Associated Hemorrhagic Colitis [NA]
The trial evaluated repetitive intestinal lavage in patients with EHEC-associated hemorrhagic colitis and is now completed.
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CLINICAL_TRIALS trial_result · 2007-03-15Clinical Trial Update: Study Evaluating Antibiotic Use in Reducing Vancomycin-Resistant Enterococci and ESBL Producing Escherichia Coli and Klebsiella Pneumoniae in Intensive Care
A completed clinical trial from Wyeth/Pfizer investigates whether targeted antibiotic use can reduce infections with vancomycin-resistant En…